SKALE Launches on Base in New Initiative for Onchain Agents

SKALE Launches on Base in New Initiative for Onchain Agents

The Defiant
The DefiantNov 25, 2025

Companies Mentioned

Why It Matters

By extending gasless, cross‑chain AI‑agent capabilities to Base, SKALE positions itself to capture developer interest and user activity despite a broader decline in AI‑agent DeFi, potentially driving adoption and network effects across multiple blockchains.

Summary

SKALE announced the launch of its "Expand" initiative on Base, Ethereum's second‑largest Layer 2 with over $4.3 billion TVL, enabling its SKALE Manager contracts to run on any EVM‑compatible chain. The platform offers gasless transactions, instant execution, and encrypted processing, allowing the same AI‑agent code and x402 payment flows to operate across multiple ecosystems without adapting to different gas models. Base brings roughly 8.4 million monthly active users, giving SKALE access to a large liquidity pool while maintaining a consistent user experience. The move follows SKALE's recent V4 upgrade and comes as AI‑agent protocol TVL has fallen from $575 million in May 2024 to $52.2 million today.

SKALE Launches on Base in New Initiative for Onchain Agents

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