Creative Destruction Lab: The Power of Mentors & Corporate Partners

HEC Paris
HEC ParisMay 5, 2026

Why It Matters

CDL’s intensive mentorship accelerates deep‑tech climate solutions, helping founders overcome scaling hurdles and delivering commercial‑ready innovations that can attract investment and drive decarbonization.

Key Takeaways

  • CDL mentors technically strong founders to build scalable businesses.
  • Diverse mentors include finance, academia, industry, and serial entrepreneurs.
  • This year’s focus: energy, carbon removal, bio‑materials, biotech climate solutions.
  • Startups must transition from lab ideas to industrial pilots quickly.
  • Mentors often fund travel, reflecting deep commitment to founder success.

Summary

Creative Destruction Lab (CDL) is a mentor‑driven accelerator that helps technically strong science and technology founders turn breakthrough research into commercial ventures. The nonprofit program pairs startups with seasoned experts to accelerate growth on a compressed timeline.

Mentors span finance, venture capital, academia, serial entrepreneurship and industry, providing a breadth of perspectives. This year CDL’s thesis targets four climate‑focused domains—renewable energy, carbon‑dioxide removal, bio‑based materials, and agricultural biotech—recognizing the need for multiple solutions across sectors.

Participants hear candid feedback such as, “they’re not looking for scientific experts, they’re looking for people who can help them overcome obstacles,” and mentors even fund their own travel to support founders, underscoring a deep personal commitment.

By guiding startups from lab proof‑of‑concept to pilot‑scale production, CDL shortens the path to market, attracts capital, and strengthens the climate‑tech pipeline, positioning investors and corporations to benefit from rapid commercialization.

Original Description

Creative Destruction Lab is a mentor-driven program designed to help science- and technology-based startups accelerate their growth.
In this conversation, speakers, including Aurélie Lustenberger, Vice President of Global Sustainability at Capgemini Invent, explore how CDL supports highly technical founders in turning breakthrough ideas into scalable businesses through the guidance of investors, scientists, entrepreneurs, industry leaders, and academics.
CDL Climate Stream Lead Maryam Khademian also highlights CDL’s focus on climate innovation, with this year’s themes spanning energy, carbon dioxide removal, materials, and biotech. From renewable energy access to bio-based alternatives and microbial solutions for agriculture, the goal is to back ventures with the potential to scale quickly and create real impact.
HEC Paris Professor Hélène Chanut-Musikas and Renaud Visage, Founding Partner at Slate Venture Capital, also talk about the unique challenges of deep tech and climate startups: moving from lab to pilot to industrial scale, proving economic viability, and staying clear on the next steps.
At the heart of it all is a strong sense of community, commitment, and generosity from mentors who are genuinely dedicated to helping founders succeed.
#CreativeDestructionLab #Startups #DeepTech #ClimateTech #Innovation #Entrepreneurship #VentureCapital #Mentorship

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