Vaginal Natural Orifice Transluminal Endoscopic Surgery versus Conventional Multiport Laparoscopy for Hemorrhagic Ovarian Cyst Rupture with Hemoperitoneum: A Multicenter Retrospective Cohort Study

Vaginal Natural Orifice Transluminal Endoscopic Surgery versus Conventional Multiport Laparoscopy for Hemorrhagic Ovarian Cyst Rupture with Hemoperitoneum: A Multicenter Retrospective Cohort Study

Research Square – News/Updates
Research Square – News/UpdatesMay 27, 2026

Why It Matters

The findings suggest vNOTES can deliver comparable surgical efficacy with reduced early pain and improved cosmetic/sexual outcomes, potentially reshaping minimally invasive gynecologic practice and patient preference.

Key Takeaways

  • vNOTES operative time comparable to conventional laparoscopy
  • 12‑hour postoperative pain lower with vNOTES (VAS 1.9 vs 3.2)
  • Genital self‑image scores higher after vNOTES (FGSIS 24.3 vs 22.3)
  • Blood loss and transfusion rates similar between techniques
  • No conversions or major complications in either group

Pulse Analysis

Vaginal natural orifice transluminal endoscopic surgery (vNOTES) has emerged as a scar‑free alternative to traditional laparoscopy, leveraging a posterior colpotomy to introduce a single‑port platform. By eliminating abdominal incisions, vNOTES promises reduced postoperative discomfort, faster mobilization, and superior cosmetic results—attributes that align with the broader shift toward patient‑centered minimally invasive procedures in gynecology.

The recent multicenter cohort of 42 women undergoing surgery for ruptured ovarian cysts provides real‑world evidence of vNOTES’ clinical parity with conventional multi‑port laparoscopy. While operative duration and intra‑operative blood loss were statistically indistinguishable, the vNOTES cohort reported markedly lower pain scores at the 12‑hour mark, translating into a smoother early recovery. Moreover, higher scores on the Female Genital Self‑Image Scale indicate that preserving vaginal integrity may positively influence patients’ sexual confidence and body image, a dimension often overlooked in surgical outcome metrics.

Despite these promising signals, the study’s retrospective design and modest sample size warrant cautious interpretation. Prospective, randomized trials are needed to confirm durability of pain reduction, assess long‑term sexual function, and evaluate cost‑effectiveness relative to standard laparoscopy. Should larger investigations corroborate these results, vNOTES could become a preferred option for selected gynecologic emergencies, offering hospitals a pathway to differentiate services while meeting growing patient demand for minimally invasive, cosmetically favorable solutions.

Vaginal Natural Orifice Transluminal Endoscopic Surgery versus Conventional Multiport Laparoscopy for Hemorrhagic Ovarian Cyst Rupture with Hemoperitoneum: A Multicenter Retrospective Cohort Study

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