
In high‑stakes healthcare, AI tools must earn physician trust through accuracy, transparency, and compliance, setting a benchmark for future point‑of‑care solutions.
The rapid rise of generative AI has sparked excitement across health tech, but clinicians remain wary of tools that could misinform patient care. Trust, regulatory compliance, and evidence‑based sourcing are non‑negotiable in a domain where errors carry life‑changing consequences. Healio’s decades‑long reputation in medical publishing gave it a unique advantage: an existing library of vetted content and a network of physicians accustomed to its editorial standards. By positioning AI as a preparation aid rather than a bedside diagnostician, Healio sidestepped the most contentious use‑cases while addressing a genuine workflow bottleneck.
Healio’s development process was grounded in real‑world feedback. A 300‑person survey uncovered an unexpected priority: physicians sought help crafting empathetic patient communication, not just clinical data retrieval. Armed with this insight, the product team sketched mockups in Figma and, within a weekend, delivered a working prototype using Cursor’s AI‑assisted coding environment. The core engine employs a hybrid Retrieval‑Augmented Generation (RAG) stack that blends lexical search, vector embeddings, and semantic matching across multiple PubMed access points, ensuring results are both comprehensive and sourced from peer‑reviewed literature. A carefully designed citation interface—subscript markers, hover previews, and progressive disclosure—gives clinicians immediate visibility into provenance, reinforcing confidence in the AI’s suggestions.
To guarantee safety and relevance, Healio instituted an eight‑judge LLM evaluation framework covering safety, medical accuracy, faithfulness, relevance, completeness, reasoning, clarity, and overall quality. However, the team emphasized that physician feedback ultimately trumps algorithmic scores, especially for nuanced communication tasks. HIPAA‑compliant input guardrails mask protected health information, while contextual advertising during query processing offers a sustainable revenue model. Healio AI’s blend of rapid prototyping, rigorous evaluation, and trust‑first design provides a roadmap for other enterprises aiming to embed AI responsibly in high‑risk professional settings.
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How do you build an AI product for an audience that can't afford to be wrong—and won't trust you until you prove it?
In this episode of Just Now Possible, Teresa Torres talks with three leaders from Healio—Jennifer Deal (SVP of Product Development), Casey Utley (Senior UX Designer), and Matthew Skepner (VP of Technology)—about how their 125-year-old medical publishing company built Healio AI, an AI-powered assistant that helps physicians prepare for patient care.
They share how a survey of 300 healthcare professionals shaped their early assumptions, why physicians surprised them by asking for help with patient communication rather than diagnostics, and how they built a working prototype in a single weekend using Cursor. You'll hear how they combined RAG with hybrid search across trusted sources like PubMed, designed citation UX that physicians actually trust, and set up eight LLM judges alongside real physician feedback to evaluate response quality.
If you're building AI for a high-stakes domain where trust, accuracy, and transparency matter more than speed, this conversation is packed with practical lessons.
Jennifer Deal – SVP of Product Development, Healio
Casey Utley – Senior UX Designer, Healio
Matthew Skepner – VP of Technology, Healio
Why physicians need AI at the point of care—and how they actually use it (hint: it's preparation, not bedside)
The surprising discovery that physicians wanted help with patient communication and empathy, not just clinical answers
Building a working prototype in a weekend with Cursor after starting with Figma mockups
How Healio's RAG system combines lexical search, vector search, and semantic search across multiple trusted sources
Why "just use PubMed" isn't simple—five different ways to access the same data, each with trade-offs
Designing citations that physicians trust: subscripts, hover states, and progressive disclosure
Serving contextual ads while the LLM processes queries—a practical monetization approach
HIPAA compliance and input guardrails for masking personal health information
Eight LLM judges for evals: safety, medical accuracy, faithfulness, relevancy, completeness, reasoning, clarity, and overall quality
Why physician feedback trumps LLM-as-judge feedback in high-stakes medical contexts
The role of the Healio Innovation Partners in ongoing discovery and validation
Healio — Medical news, education, and clinical guidance for healthcare professionals
PubMed — Database of biomedical literature
Cursor — AI-powered code editor used to build the prototype
00:00 Introduction to Jen, Casey, and Matt
01:30 What Healio Does: Medical News and Education
03:15 The Problem Space: Information Overload at Point of Care
05:45 Surveying 300 Healthcare Professionals
08:20 The Surprising Discovery: Patient Communication Over Diagnostics
11:00 How Physicians Actually Use Healio AI
13:30 Building a Working Prototype in a Weekend
16:45 The Architecture: Hybrid Search and RAG
20:10 Why Accessing PubMed Isn't Simple
23:00 Designing Trust: Citations and Source Transparency
26:30 Contextual Advertising During Query Processing
28:45 HIPAA Compliance and Input Guardrails
31:20 Eight LLM Judges: Building an Eval System
35:00 Why Physician Feedback Trumps LLM Feedback
38:15 Ongoing Discovery with Healio Innovation Partners
41:00 What's Next for Healio AI
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