35Pharma is a clinical-stage biopharmaceutical company focused on designing and developing ligand traps that target Activin x GDF signaling to treat diseases with high unmet medical need, including pulmonary hypertension, heart failure, and obesity. The company leverages protein engineering to create multi-specific traps with tailored potency and selectivity, administered via infrequent subcutaneous injections. Its research emphasizes biomarker-informed clinical trials to accelerate proof-of-principle and time to market, with operations in North America. 35Pharma is based in Montreal and Boston, and is actively advancing HS235 in its pipeline for cardiometabolic diseases and pulmonary hypertension.