Create Medicines

About Create Medicines

Create Medicines is a biotechnology company focused on in vivo immune programming using RNA-powered, LNP-delivered CAR therapies. The company develops mRNA-LNP CARs and targeted receptor/LNP technologies to directly program T cells, NK cells, and myeloid cells within the body, aiming to provide scalable, off-the-shelf immunotherapies for cancer, autoimmunity, and fibrosis. Based in Cambridge, Massachusetts, the team reports early clinical data showing uptake, expression, tolerable dosing, and mechanism of action in humans. Their pipeline encompasses multi-immune cell programming across immune lineages with a focus on rapid, broad patient access and novel therapeutic approaches.