Orna Therapeutics is a biotechnology company engineering a new class of fully engineered circular RNA (oRNA) therapeutics to expand RNA medicine beyond traditional approaches. The company focuses on in vivo delivery using its LNP platform to reach sites throughout the body, with initial emphasis on oncology, autoimmune diseases, and infectious diseases, and is based in Watertown, Massachusetts. Orna aims to deliver first-in-class RNA drugs that can treat diseases without harsh preconditioning, leveraging its panCAR in vivo CAR technology and bone marrow targeting. The organization combines scientists, engineers, and seasoned leadership to bring oRNA therapeutics to patients globally.