Sarah Guo

Sarah Guo

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Conviction (prev. Greylock); AI/product/enterprise innovation.

AI Infrastructure Early; Inference Bottlenecks Demand Customer Focus
SocialApr 13, 2026

AI Infrastructure Early; Inference Bottlenecks Demand Customer Focus

Takeaways from fireside @tuhinone @baseten did w/ @tsgiles at HumanX: - AI infra market still early - AI-native companies are post-training to achieve frontier quality-for-less/faster - inference is supply & talent constrained market - systems problem - customer centricity wins https://t.co/khcki27dHk

By Sarah Guo
AI Self‑Improvement Likely Outpaces Biological Evolution
SocialApr 6, 2026

AI Self‑Improvement Likely Outpaces Biological Evolution

when do we see self-improvement in AI research vs. biology? @LiamFedus, Cofounder @periodiclabs and former lead of post-training OpenAI, on @NoPriorsPod https://t.co/NdyTDy1ynR

By Sarah Guo
Startup Struggles Are Universal, Not Unique
SocialApr 6, 2026

Startup Struggles Are Universal, Not Unique

at least the things that really hard about your startup are likely to be hard for anyone coming after your startup, too

By Sarah Guo
AI Agents Speed Work, Exposing Costly Coordination Gaps
SocialApr 2, 2026

AI Agents Speed Work, Exposing Costly Coordination Gaps

.@gabepereyra is consistently early. intelligence is getting cheap, but judgment / coordination are $$. @harvey has an agent that picks up work off incidents, bug reports, and slack msgs on its own — and getting work done faster than anyone...

By Sarah Guo
TS‑cleared Engineers Needed for Urgent, Funded Startup
SocialApr 1, 2026

TS‑cleared Engineers Needed for Urgent, Funded Startup

Looking for TS cleared engineers that want to work on a funded, urgent startup with big mission and killer people. Must be willing to live in CA, WA, HI for now

By Sarah Guo
Supply Chain Hacks Cripple Major Security and AI Tools
SocialApr 1, 2026

Supply Chain Hacks Cripple Major Security and AI Tools

Rundown of the very bad week in security: - TeamPCP (sophisticated hacking group) attacks: Hackers broke into the system that builds a oss popular security scanning tool called Trivy. This was a supply chain attack (when bad code is slipped...

By Sarah Guo
Startups Need Labs Teams or Risk Becoming Enterprise SaaS
SocialMar 26, 2026

Startups Need Labs Teams or Risk Becoming Enterprise SaaS

if you’re a startup in 2026 and you don’t have a “labs” group, you might as well be enterprise SaaS

By Sarah Guo
Calling Non‑Tech Users: Beta Test AI Empowerment Tool
SocialMar 23, 2026

Calling Non‑Tech Users: Beta Test AI Empowerment Tool

any nontechnical folks want to get more comfortable/powerful in their use of AI and want to be a beta user on something I made?

By Sarah Guo
Silicon Ducking: Using Thought‑Tuned AI for Better Decisions
SocialMar 22, 2026

Silicon Ducking: Using Thought‑Tuned AI for Better Decisions

is talking to a model fine-tuned on your own thoughts (say, for investment judgement) a sign of madness? given this kind of iteration can help models, maybe it helps humans "silicon ducking" instead of rubber ducking

By Sarah Guo
AI Agents Trigger Engineering Phase Shift and New Research Paradigm
SocialMar 20, 2026

AI Agents Trigger Engineering Phase Shift and New Research Paradigm

Caught up with @karpathy for a new @NoPriorsPod: on the phase shift in engineering, AI psychosis, claws, AutoResearch, the opportunity for a SETI-at-Home like movement in AI, the model landscape, and second order effects 02:55 - What Capability Limits Remain? 06:15 -...

By Sarah Guo
Notion Founder Unveils Expanded Vision Amid AI Surge
SocialMar 18, 2026

Notion Founder Unveils Expanded Vision Amid AI Surge

ICYMI, last week’s No Priors: Notion founder @simonlast on the company’s expanded vision, given rapidly growing ai capabilities

By Sarah Guo
Star-Studded AI Founder Lineup for Conviction Retreat
SocialMar 14, 2026

Star-Studded AI Founder Lineup for Conviction Retreat

guys it's a 🔥 lineup for @Conviction Embed retreat: @btaylor (Founder, Sierra & Chairman, OpenAI) @mikeyk (Labs, Anthropic & Founder, Instagram) @parkerconrad (Founder, Rippling) @zackmziegler (Founder, OpenEvidence) John Haddock (Chief Business Officer, Harvey) @GuptaRK22 (Founder, Ithaca) @Karpathy (Sensei, Researcher) @milichab (Cursor, xAI)

By Sarah Guo
AI Agents Now Autonomously Execute Internet Tools in Production
SocialMar 12, 2026

AI Agents Now Autonomously Execute Internet Tools in Production

An AI agent can now discover a tool on the internet, call it, and take action in production. Two years ago unthinkable, today that's a slow Tuesday night. Every enterprise will need a control plane for AI -- we backed...

By Sarah Guo
Karpathy Returns to NopriorsPod: Anticipating Coding Agent Insights
SocialMar 12, 2026

Karpathy Returns to NopriorsPod: Anticipating Coding Agent Insights

excited to have sensei @karpathy back on @nopriorspod tomorrow. what wisdom shall we glean? (yes, yes, wth is going on with coding agents)

By Sarah Guo