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Biotech Investor

Biotech Investor

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Biotech investment educator; former biotech executive and banker sharing insights and lessons for investing in the sector.

Recent Posts

Understanding ORR and RECIST v1.1 Response Metrics
Social•Jan 20, 2026

Understanding ORR and RECIST v1.1 Response Metrics

Investors will often see ORR quoted or displayed for oncology clinical trial results for solid tumors Here's what the CRs/PRs/SDs mean at a high level These are assessed on scans I'm using RECIST v1.1 definitions #learnbiotechinvesting #biotech #investing #BiotechPrometheus https://t.co/1YAoHGXujW

By Biotech Investor
Accelerated & Breakthrough Save Time; Fast Track Doesn't
Social•Jan 19, 2026

Accelerated & Breakthrough Save Time; Fast Track Doesn't

How much time do FDA expedited designations save? Accelerated approval and Breakthrough status save a statistically significant amount of time. But Fast track does not Investors should keep this in mind #learnbiotechinvesting #biotech #investing #BiotechPrometheus https://t.co/tmxBBt7Izi

By Biotech Investor
Biotech Pre‑funded Warrants Raise Cash, Delay Dilution
Social•Jan 18, 2026

Biotech Pre‑funded Warrants Raise Cash, Delay Dilution

Since most biotechs aren't profitable they often use warrants (including pre-funded) to raise capital while mitigating short term dilution But what is a warrant and what are their implications? #learnbiotechinvesting #biotech #investing #BiotechPrometheus A warrant is a security that gives the...

By Biotech Investor
Plan Biotech Catalysts Early to Capture Stock Moves
Social•Jan 17, 2026

Plan Biotech Catalysts Early to Capture Stock Moves

Investors should know WHAT will move a stock and WHEN, especially in biotech with the outsized moves. Build your catalyst calendar ahead of time. You won't have time to thoughtfully analyze the data when it hits #learnbiotechinvesting #biotech #investing #BiotechPrometheus https://t.co/iFc6oc4jll

By Biotech Investor
Oncology M&A: Early‑Stage Deals Still Command Higher Multiples
Social•Jan 16, 2026

Oncology M&A: Early‑Stage Deals Still Command Higher Multiples

In #oncology #M&A higher 5-yr forward revenue multiples occur for earlier stage companies, though P3 is an exception Recently multiples have declined reflecting lower valuations, later stage acquisitions, and smaller market opportunities What are some other reasons? #learnbiotechinvesting #biotech #investing #BiotechPrometheus

By Biotech Investor
Phase 3 Data More Reliable; P2 Placebos Often Variable
Social•Jan 14, 2026

Phase 3 Data More Reliable; P2 Placebos Often Variable

Another reason a P3 study can fail while a P2 was successful is that P2 placebo groups, with narrower eligibility criteria & fewer patients, often have more variable placebo-adjusted effects Use Phase 3 data, often on drug labels, to make comparisons;...

By Biotech Investor
Factor Development Risk with Probability of Success
Social•Jan 13, 2026

Factor Development Risk with Probability of Success

Incorporating Probability of Success (PoS) is a unique aspect of #biotech valuation investors must be aware of. It tries to factor development risk into revenue and cost assumptions. Here is a table of PoS values: #learnbiotechinvesting #investing #BiotechPrometheus https://t.co/Sv8XodkWXg

By Biotech Investor
Transparent Valuation Links Investor Thesis to Share Price
Social•Jan 10, 2026

Transparent Valuation Links Investor Thesis to Share Price

Transparency in valuation is a good thing. People may have different assumptions but it’s important to understand how your thesis as an investor translates into a share price. Thank your for posting @Biotech2k1

By Biotech Investor
Context and Competition: Key Framework for Biotech Investors
Social•Jan 10, 2026

Context and Competition: Key Framework for Biotech Investors

The context of the data matter. How does it stack up against the competition? Is there other competition? This framework will help investors organise their thoughts #learnbiotechinvesting #biotech #investing #BiotechPrometheus https://t.co/jKBHRAXsch

By Biotech Investor
Know the FDA Process: Key to Biotech Investment Success
Social•Jan 9, 2026

Know the FDA Process: Key to Biotech Investment Success

Investors should understand the #FDA regulatory process well. Here is a quick summary At each step investors should ask themselves if the company is developing things in a way that will satisfy the FDA Until a drug is approved the FDA is...

By Biotech Investor