Jordan Feigenbaum, MD
Physician/coach (Barbell Medicine); evidence-led posts on diet, peptides, vitamins/supplements, and practical nutrition.
Nattokinase Shows No Benefit in Rigorous Trial
The “300% better than statins” number comes from a 76-person Chinese study (Ren 2017) with no placebo arm. The “1,000+ people” study is a separate retrospective one. Unclear if the OP knew this and did it intentionally. The only large, randomized, double-blinded, placebo-controlled trial (Hodis 2021, 265 people, 3 years of serial carotid ultrasound) found nattokinase did nothing to CIMT, arterial stiffness, BP, or other lab marker vs placebo.
Study Shows Mechanism, Not Creatine Risk for Endometriosis
Creatine promotes endometriosis” is making the rounds. That’s not what the paper shows. It’s a mechanism study in cells and mice. Here’s why it says nothing about your creatine tub. 🧵
Most Americans Skeptical of Pesticide Risks; Dirty Dozen Debunked
Only 3 in 10 Americans believe the health benefits of eating conventionally grown produce outweigh the pesticide risk. In a 2024 survey of 1,000 U.S. adults, 7 in 10 were either ambivalent, opposed, or unsure. Every spring, the Environmental Working Group...
Testosterone Levels Stable, Recent 9% Rise Tied to TRT Surge
Based on accurate testing in the last 30 years, no real change in testosterone at the population level. In the last 10 years however, there’s been a ~9% increase, which is likely due to the quadrupling of TRT prescriptions in...
GLP‑
This is nonsense. GLP1’s produce weight loss, about 1/4 of that is lean mass, which itself is not all muscle. Muscle quality (force production relative to size) improves with GLP1 use, which means more strength in a group of people...
Peptide Drugs Require Robust Safety and Efficacy Evidence
In response to suggesting peptide drugs should have good evidence on safety and efficacy in order to weigh the risks and benefit…