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Podcast on molecular programming and DNA nanotechnology (biomolecular nanotech). Geared toward early-career researchers, it features discussions and panels on designing molecular systems and nanoscale computing.
In this episode, Professor Megan Engel discusses how machine learning and modern optimization techniques can streamline the creation of coarse‑grained molecular models, building on the challenges faced by the original oxDNA developers. She explains shortcuts that reduce the labor‑intensive parameterization of force fields and shares her vision for designing out‑of‑equilibrium molecular machines that exploit nanoscale forces. Engel also touches on her interdisciplinary background—from astrophysics to DNA nanotechnology—and even weaves in her love of J.R.R. Tolkien lore.