Talk Python to Me

Talk Python to Me

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Interviews on Python in production, often touching data pipelines, big data tooling, and ML.

#546: Self Hosting Apps for Python People
PodcastApr 27, 20261h 3m

#546: Self Hosting Apps for Python People

In this episode, Michael Kennedy talks with Alex Kretzmar, head of DevRel at Tailscale and co‑founder of linuxserver.io, about the state of self‑hosting in 2026. They explore why many users are moving their digital lives behind their own walls, highlight...

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#545: OWASP Top 10 (2025 List) for Python Devs
PodcastApr 16, 20261h 6m

#545: OWASP Top 10 (2025 List) for Python Devs

In episode 545, Michael Kennedy and security expert Tanya Janka unpack the newly released OWASP Top 10 (2025) with a focus on Python developers. They walk through each of the ten categories—highlighting fresh additions like supply‑chain attacks and exceptional condition...

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#544: Wheel Next + Packaging PEPs
PodcastApr 10, 20261h 11m

#544: Wheel Next + Packaging PEPs

In this episode, Michael Kennedy talks with Jonathan Decker (NVIDIA), Ralph Gommers (QuantSight), and Charlie Marsh (Astral) about WheelNext, a set of PEPs that let Python packages declare hardware requirements so installers like UV can automatically select the optimal binary....

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#540: Modern Python Monorepo with Uv and Prek
PodcastMar 13, 20261h 2m

#540: Modern Python Monorepo with Uv and Prek

In this episode, host Michael Kennedy talks with Apache Airflow core contributors Yarek Patuk and Amag Desai about how they manage one of the world’s largest Python monorepos—over a million lines of code and 100+ sub‑packages—using modern tooling like UV,...

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#534: Diskcache: Your Secret Python Perf Weapon
PodcastJan 13, 20261h 14m

#534: Diskcache: Your Secret Python Perf Weapon

In this episode Michael Kennedy talks with Vincent Warmerdam about DiskCache, a SQLite‑backed, dictionary‑like cache that persists to disk and works safely across threads and processes. They explain how DiskCache’s @cache.memoize decorator and FanoutCache sharding enable cheap, high‑performance caching for...

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