News•Feb 24, 2026
RHR: The Gut-Brain Connection: How Your Microbiome Affects Your Mental Health
Emerging research redefines depression as an inflammatory disorder linked to gut health. Cytokine‑driven inflammation often originates from increased intestinal permeability, allowing endotoxins to reach the brain. Short‑chain fatty acid butyrate and specific probiotic strains, notably Bacillus coagulans, have shown promise in reducing inflammation, restoring barrier function, and improving mood scores. Clinical protocols typically combine diet, targeted pre‑/pro‑biotics, and functional testing over 8‑12 weeks alongside conventional therapy.
