Gradient Dissent
An AI and machine learning podcast by Weights & Biases featuring candid conversations with AI practitioners and researchers. Host Lukas Biewald (W&B co-founder) interviews prominent figures in machine learning about their research breakthroughs, deployment challenges, and lessons learned. Topics span deep learning, MLOps, NLP, computer vision and beyond – with a focus on real-world insights for ML engineers and enthusiasts.
He Raised $70M to Cure Every Disease With AI
In this episode, host Lucas Wald talks with Sam Rodriguez, founder and CEO of Edison Scientific and Future House, about using AI agents to accelerate biological research and drug discovery. Rodriguez explains how his team built the multi‑agent system Cosmos, which can run the full scientific loop—from hypothesis generation to experiment planning and analysis—and has already produced thousands of novel findings, including a Nature‑published treatment hypothesis for age‑related macular degeneration. He argues that AI can remove talent as the bottleneck in biology, enabling leaner pharma pipelines, and discusses the evolution from a nonprofit research model to a for‑profit spin‑out to scale the technology. The conversation also touches on the limits of current AI, the need for focused research organizations, and the broader vision of curing diseases and mapping the brain.
The $64M Bet on an AI That Has to Be Right | Carina Hong, CEO of Axiom
In this episode, Lukas Biewald explores the evolving AI ecosystem through a series of interviews with founders and CEOs of leading AI infrastructure and application companies, including Axiom, Rerun, Runway ML, Baseten, CoreWeave, Surge AI, Glean, DeepL, GitHub, and Cursor. The conversations...
Inside the $41B AI Cloud Challenging Big Tech | CoreWeave SVP
In this episode, CoreWeave SVP discusses how the company has built a $41 billion AI cloud infrastructure that rivals the big tech giants, focusing on its strategy of offering flexible, high‑performance GPU compute and specialized AI services for enterprises. He explains...
Why Physical AI Needed a Completely New Data Stack
In this episode, Lukas Biewald interviews a lineup of AI leaders—from Arvind Jain of Glean, who details the shift from enterprise search to agentic AI that grasps internal workflows, to Jarek Kutylowski of DeepL, who explains how a small team...
The Engineering Behind the World’s Most Advanced Video AI
In this episode, Lukas Biewald interviews the CEO and founder of Surge AI about how their company is redefining data labeling for next‑generation large language models. They explore why traditional annotation pipelines fail, the importance of inter‑annotator agreement, and Surge’s...
The CEO Behind the Fastest-Growing AI Inference Company | Tuhin Srivastava
In this episode of Gradient Dissent, Lukas Biewald talks with Tuhin Srivastava, CEO and founder of Baseten, one of the fastest-growing companies in the AI inference ecosystem. Tuhin shares the real story behind Baseten’s rise and how the market finally...
What’s the Path to AGI? A Conversation with Turing Co-Founder and CEO Jonathan Siddharth
The post serves as a curated roundup of recent Gradient Dissent podcast episodes, featuring AI founders and CEOs—from Surge AI’s Jonathan Siddharth on AGI pathways to leaders at Glean, DeepL, GitHub, and more—who share origin stories, challenges, and how their...
Vercel’s CEO & Founder Guillermo Rauch on the Impact of AI on Web Development and Front End Engineering
The post is a curated roundup of recent Gradient Dissent podcast episodes, each featuring AI‑focused founders and CEOs discussing their companies’ breakthroughs—from data labeling at Surge AI and enterprise search at Glean to neural translation at DeepL and developer tools...
Snowflake’s CEO Sridhar Ramaswamy on 700+ LLM Enterprise Use Cases
The post is a curated roundup of recent Gradient Dissent podcast episodes where host Lukas Biewald interviews a range of AI‑focused CEOs and leaders—from Surge AI’s founder on data labeling, Glean’s CEO on enterprise search, DeepL’s chief on translation, to...
Elevating ML Infrastructure with Modal Labs CEO Erik Bernhardsson
The post curates a series of Gradient Dissent podcast episodes where host Lukas Biewald interviews a range of AI and tech leaders—from data‑labeling pioneer Surge AI to translation powerhouse DeepL, GitHub’s Copilot team, and AI‑driven cybersecurity and defense experts. Each...
From No-Code to AI-Powered Apps with Airtable’s Howie Liu
The post is a curated roundup of recent Gradient Dissent podcast episodes, each featuring a different AI leader—from Surge AI’s Howie Liu to GitHub’s Thomas Dohmke—discussing their companies' origins, breakthroughs, and the broader impact of AI on fields like data...
Launching the Fastest AI Inference Solution with Cerebras Systems CEO Andrew Feldman
The post is a roundup of recent Gradient Dissent podcast episodes, each featuring a different AI leader—from Surge AI’s Andrew Feldman to GitHub’s Thomas Dohmke—discussing their companies' breakthroughs, challenges, and visions for the future of AI. It highlights recurring themes...
Reinventing AI Agents with Imbue CEO Kanjun Qiu
The post curates a series of Gradient Dissent podcast episodes where host Lukas Biewald interviews leading AI founders and CEOs—from Surge AI and Glean to DeepL, GitHub, and CrewAI—exploring how AI agents, data labeling, and model training are reshaping enterprises...
From Startup to $1.2B with Lambda’s Stephen Balaban
The post lists recent Gradient Dissent podcast episodes where host Lukas Biewald interviews CEOs and founders of AI‑focused companies—from Surge AI’s Stephen Balaban on data labeling to DeepL’s Jarek Kutylowski on translation, GitHub’s Thomas Dohmke on Copilot, and others covering...
Harnessing AI for Legal Practice with CoCounsel’s Jake Heller
The post is a curated roundup of recent Gradient Dissent podcast episodes, each featuring AI leaders discussing how artificial intelligence is reshaping their fields—from data labeling at Surge AI and enterprise search at Glean to translation at DeepL, software development...