News•Mar 10, 2026
MindImmune Lands ADDF Funding to Harness the Immune System Against Alzheimer’s
MindImmune Therapeutics secured a $5 million investment from the Alzheimer’s Drug Discovery Foundation to advance its lead candidate, MITI‑101, which targets peripheral immune pathways implicated in Alzheimer’s neuroinflammation. Unlike conventional amyloid‑ or tau‑focused approaches, the Cambridge‑based biotech aims to block CD11c‑positive innate immune cells from entering the brain, thereby preventing synaptic damage. Preclinical mouse studies demonstrated that inhibiting these cells reduces markers of synaptic deterioration. The funding will support IND‑enabling work and set the stage for early‑stage clinical trials later this year.
By Longevity.Technology
News•Mar 10, 2026
The Mouth-Body Connection: Why Oral Health Matters for Longevity
The Longevity.Technology UNLOCKED episode highlights the mouth as a pivotal gateway to overall health, linking nasal breathing, oral microbiome, and dental habits to inflammation, sleep quality, and metabolic function. Clinicians Dr. Aoife Stack and Dr. James Goolnik argue that chronic...
By Longevity.Technology
Deals•Mar 10, 2026
MindImmune Therapeutics Secures $5M Funding From ADDF for Alzheimer’s Immunotherapy
Cambridge‑based biotech MindImmune Therapeutics announced a $5 million investment from the Alzheimer’s Drug Discovery Foundation to advance its lead candidate MITI‑101, an antibody targeting peripheral immune pathways in Alzheimer’s disease. The funding will support IND‑enabling studies and early‑stage clinical development, building...
Longevity.Technology
News•Mar 9, 2026
Forever Young Explores the Longevity Revolution
The documentary "Forever Young" arrives as the longevity field moves from lab breakthroughs to public policy and everyday life. Featuring top geroscientists from the Buck Institute, Harvard and Stanford, the film argues that lifestyle and environment outweigh genetic destiny in...
By Longevity.Technology
Video•Mar 9, 2026
How Your Mouth Shapes Your Longevity
In a recent conversation, Dr. Aoife Stack and Dr. James Goolnik argue that oral and airway health are foundational to longevity, influencing sleep, metabolism, immunity, and brain function. They explain how nasal breathing, tongue posture, and myofunctional therapy improve airway...
By Longevity.Technology
News•Mar 6, 2026
Longevity and Disease Insights Now in 20/20 BioLabs Blood Test
20/20 BioLabs has launched OneTest for Longevity, a lab‑developed blood test that combines inflammatory biomarkers, lifestyle data, and AI to deliver personalized aging and chronic disease risk insights. The platform leverages IBM's watsonx.ai and the University of South Carolina's Dietary...
By Longevity.Technology
News•Mar 6, 2026
Sleep Rhythms and Dementia Risk Link Emerges
Alzheimer’s disease now affects 55 million people worldwide, with 10 million new cases each year, prompting researchers to explore upstream triggers beyond genetics. Texas A&M scientists have shown that chronic circadian disruption in animal models drives microglia into a stress‑primed, inflammatory state,...
By Longevity.Technology
Video•Mar 6, 2026
ARPA-H Funding, Brain Wearables, & Nanotech Biosensing | Longevity News Roundup — Week 10, 2026
The U.S. ARPA‑H agency announced a $144 million PROSPR program to accelerate human health‑span trials, awarding $30.8 million to Cambrian BioPharma for a next‑generation rapamycin analog and $22 million to Linnaeus Therapeutics for repurposed oncology drugs. Meanwhile, startups are pushing wearable and digital...
By Longevity.Technology
News•Mar 5, 2026
Is Neurodegeneration a Systemic Metabolic Condition?
British biotech Vesalic reports a breakthrough that links amyotrophic lateral sclerosis (ALS) to a systemic metabolic dysfunction detectable in blood extracellular vesicles (EVs). The company says the EVs carry a toxic lipid cargo that harms motor neurons, and its blood‑based...
By Longevity.Technology
Video•Mar 2, 2026
🎙️ Lifestyle Medicine and Healthspan
Allen Law outlines lifestyle medicine’s six pillars—diet, exercise, stress management, restorative sleep, avoidance of harmful substances, and nurturing social connections. He argues that consistent daily habits across these areas can significantly boost healthspan, the period of life spent in good...
By Longevity.Technology
Video•Mar 2, 2026
Designing Healthspan: Inside the Morrow Model
The episode features Allen Law and Dr. William Tan discussing Morrow’s preventive health platform that integrates diagnostics, AI coaching, and community to turn biomarker data into daily habits. They critique modern medicine’s reactive nature and outline six pillars of lifestyle...
By Longevity.Technology
Video•Mar 1, 2026
🎙️ Nanoplastics in the Human Brain
Researchers published in the Journal of Clinical Investigation that nanoplastics can traverse the blood‑brain barrier and accumulate within human brain tissue. The study identified these ultra‑small particles, comparable in size to viruses, in both young and older individuals. Notably, brains...
By Longevity.Technology
Video•Feb 27, 2026
🎙️ Targeting Inflammaging with AI
Scienta introduced EVA, an AI model designed to combat inflammaging. EVA integrates multi‑omic preclinical and clinical data to map inflammatory pathways linked to age‑related diseases. The platform proposes novel therapeutic targets and compounds aimed at restoring youthful immune signaling. The...
By Longevity.Technology
Video•Feb 27, 2026
Nanoplastics, mRNA Therapy, & Drug Approvals | Longevity News Roundup — Week 9, 2026
Recent longevity news highlights nanoplastics in brains, a pioneering mRNA therapy, and regulatory shifts accelerating anti‑aging drug development. Researchers found ultra‑small plastic particles accumulating in Alzheimer‑affected brain tissue, independent of age. Klothea launched a phase 1b trial of AKL003 mRNA to...
By Longevity.Technology