
Targeting Aging: Epigenetic Reprogramming Tackles Disease Root
Aging is arguably the root cause of most major diseases. Our cells lose function as we age, allowing various conditions to manifest, which is why most major diseases correlate with age. Yes, it is more complex than this, but this is a major component. @newlimit is working on treating a root cause of disease (aging) using epigenetic reprogramming.
Earn 25% of Friends' Swap Fees on Base
Referrals are live on @baseapp. Refer your friends to earn 25% of their swap fees. They get a 10% fee discount too. (Install the app, then tap your profile photo in top left, then "Invite Friends")
402‑fold Payment Scalability via Flexible On‑chain
Big scalability improvement for agentic payments: x402 "Upto". Pre-authorize up to an amount, use as much as you want, the final amount gets settled onchain.
Base Hits 5k TPS, Becomes Top Chain for Trading
Base is now even faster (5k TPS and growing). Base is the best chain for trading, payments, and agents.

Bipartisan Push Urges Passage of the Clarity Act
We agree. Thank you @SecScottBessent for saying it. It's time to pass the Clarity Act. Grateful for all the bipartisan work among Senators and staff over the past several months to make this a strong bill. https://t.co/YBKebDkq8B
Coinbase Custodian for Morgan Stanley Bitcoin Trust Signals Institutional Adoption
Coinbase has been named as a custodian for the @MorganStanley Bitcoin Trust. Institutional adoption continues, regardless of short term price effects.
Build the Future of Stablecoin Payments in SF
Register and come build the future of stablecoin payments with us in SF April 28
One Yes Can Ignite Internal Innovation, Not One No
Steve Wozniak famously went to his boss at HP and said they should build a personal computer. They said no, so he left to found Apple. It’s a lesson for leaders: one "no" shouldn't kill a contrarian but right idea...
Key Frontier Biology Gaps Holding Back Civilization’s Leap
Some of the most underinvested areas in frontier biology that could accelerate civilizational progress: - Cheap, large-scale DNA synthesis (writing entire chromosomes or full organisms) - Real-time, non-destructive RNA sequencing in living cells - Highly accurate AI-powered polygenic scores for complex traits (disease...
AI Agents Will Soon Need Crypto Wallets via X402
Every AI agent deserves a crypto wallet. In fact, there will be more AI agents transacting online than humans very soon. x402 is the internet payments layer (which has been missing for the last 30 years), and will enable this. The new...
Base Launches 24/7 Global Economy with Stablecoin Payments
Base is powering a new global economy with: - 24/7 markets for all kinds of assets - Cheap, instant, private, global stablecoin payments - The best builder ecosystem for humans and agents More details on how we'll get there in the blog.
Bold Bets on Base Chain Spark Financial System Transformation
🎯 We're going to keep making bold bets with @base chain and @baseapp. This transformation of the financial system is just getting started.

One Tool Unlocks Global Decentralized Finance Access
We live in an incredible time where this is all you need to access decentralized financial services, accessible anywhere in the world. https://t.co/aRyhO8SBa0
Bitcoin Serves as Inflation Check, Bolstering Dollar Dominance
Bitcoin is a check and balance on inflation. When spending gets too far out of hand, capital moves to Bitcoin. Competition benefits customers, and this applies even in the market for money. In this way, Bitcoin will help preserve dollar dominance.
Progress Requires Stepping Into Fog, Not Seeing All
Working on something ambitious is like climbing a mountain that’s covered in fog. You can't see a clear path to the top. You have to take a few steps into the unknown to be able to see the next few steps...