Spam Texts Masquerading as Friends Signal Platform's
Latest sign of the end of x: overwhelming number of spam private text messages supposedly from people I know, but in fact, pure spam/phishing
United's Spotty Wi‑Fi Gets Starlink Upgrade Hope
Apparently @united upgrading WiFi to @Starlink @elonmusk - can’t happen soon enough bc service is spotty to the point of embarrassment; no idea how so many Bay Area tech folks (big users of united) put up with it.

Military Ends Mandatory Flu Shots, Reversing Centuries‑Old Policy
1/2 The military moving backwards on vaccines (recent announcement making flu vax no longer mandatory) reverses a long history that goes back to Washington and smallpox, and has continued to the (almost) present day - see below from @EvidenceOpen ...
Our Bodies Accumulate DNA Replication Errors over a Lifetime
Your DNA replicates a lot between the time you're a fertilized egg and the 30T or so (human) cells in your adult body; fidelity is high but not perfect. In today's @WSJ I review a new book taking a deep...
Comprehensive New Book Explores Somatic Mutation
Just out - my latest @WSJBooks review - a new book offering comprehensive consideration of somatic mutation -> https://t.co/ptkWfPKemN @zakkohane
New Book Traces DeepMind’s Rise in AI History
This is a fantastically interesting ep of Ground Truth as @EricTopol interviews @scmallaby about Mallaby's new book The Infinity Machine - intellectual history of AI focused on @demishassabis & @GoogleDeepMind. https://t.co/uudKbqUKF6 cc @zakkohane @CadeMetz
Primary Care's Heart: Connection, Stories, and Human Agency
Lovely final ep of @LisaRosenbaum17's perceptive @NEJM NOS pcast series on primary care: https://t.co/vYhK3QN5ce Ep has it all for me: agency, SDT, call of stories, limitations of metrics, value of connection & longitudinal relationships; cx of medicine; warmth; love. @zakkohane

Early GLP‑1 Rodent Studies Showed Weight Loss Before Diabetes Focus
I don't think this is correct from @nytimes op-ed on GLP-1s - wt loss known from early rodent studies involving injection into CSF as I recall. DM2 more tractable as initial pharma indication, esp at that time - many still...
Podcasts Lose Appeal as Ads Overwhelm Content
Starting to find podcasts way less enjoyable than I used to now that they are increasingly stuffed full of ads - at times feels like more ads than content.
Busy Biotech Day Highlights Promising Advances and Insightful Commentary
As usual, excellent summary by @ldtimmerman @timmermanreport of busy and promising biotech news day - as always delivered w insight and heart (especially thoughtful comments re: revmed drug in context of poignant recent @BenSasse interview)
Denial Delays Fuel Physician Burnout and Payor Tension
Having seen so many MD requests for either prescriptions or procedures reflexively denied initially, and requiring considerable additional effort from MDs office to get coverage, it's easy to appreciate both MD burnout and hostility towards payors.
Alpha‑gal Allergy: Tick Bites Turn Meat Into Danger
Fascinating episode of the always fun @TheSporkful pcast, usually focused on an interesting aspect of food, today - it's medical epi, a really engaging, scary, interesting story about alpha gal https://t.co/zZFGjJ1gdl featuring red meat & Lone Star ticks. @ValStoneMD @mvhospital_
Aging Unavoidable, But Your Agency Shapes Its Impact
Essential 🧵 from @hjluks - aging may not be optional but the way you approach & respond to it is-profound opportunities as he describes to significantly mitigate many of the effects. Central here is **agency**-recognizing all you can do, &...

WHOOP AI Coach Shares Worthy Amb
Encouraged to see this perspective (articulated as an ambition-and I’d argue a very worthy one) from @WHOOP’s AI coach in response to question… @EmilyBreslow @willahmed https://t.co/YTdRL7pIgh

Prioritize Any Exercise Over Ideal Balance
Love this from Eric Verdin @BuckInstitute highlighting evidence base for health value of exercise. Would strongly emphasize value of some exercise vs obsessing w "ideal balance" (cc @BStulberg , @ZekeEmanuel) Also remember sleep, nutrition; also connection/purpose, agency https://t.co/N6QYgecYjR