Lactate: Key Regulator Shaping Health and Disease
After 30 years studying lactate, I have learned this: Lactate is not just a metabolite. It is a major regulator in the human body body. It can support metabolic health or contribute to disease. Same molecule. Different context. Lactate has been the most misunderstood molecule in biology. If you want to learn more about lactate and its multiple roles, link to my Substack article here 👇 https://t.co/WWDf5nntRm
Detect Polyps Early, Prevent Cancer Decades Later
March has been colorectal cancer awareness month. A reminder of the work of Bert Vogelstein, one of the most cited cancer researchers in history. He showed that colorectal cancer is a slow, stepwise process (often over 20–25 years): normal tissue ➡️...
Lactate: Misunderstood Molecule, Actually Helps, Not Harms
"Lactate was at the scene of the crime but was not the criminal. It was actually trying to help" Lactate: The Most Misunderstood Molecule in Biology👇 https://t.co/3skDRDEuqw
Zone 2: Optimal Metabolic Equilibrium for Most
A mechanistic articulation on why zone 2 is the maximum metabolic equilibrium state for most people. 👇 https://t.co/W8MxJC40Yi
Lactate: The Most Misunderstood Molecule in Physiology
The lactate story. The Most Misunderstood Molecule in Human Physiology. Coming up tomorrow on Substack https://t.co/cyvmQexhzr
Beyond VO₂max: Rethinking Performance and Longevity
Working on a new article for my Substack. Those of us working with elite athletes have relied on our good old friend VO₂max for decades. It’s essential, but it’s not the full picture. Now that VO₂max has re-emerged in the world of longevity,...
Guard Your Thoughts Like Health, Shape Your Character
Great message from Marcus Aurelius reminding us to guard our thoughts. If our thoughts are filled with resentment, fear, envy or bitterness, those impressions slowly shape our character. They become our emotional baseline. Over time they define how we see the...
Both Zone 2 and HIIT Essential for Peak Power
Many years of TrainingPeaks data from top cyclists I have worked with show a consistent pattern: ~40–60% of the best 5, 10 and 20 min power outputs were achieved during training in individually prescribed HIIT sessions ~40–60% occur during races. In simple...