John Carroll

John Carroll

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Veteran biotech journalist; founder of Endpoints News and known for insider industry insights.

Senior FDA Official’s Attack Sparks Debate Over Leadership
SocialMar 6, 2026

Senior FDA Official’s Attack Sparks Debate Over Leadership

Gee, who could this "senior FDA official" be? It's a head scratcher. But he might tell Vinay Prasad that thinly veiled attacks against, oh, UniQure, and going off on advisory councils is a great way of keeping the political pot...

By John Carroll
FDA Guidance Boosts Biotech, HHS Calls It Fake
SocialMar 3, 2026

FDA Guidance Boosts Biotech, HHS Calls It Fake

Did the FDA’s individualized therapy guidance put a spike in the heart of a startup biotech? Fake news, says the HHS. Yeah, it did, says an insider. Exclusive from @RLCscienceboss and @Jared_Whitlock https://t.co/IN9o4VIp03

By John Carroll
Watch Webinar Linking Top 100 Biotech VCs Insights
SocialFeb 27, 2026

Watch Webinar Linking Top 100 Biotech VCs Insights

Here's the link to watch yesterday's webinar on venture capital, a companion to this year's top 100 biotech VCs list with @ChrisDoko Lots of positive feedback here. Post your thoughts. https://t.co/c16y04mFsD

By John Carroll
Novo's Missteps Echo Bristol Myers' Strategic Failure
SocialFeb 27, 2026

Novo's Missteps Echo Bristol Myers' Strategic Failure

Elizabeth Cairns' piece on $Novo is reminiscent of Bristol Myers' strategic fail against Merck and Keytruda. They were focused on the wrong things, made bad trial design decisions and got stuck in the mud of their own making. Everyone should...

By John Carroll
Biotech VC Webinar Launches with Top Experts, Thousands Registered
SocialFeb 26, 2026

Biotech VC Webinar Launches with Top Experts, Thousands Registered

We'll be gearing up today's webinar on biotech venture capital at the top of the hour. Great guests, great topics. If this is a central issue in your life, tune in. Thousands have signed up already. https://t.co/c16y04mFsD

By John Carroll
Makary Slams FDA, Defends Rare Disease Drugs Amid Controversy
SocialFeb 26, 2026

Makary Slams FDA, Defends Rare Disease Drugs Amid Controversy

You've got to watch this Makary interview on CNBC. He attacks a drug, hits the Old FDA and circles all the wagons around Vinay Prasad, who "loves President Trump" and faces a fatwa (WSJ). Makary is getting major props for...

By John Carroll
GSK's New CEO Targets Proven Science, Eyes Obesity Drugs
SocialFeb 25, 2026

GSK's New CEO Targets Proven Science, Eyes Obesity Drugs

The FT's report on GSK's $950M deal to buy 35Pharma and its pulmonary arterial hypertension drug includes an interesting unnamed insider's quote that new CEO Luke Miels is going after assets where "the science is relatively settled." Maybe leaning into...

By John Carroll
Rival Drug Wins, Costs Us Marketing Gold
SocialFeb 23, 2026

Rival Drug Wins, Costs Us Marketing Gold

That feeling you get when you run a head-to-head study and the rival drug beats you out. Spending a fortune to hand your competitor a marketing message. Sometimes it feels like $NOVO is snake bit. $LLY https://t.co/gGUjl6iqPg

By John Carroll
Finalizing Top 100 Biotech VCs, Join 2026 Webinar
SocialFeb 18, 2026

Finalizing Top 100 Biotech VCs, Join 2026 Webinar

We're wrapping up the fact checking process for our annual Top 100 biotech VCs list and prepping for our companion webinar on VC investing in 2026. If this is a topic near and dear to your heart, be sure to...

By John Carroll
FDA's Erratic, Unpredictable Decisions Undermine Drug Regulation
SocialFeb 18, 2026

FDA's Erratic, Unpredictable Decisions Undermine Drug Regulation

The FDA keeps spinning, spinning, spinning round and round. Just what you want from a drug regulator: Erratic decision-making and complete unpredictability. https://t.co/q5abiPwgkW

By John Carroll
PET Scans Miss Cancer; System Needs Diagnostic Overhaul
SocialFeb 13, 2026

PET Scans Miss Cancer; System Needs Diagnostic Overhaul

Merkel cell carcinoma log, day #566. Completed my 6th PET scan at Dana-Farber yesterday. The radar, such as it is, doesn’t reflect any Merkel cell carcinoma. Lymph nodes look clean. The more I do PET scans, though, the more I...

By John Carroll
Sanofi's Board Ousts Hudson, New CEO Faces Dupixent Gap
SocialFeb 12, 2026

Sanofi's Board Ousts Hudson, New CEO Faces Dupixent Gap

So Sanofi's board strikes again. Paul Hudson gets the old Paris boot 6 years after taking on the task of remaking the pipeline. It hasn't gone well. Next: Belen Garijo. She has a few years to get ready for the...

By John Carroll
Biotech CEOs Dust Off S‑1s, Hopeful IPO Surge
SocialJan 9, 2026

Biotech CEOs Dust Off S‑1s, Hopeful IPO Surge

That blowing sound you hear is from hundreds of biotech ceos blowing the dust off their S-1s, fingers crossed.

By John Carroll
Predicting $20B+ Biotech M&A Deal by 2026
SocialJan 9, 2026

Predicting $20B+ Biotech M&A Deal by 2026

One of my #JPM26 predictions for 2026 is that we'll see a $20B-plus M&A deal in biotech. So here's hoping any RevMed deal comes after Monday morning. https://t.co/5pe4ymAILt

By John Carroll
Rampart's Fall Highlights Struggles in Legacy Gene Therapy
SocialJan 8, 2026

Rampart's Fall Highlights Struggles in Legacy Gene Therapy

Ryan's story notes that it's hard to tell exactly what killed Rampart. The faltering gene therapy field, specific scientific challenges, (any internal conflict). Maybe all of the above? No matter what, though, another sign of the cold wind blowing through...

By John Carroll