From Static Snapshots to Dynamic Protein Modeling
AlphaFold solved protein structure prediction. That's a snapshot. But biology isn't static. Proteins flex, shift, and interact across time. Drug targets have multiple conformations. Cells don't act alone. The next hard problem is capturing that motion, and building models that reflect how biology actually behaves, not just what it looks like frozen. @GabriCorso @boltz_bio just launched Boltz-2, which approaches FEP simulation accuracy for binding affinity prediction at over 1,000x the speed, with a @pfizer partnership announced this month. @Tkaraletsos co-founded @achira_ai for atomistic foundation models and spent years building virtual cell models at @ChanZuckerberg. Tanja Kortemme is Vice Dean of Research at @UCSF and one of the leading voices in computational protein design. Moderated by @ElliotHershberg of @AmplifyPartners. @SynBioBeta 2026 is May 4-7th in San Jose, California, you can learn more about the conference and get your tickets here: https://t.co/8abYWJ1GbK
Turning Down $10M Led to GitLab’s IPO Success
Sid Sijbrandij, co-founder of GitLab, was offered $10 million for his company. His dad said sell. His accountant said sell. His response: 'I really like working, so I don't mind working. And I think we can do better Six years later,...
Synthetic Biology Localizes Drug Production, Ending Fragile Supply Chains
Most pharmaceutical APIs still travel thousands of miles through fragile global supply chains before they reach a patient. COVID and the Russia-Ukraine war showed exactly what that fragility costs. Synthetic biology offers a different model: program cells to manufacture the molecules in...
30 Top Media Leaders at SynBioBeta Can Make You Viral
📰 𝟯𝟬 𝗝𝗼𝘂𝗿𝗻𝗮𝗹𝗶𝘀𝘁𝘀 𝗮𝗻𝗱 𝗣𝗿𝗲𝘀𝘀 𝗰𝗼𝗺𝗽𝗮𝗻𝗶𝗲𝘀 𝗮𝘁𝘁𝗲𝗻𝗱𝗶𝗻𝗴 𝗦𝘆𝗻𝗕𝗶𝗼𝗕𝗲𝘁𝗮 𝟮𝟬𝟮𝟲 𝘄𝗵𝗼 𝗰𝗼𝘂𝗹𝗱 𝗺𝗮𝗸𝗲 𝘆𝗼𝘂𝗿 𝗰𝗼𝗺𝗽𝗮𝗻𝘆 𝗴𝗼 𝘃𝗶𝗿𝗮𝗹 📰 With a combined reach of 500M+ monthly visitors, the journalists in the room at @SynBioBeta know how to get your work in front...
IPSC Tissues Supply Causal Data to Power Simulations
A general-purpose biological simulator, one that can predict how the human body responds to any intervention, isn't blocked by compute. It's blocked by data. Not data in general. Causal, human-relevant data. The kind where molecular interactions actually produce functional outcomes you...
Science Enables Viable Alternative to Inefficient Meat Production
For 12,000 years, we've been cycling crops through animals to make meat. It's one of the least efficient production systems on Earth, and also one of the most consequential: climate, deforestation, antibiotic resistance, pandemic risk. @BruceGFriedrich has spent a decade building the...
AI Designs Lab-Ready Antibodies From Text Prompts
Drug discovery has always meant finding. Screening libraries. Keeping what survives. Semiconductors don't work that way. Neither do aircraft. You design them computationally before anything gets built. @saakohl left @GoogleDeepMind after co-developing AlphaFold2 to do the same thing for biologics. @LatentLabs_ Latent-X2...
Today's Teen Could Become First 150‑year‑old
David Sinclair says the first person to live to 150 is a teenager who's alive today. He's taken flak from colleagues for years over this prediction. He doesn't care. He still stands by it. "The first person to live to 150 has...
AI Models Map Worm Brain, Scale to Synthetic Biology
The C. elegans nervous system has exactly 302 neurons and 7,000 synaptic connections. Scientists have had the full wiring diagram since 1986. What they haven't had: a computational model that captures how those neurons actually develop and wire themselves up. Eric Wasiolek...
Data, Not Models, Limits AI in Biology
The biggest bottleneck in AI for biology isn't models. It's data. @BerkeleyLab is building the infrastructure to fix that: integrated multi-omics datasets, queryable data lakehouses across data types, and high-quality annotated training data for modeling dynamic biological systems. This is DOE-funded, national-scale...
RNA‑seq No Longer a Bottleneck: 3‑day Turnaround
What if sequencing wasn’t the bottleneck anymore? #SynBioBeta2026 is May 4-7th in San Jose, California, you can learn more about the conference and get your tickets here: https://t.co/8abYWJ18mc @plasmidsaurus is removing friction from RNA-seq. 3-day turnaround in Europe. No dry ice. This is...
Physics‑Based Sensors and AI Transform Bioreactor Monitoring
Bioreactors are billion-dollar processes monitored by pH probes and dissolved oxygen sensors. That's like running a semiconductor fab with a thermometer. @schmidtsciences is adapting physics tools that don't usually touch biology: fluorescent nanodiamonds, single-cell Raman spectroscopy, and optical frequency combs that...
Genetically Switched Microbes Aim to Cut Synthetic Nitrogen Use
Nitrogen fertilizer feeds 4 billion people. It also uses 2% of global energy to produce and loses nearly half of what's applied to runoff. Biology has promised a fix for decades. The problem: engineered microbes that make nitrogen can't also compete...
Continuous Fermentation Cuts Costs, Beats Traditional Bioreactors
The biomanufacturing bottleneck isn't biology. It's economics. Building bigger bioreactors doesn't fix unit costs. https://t.co/2RAcw704uk's bet: continuous fermentation decouples growth from production, keeps cells in an ultra-productive state for weeks, and runs like a conveyor belt instead of a batch process. ...
One Engineer + AI Agents Replace Seven-Person Teams
Sid Sijbrandij, the co-founder of GitLab, just said: "One developer with parallel AI agents will outproduce an entire team of seven." And at his new company Kilo, that's already the standard. He has 20 engineers. Each one manages multiple AI agents across...
