Mike Thompson, MD PhD

Mike Thompson, MD PhD

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Oncologist/clinical researcher; trial commentary

Identifying Key Barriers to Boost Myeloma Trial Enrollment
SocialFeb 25, 2026

Identifying Key Barriers to Boost Myeloma Trial Enrollment

Identification of Significant Barriers to Accrual (BtA) to @theNCI Sponsored Multiple Myeloma – Clinical Trials (MM-CT): A Step towards Improving Accrual to #ClinicalTrials - @mweissmdphd et al. #ASH12 Abstract 3165 https://t.co/i4zO7ktqHJ #mmsm #caxtx #ctsm

By Mike Thompson, MD PhD
Quadruplet Therapy Effective without Early Transplant in NDMM
SocialFeb 25, 2026

Quadruplet Therapy Effective without Early Transplant in NDMM

#EAOnc EQUATE EAA181 Effective Quadruplet Utilization After Tx Evaluation: Ph3 RCT NDMM Not Intended for Early ASCT [Activated: 10/27/20] PI= @myelomaMD https://t.co/qD26HMx3J8 #NCT04566328 #mmMRD #mmsm @eaonc @mweissmdphd @VincentRK @LynneWagnerPhD Wei Snyder Kostakoglu @mtmdphd

By Mike Thompson, MD PhD
Phase 3 Trial Tests Daratumumab Regimens for New AL Amylo
SocialFeb 25, 2026

Phase 3 Trial Tests Daratumumab Regimens for New AL Amylo

.@SWOG S2213 Ph3 RCT Dara-VC Induction Followed by ASCT or Dara-VCD Consolidation & Daratumumab Maintenance in Pts w/ Newly Diagnosed AL Amyloidosis [Activated: 12/1/23] https://t.co/OizUfJCc2c #mmsm #bmtsm https://t.co/uikUnnJd3n

By Mike Thompson, MD PhD
New Guidelines Define Prior Therapy Lines in Multiple Myeloma
SocialFeb 25, 2026

New Guidelines Define Prior Therapy Lines in Multiple Myeloma

Guidelines for determination of the number of prior lines of therapy in multiple myeloma [Aug 13, 2015] @VincentRK , Richardson, San Miguel @BloodJournal https://t.co/Tdmr2gTUi6 #mmsm #ctsm #ClinicalTrials https://t.co/ZOobout75Q

By Mike Thompson, MD PhD
PI‑Rd Triplets Show Superior Efficacy And
SocialFeb 25, 2026

PI‑Rd Triplets Show Superior Efficacy And

Comparative Effectiveness and Safety of PI-Rd Triplets in Relapsed/Refractory Multiple Myeloma: INSIGHT-MM Data Analysis [Jan 13, 2026] @NoemiPuigM et al. European Journal of Haematology https://t.co/Vf7USecLlR #NCT02761187 #mmsm #openaccess https://t.co/C5Ya6TTQfo

By Mike Thompson, MD PhD
Hepta‑refractory Myeloma Arises via Sequential CD38
SocialFeb 24, 2026

Hepta‑refractory Myeloma Arises via Sequential CD38

The evolution to hepta-refractory myeloma involves sequential loss of CD38, BCMA and GPRC5D [Feb 17, 2026] Riedhammer et al. @LeukemiaJnl https://t.co/EyGBz7sEQz #mmsm #PrecisionMedicine #caxtx

By Mike Thompson, MD PhD
Doctor-in-the-Loop AI Enh
SocialFeb 23, 2026

Doctor-in-the-Loop AI Enh

Evaluating a doctor-in-the-loop AI-agent for multiple myeloma chart reviews [Nov 3, 2025] Karla Mariana Castro Bórquez et al. @HealthTree #ASH25 abs25-15262 PID 4424 https://t.co/MvBeHqOxCg #mmsm #AI #EMR #RWD https://t.co/onY817NfVr

By Mike Thompson, MD PhD
Histopathology Genomics Predicts Myeloma Risk in 1,429 Patients
SocialFeb 23, 2026

Histopathology Genomics Predicts Myeloma Risk in 1,429 Patients

Individualized treatment risk stratification using histopathology-based genomics prediction in multiple myeloma: A multicenter Study in 1429 participants [Nov 3, 2025] Rajanna et al. @DrOlaLandgren #ASH25 abs25-11635 PID 4008 https://t.co/gOprMCjfgh #mmsm #AI #oncopath https://t.co/pjikEsgfHC

By Mike Thompson, MD PhD
Race‑agnostic AI Accurately Predicts M‑protein in Myeloma
SocialFeb 23, 2026

Race‑agnostic AI Accurately Predicts M‑protein in Myeloma

Race agnostic models maintain accuracy in predicting M-protein levels in multiple myeloma [Nov 3, 2025] @rahul2u et al. #ASH25 abs25-11347 PID 2810 https://t.co/A27ozBoW8h #mmsm #AI #CancerDisparities https://t.co/ubJ6NGMFUE

By Mike Thompson, MD PhD
Unstructured Serum Data Hinders AI in Myeloma Care
SocialFeb 23, 2026

Unstructured Serum Data Hinders AI in Myeloma Care

Unstructured serum electrophoresis data limits real world AI models in multiple myeloma: Evaluation of 384 institutions across United States [Nov 3, 2025] @MalekEhsanMD et al. #ASH25 abs25-11278 PID 2809 https://t.co/mAC8l7xnaG #mmsm #cancerdisparities #hpeonc https://t.co/veJxBV5S0N

By Mike Thompson, MD PhD
Patients Favor Step‑Up Dosing for Teclistamab, Talquetamab
SocialFeb 23, 2026

Patients Favor Step‑Up Dosing for Teclistamab, Talquetamab

Patient perspectives & preferences for step-up dosing and treatment w/ teclistamab & talquetamab: Insights from a patient survey [Nov 3, 2025] @JayHydren et al. @RahulBanerjeeMD abs25-8335 PID 6354 https://t.co/pRlflaSb2I #mmsm #Tcellrx @HealthTree https://t.co/3I9nwsxZMx

By Mike Thompson, MD PhD
Patient‑Centered Registry Accelerates Multiple Myeloma Care
SocialFeb 23, 2026

Patient‑Centered Registry Accelerates Multiple Myeloma Care

The HealthTree Cure Hub registry: A patient-centered, multicenter approach to advancing multiple myeloma care - Jorge Arturo Hurtado Martínez et al. @HealthTree #ASCO25 Abst e19569 https://t.co/X2pdaIDYth #mmsm

By Mike Thompson, MD PhD
Most Myeloma Patients Prefer Shared Decision‑Making
SocialFeb 23, 2026

Most Myeloma Patients Prefer Shared Decision‑Making

Patient Preferences on Clinical Decision-Making in Myeloma: A 747-Patient Survey [Dec 7, 2024] @ManniMD1 et al. - @HealthTree https://t.co/jATJRKEfB2 #ASH24 Abst 2281 #mmsm HT @Taxkourel

By Mike Thompson, MD PhD
Side Effect Severity Shapes Patient Autonomy in Myeloma Care
SocialFeb 23, 2026

Side Effect Severity Shapes Patient Autonomy in Myeloma Care

Patient-Centered Care in Hematology: How Side Effect Severity Influences Decision-Making Autonomy in Relapsed Refractory Multiple Myeloma [Dec 8, 2024] Martinez et al. #ASH24 Abst 706 https://t.co/l7SHPBwbna #mmsm HT @Taxkourel

By Mike Thompson, MD PhD
Strong Care Team Ties Shape Myeloma Treatment Choices
SocialFeb 23, 2026

Strong Care Team Ties Shape Myeloma Treatment Choices

The effect of care team-patient relationship on decision-making in relapsed/refractory multiple myeloma - @MyelomaTeacher et al. @HealthTree #ASCO24 Abstract e19530 https://t.co/Ss5LZHH0Oj #mmsm

By Mike Thompson, MD PhD
Patients Reveal Hopeful Views on Myeloma Cure
SocialFeb 23, 2026

Patients Reveal Hopeful Views on Myeloma Cure

A survey on the patient perspective on cure in multiple myeloma [Oct 9, 2022] @ManniMD1 et al. @HealthtreeMM @TheLancetHaem https://t.co/1XhKT7AWGi #mmsm

By Mike Thompson, MD PhD
Patient‑Driven Platform Accelerates Multiple Myeloma Research
SocialFeb 23, 2026

Patient‑Driven Platform Accelerates Multiple Myeloma Research

.@HealthtreeMM Hub: A Patient-Derived, Patient-Driven Clinical Cancer Information Platform Used to Overcome Hurdles & Accelerate Research in Multiple Myeloma [3/10/22] @NSweeneyPhd @AhlstromJenny @FaithEDavies1 @mtmdphd @JCOCCI_ASCO https://t.co/WOwLb9Eozv @myelomacrowd #mmsm https://t.co/dZzhU3N32Q

By Mike Thompson, MD PhD
Patient Portal Streamlines Myeloma Imaging and Pathology Reporting
SocialFeb 23, 2026

Patient Portal Streamlines Myeloma Imaging and Pathology Reporting

. @HealthtreeMM Patient Portal mediated myeloma patient reported diagnostic imaging and pathology testing - @NSweeneyPhd @AhlstromJenny @mtmdphd J Clin Oncol 38: 2020 (suppl; abstr e20565) #ASCO20 https://t.co/CRLXETpeMm #mmsm #oncorad #oncopath https://t.co/m1UGDimLWm

By Mike Thompson, MD PhD
Low‑dose Dexamethasone Improves Survival in Newly Diagnosed Myeloma
SocialFeb 23, 2026

Low‑dose Dexamethasone Improves Survival in Newly Diagnosed Myeloma

Lenalidomide + high-dose dexamethasone (RD) vs lenalidomide + low-dose dexamethasone (Rd) as initial therapy for newly diagnosed multiple myeloma: an open-label RCT [10/22/2009] @VincentRK et al. @TheLancetOncol https://t.co/hXxlFINejC #NCT00098475 #EAonc E4A03 #mmsm #caxtx #ctsm https://t.co/FjBnt6yIox

By Mike Thompson, MD PhD
Daratumumab Boosts Revlimid Efficacy in Smoldering Myeloma
SocialFeb 23, 2026

Daratumumab Boosts Revlimid Efficacy in Smoldering Myeloma

#EAonc EAA173 - Daratumumab to Enhance Therapeutic Effectiveness of Revlimid in Smoldering Myeloma (DETER-SMM) - PI: @nsc_natalie https://t.co/VtBMJUjI5X Activated: Apr 30, 2019 #mmsm @eaonc #NCT03937635 @VincentRK @mweissmdphd https://t.co/QdWETmSoiR

By Mike Thompson, MD PhD
New Trial Compares Dara‑Bor‑Dex vs Cy‑Bor‑Dex for Myeloma‑Induced Kidney Damage
SocialFeb 23, 2026

New Trial Compares Dara‑Bor‑Dex vs Cy‑Bor‑Dex for Myeloma‑Induced Kidney Damage

EAA241 - Ph 2 RCT Dara-Bor-Dex vs Cy-Bor-Dex in the treatment of Newly Diagnosed Multiple Myeloma with Light Chain Cast Nephropathy (LCCN) [Study activated 8/11/25] @keruakous https://t.co/1NgvVZ3fTA #NCT07085728 #mmsm @eaonc https://t.co/paGRlHV1Dv

By Mike Thompson, MD PhD
Teclistamab‑Daratumumab Shows Strong Benefit in RRMM
SocialFeb 21, 2026

Teclistamab‑Daratumumab Shows Strong Benefit in RRMM

Teclistamab–Daratumumab in Relapsed or Refractory Multiple Myeloma [Feb 18, 2026] @End_myeloma et al. @NEJM https://t.co/PTSmdrV2zp #mmsm #tcellrx #ImmunoOnc QUICK TAKES: New phase 3 trial results are summarized in a short video.

By Mike Thompson, MD PhD
Exposure‑Response Guides Belantamab Dose in RR‑MM
SocialFeb 21, 2026

Exposure‑Response Guides Belantamab Dose in RR‑MM

Exposure–Response Analyses for Therapeutic Dose Selection of Belantamab Mafodotin in Patients with Relapsed/Refractory Multiple Myeloma [Sep 1, 2021] Ferron-Brady et al. Clinical Pharmacology & Therapeutics https://t.co/58kmDFKRwO #mmsm #oncopharm #caxtx

By Mike Thompson, MD PhD
BCMA Targeting Advances Multiple Myeloma Treatment Landscape
SocialFeb 21, 2026

BCMA Targeting Advances Multiple Myeloma Treatment Landscape

Targeting BCMA in Multiple Myeloma [Aug 25, 2021] Tan & @UrviShahMD Current Hematologic Malignancy Reports https://t.co/lAhqwwa7u3 #mmsm #caxtx #CARTcell

By Mike Thompson, MD PhD
Anti‑BCMA CAR‑T Triggers Immunoglobulin Isotype Switching
SocialFeb 21, 2026

Anti‑BCMA CAR‑T Triggers Immunoglobulin Isotype Switching

Immunoglobulin Isotype Switch after Anti-BCMA CAR T-Cell Therapy for Relapsed or Refractory Multiple Myeloma [Nov 10, 2021] Liang et al. @BloodAdvances https://t.co/KfreDCvIDH #CARTcell #mmsm https://t.co/7qNQBEoqkX

By Mike Thompson, MD PhD
Antigen Escape Drives Resistance to BCMA Therapies
SocialFeb 21, 2026

Antigen Escape Drives Resistance to BCMA Therapies

Antigen escape as a shared mechanism of resistance to BCMA-directed therapies in multiple myeloma [Jul 25, 2024] @RossFirestone et al. @BloodJournal https://t.co/cOh0YC2u9H #mmsm #ImmunoOnc #CARTcell #PrecisionMedicine #lymphoidneoplasia #immunobiologyandimmunotherapy https://t.co/6sbEv5KtLY

By Mike Thompson, MD PhD