Buried SSRI Failures Double Reported Efficacy Rates.
This was crazy. Burying failed SSRI trials. Published findings positive in ~100% vs 50% if they included the buried ones. Imagine reaction to bias like this psychedelic trials?! Tmk, no buried trials in psychedelic medicine. https://t.co/oRzHnk7mKu
New Survey Explores Psychedelic Trip Experiences Everywhere
Dear Anyone and Everyone, Planning a trip anywhere and anytime in any way? Check out this Carhart-Harris Lab/UCSF survey study: https://t.co/ZhZbWTtMLQ https://t.co/sdPLjrbr0L
Gamma Oscillations Reveal Brain's Entropic Signal Diversity
Gamma carries 'entropic brain' phenomena. In @elife: Spectrally and temporally resolved estimation of neural signal diversity https://t.co/MHFDILtuJa https://t.co/BxVcBL0gxA
More Prep, Fewer Depressive Symptoms in Psychedelic Therapy
More psychological prep, better outcomes: Psychological Therapy Quantity and Depressive Symptoms in Psychedelic Therapy https://t.co/akdzksV59W
Third Trial Shows No Expectancy Effect in Psychedelic Medicine
Just seen third replication of lack of expectancy to response prediction in psychedelic medicine trial. That’s 3/3 of my last 3 trials. Why won’t other teams test and report on this? See 2 new trials coming soon that replicate null...
Psychedelics Boost Brain Plasticity for Mental Health
On the meaning of ‘plasticity’ in neuroscience and mental health research and its relation to the action of psychedelic therapy https://t.co/63C34zf6mn via @OsfFramework
LSD Triggers Region‑Specific White Matter Plastic
Curious. Opposite DTI/FA findings to those we recently published on. Region specific? Neuroplastic white matter changes in patients with major depression following lysergic acid diethylamide treatment: Cell Reports Medicine https://t.co/sIXRAZumie
New Study Reveals Why Psychedelics Alter Minds Forever
After turning on to psychedelics, some say they are never the same again— Why? —No one knows... until now...? https://t.co/BuAU1vrn3P
Scientists Edge Closer to Mapping Psychedelic Brain Effects
Science gets closer to understanding how a psychedelic trip changes the brain https://t.co/XWKXo1TIAL via @nbcnews
Psychedelic Use Linked to Reduced Authoritarian Attitudes
Effects of psychedelic use on authoritarian attitudes revisited - Otto Simonsson, Taylor Lyons, Joseph Marks, Hannes Kettner, Leor Roseman, Eline Haijen, Mendel Kaelen, Robin Carhart-Harris, 2026 https://t.co/MeywBpE3CL
First Psychedelic Experience Alters Human Brain Structure
Very big paper dropping this Tuesday… watch this space… tell your gran… tell your neighbours… “Human brain changes after first psychedelic use” - Nature Communications…
Long‑time Applicants Finally See Chance for Rigorous Testing
Been applying to her office and others (eg welcome trust, nimh, arpa) for years asking to test/demonstrate that this isn’t magical thinking or snake oil. Glad to see things might change.
Weekly Psil
Big up Eric et al for driving this: Observing the mind under psychedelics: conceptual metaphors used following four once-weekly macrodoses of psilocybin https://t.co/gPYGMNkep0
Emotional Breakthrough Reaffirms as Top Response Predictor
Pleased to be included in this work. Emotional breakthrough as a strong predictor of response (again): https://t.co/pAPCipfd1U
Restarting SSRIs Improves Outcomes Over Med‑Free Approach
When we published our H2H in @NEJM Ian Jordan raised an excellent letter re SSRI discontinuation & how it might impact response. We looked & found he was right. Those who discontinued SSRIs and went back on (escitalopram) did far...