AI Lab Aims to Automate Its Own Creation
A new AI lab built from the ground up around automated research. Led by the legend Jerry Tworek, former VP of Research at OpenAI, where he led the development of reasoning models. Absolutely incredible founding team. Heavy hitters out of OAI, Anthropic, DeepMind. Core idea: scaling models, data, and static deployment won't get us to the promised land. We need something different: new learning algos, new architectures, and systems that automate the process of building itself. As they say, they're "pursuing new learning algorithms that supersede large-scale pretraining and reinforcement learning, and architectures that scale better than transformers." An AI to build AI.
Ron Conway’s Relentless Founder Support Sets the Standard
No better display of who @RonConway is than this: "While I will be stepping back from some of my usual activities, I will continue to support SV Angel founders, who I love with a passion." Even during his own struggles, he still...
Lithium Extraction Scales 350M× in 2.5 Years
This is what engineering progress looks like. @ElectroflowTech has scaled up their lithium extraction tech over 350M× since we backed them. In 2.5 years. First photo is the founders and the initial cell. Second shows the first 100K× scale up. Last ones...
Direct Action Forces Immediate Policy Change
When supply chains shut down in 2021, @typesfast rented a boat, hit the water, and tweeted what he saw in the Port of LA. The mayor changed the law that same day. On Progress, we get into tariffs, Black Death, AI...
Frontier AI Self‑Improves Safety, Paving Path to Future
Using frontier AI to autonomously improve safety and alignment capabilities is one of the best paths to a bright future.
NASA Releases Moon Base Guide for Permanent Off‑world Living
NASA just quietly published something incredible. A map of how we build a permanent human presence off Earth. It’s called the Moon Base User’s Guide. Here's what's in it! 🧵 https://t.co/oMEKKo5O8Q
Multiplexed In‑Vivo Screening Drives Next‑Gen Drug Development
Multiplexed in vivo screening is the future of drug development. @ManifoldBio is multiplexing protein therapies in vivo. @GordianBio is multiplexing gene therapies in vivo. @waypointbio is multiplexing cell therapies in vivo. GT Bio is multiplexing LNPs in vivo. 50Y portcos all https://t.co/DT2AwXbKtB
Automation Now as Critical as Product Development for Founders
Automating your company is becoming as important as building a great product. We held an AI for Founders workshop for our portfolio founders with tips and tricks from the 50Y dev team. Here are the highlights: https://t.co/scHbhpGx67 https://t.co/DzKUbjSw2R
Verification, Not Intelligence, Limits AI; Automate Everything
Two interesting points: AI is bottlenecked as much by verification as by intelligence. Big unlock is making correctness cheap to check for messy, high stakes reasoning via auditable flows. Today automating your company is just as important as building great product.
Treasury Urges Banks to Adopt Anthropic’s Powerful AI
A model so good the Treasury Secretary is making sure bank CEOs know about its capabilities to prevent catastrophe. Any sane government would want to be first in line to use this. But this administration is ostracizing the company that makes...
Scientists Should Build, Not Just Publish, Breakthroughs
Every scientist faces the same choice after a breakthrough: 1/ publish and move on 2/ build a startup to bring the breakthrough into the world David Kingham of @TokamakEnergy thinks the choice is clear: Build. https://t.co/7CDfmP90Yf
Iran War Prep, UK Drift, China Gains: US Crisis
Devastating frontpage for America. 1/ Iran preparing for prolonged war 2/ UK leaning away from US alliance 3/ strength in China's bond market due to the Iran war What a disaster. https://t.co/XMURlfO7uv
FCC Chair Turns Partisan, Threatening Democratic Media Freedom
The FCC Chair is at a partisan conference cheering journalists critical of the administration getting fired and allies buying news networks. The FCC should never be an arm of any political party. That’s how democracy dies.
AI Workflows Turn Months Into Weeks for Builders
With AI workflows it's often possible to do the work of many months in a single week. There's no better time to be a builder. But staying on top of the latest and greatest is hard. So we hosted an AI for...
Hackathon Targets Neural Repair, AI Surgery, Cryo Innovations
DEFEATING ENTROPY hackathon at @fiftyyears London HQ. Focus areas: Biomaterials for neural repair Engineered neural cells Tissue replacement AI for surgical robotics Advanced cryo methods Biostasis https://t.co/gMDDoo6Io4