Duplicated Genes Diverge over Time Under Weak Selection
After 30+ years of genetic drift with only weak selective pressure, a duplicated gene sequence will begin to look less and less like its original version. https://t.co/IAvCT3fn2t
Rapid Lab Automation Needed to Scale Bio Testing
Interesting take on lab automation and serial scale vs parallel scale for data generation. Innovation in how we can rapidly Test more and more in the lab is badly needed as Design, Build and Learn capabilities in bio have exploded...
Human Cells Lag Far Behind Yeast in Large DNA Integration
“Ultra large” in this paper is 8 kb 😭 > shows how far we are from achieving the sort of SynBio we routinely do in yeast in primary human cells. 50 kb integrations are fairly routine in yeast
Software Update Frenzy Mirrors AI Model Hype
Everyone suddenly being asked to update all their software and operating systems is going to be the ‘pizza orders near the pentagon’ for major new AI models isn’t it? https://t.co/aHFPp01TiH
Are These Insects Polymer‑Preserved Fossils?
What's the odds that these were just normal sized insects that died in a swellable polymer? Like expansion microscopy but for fossils.
Marc Guell’s SynBio Lab Featured in Journal’s 30‑Year Highlights
Great to see the SynBio work of @marcguellc lab getting featured as one of the highlights of 30 years of the journal
Prioritize Affinity, Specificity, Then Stability in Nanobody Design
Okay here's a game - you're making nanobody therapeutics. AI can help you optimise them, but you need to prioritise order of feature importance. What is your order? Affinity Specificity Expressibility Clinical toxicity In vivo stability Purified stability Patentability Other?
Vote for the Top Engineered Yeast Bioart
It’s time for the annual vote for best engineered yeast bioart from the @ImperialBioeng undergrad #SynBio students. Help us decide among these beautiful final 4 with your votes. 🗳️ ⬇️ https://t.co/2fo1XaGCmL
Aging: Tired Ribosomes Pause, Causing Us to Slow
If all of life is just ribosomes making more ribosomes, then maybe ageing is just old ribosomes getting tired and pausing, causing me to get tired and pause more often.
Finding Calm at VISTEC's Global SynBio Symposium
Back at peaceful campus of VISTEC 🇹🇭 all this week for their SynBio/Biocatalysis symposium with speakers from around the world. Nice to escape the heat and hustle of Bangkok. https://t.co/s9ZRM3uyDu
We All Ingest GMO Carbon From the Atmosphere
Can anything really be “GMO-free” these days? The answer is definitely no. A significant % of all atmospheric CO2 was made by GMO crops in the last 30 yrs, and these molecules cycles back into all plants and into your...
Future Oranges May Come with Built‑in Biodegradable Packaging
One day in the future our plant scientists will engineer oranges to have their own biodegradable packaging. Until then… https://t.co/IpqaTyuiJN
Record-Breaking Audience of Bacterial Cellulose Experts at Chulalongkorn Seminar
Was great to give a seminar today to the Dept. Food Technology at @ChulalongkornU University, Bangkok 🇹🇭 I present regulary on our lab's work on engineered materials based on bacterial cellulose (BC), but I think today breaks the record for the...
New Engineered Living Materials Advance Synthetic Biology
It’s not AI, JPM or anything to do with the Bay Area so probably no-one left on this site cares, but here is some new #synbio Engineered Living Materials work from our lab @ImperialBioeng and the Hub for Biotech in...
Bacterial Phenotypes Stay Robust Despite Massive Genome Reshuffling
Creating bacterial genomic diversity through large-scale reconfigurations reveals phenotype robustness to organizational genome change https://t.co/TiY6WNWjUm
