AI's Renaissance Awaits Our Choice of Fourth Pillar
1/ Get this moment right and you get Renaissance Florence. Get it wrong and you get the New Soviet Man —and the twenty million graves that came with him. AI is a Renaissance. Three of its four pillars are already here. The fourth is on us.🧵
Inner Life Becomes Humanity’s Edge Over Empty AI
“The inner life is the only competitive advantage left.” is vastly under appreciated. It points to the new role of human value in a world of amazingly competent but “internally” empty AI doers.
New AI‑Focused Medical School Opens in Santa Clara
Brand new med school (itself quite a feat) in Santa Clara, specializing in AI + healthcare delivery
AI Feels Like Modern Dial‑up, Full‑duplex Finally Arrives
Very cool demo for sure. But this reminds me even more of AI is the modern dialup. We’re back to reading text at 300 baud. And today the big innovation is full duplex.
Don’t Let Money and Fame Replace Your True Purpose
This is the biggest mistake I've seen great people make -- they get on a path to do great things, then the means (building a big company, making $$$) becomes the new ends, and people get lost in the dollars...
Only Adaptable, Hands‑on Leaders Survive in Agent-Driven Work
Strong agree -- "The two types of people that will not survive are pure people managers, and people that are rigid and don't want to change and evolve." A ton of managers couldn't do the work of their direct reports and...
AI Grant Tools Spark Endless Competitive Arms Race
Given the number of grants don’t increase with this AI grant writing tool, it seems like this all becomes an arms race to use the tools over your competitors, at best before they do. This is a common trend with AI...
Even Skeptics See AI's Unsettling Future in Sex Robots
Doomers: AI will destroy humanity Me: That’s self-serving, cash grabbing pessimism not rooted in reality [watches sex robot demo video] Me: ok, the Doomers may have a point on that one
Founders Battle Inner Pain, Not Just Hustle
Most people have no idea how hard it is to be a founder. And it’s not about work ethic or grinding or IQ. It’s about managing your own psyche against the relentless pain of failures inherent in going 0 to...
The Obvious Answer: Sears Needed Amazon‑style E‑commerce
Reminds me of early 2000’s questions like “Why can’t Sears just build a website like Amazon?” It’s the right question and the correct answer is a lot easier in hindsight.
AI Mirrors Your Drive: Amplifies Effort or Laziness
Like other tools, AI amplifies what you want and who you are. Hard working people will use it to do more. Lazy people will use it to avoid work. Curious people will use it to learn more. Insecure people will...
Growth Must Outpace Hype for Sustainable Investment
With any private investor froth, it's always a race for the company to grow into its valuation with business with sustainable economics before reality hits and ends the party. That's when the market reluctantly turns from speculation to investing.
AI-Driven Biology Could Slash Drug Trial Failures Dramatically
AI for biology will have bigger near term wins. The ability for AI to learn from experiments and predict human biology will have very broad impacts in predicting targets, clinical trials, and precision medicine. Tackling the biggest challenge in Pharma (80%...
Apple Metal Direct Inference Threatens NVIDIA's Software Moat
1/ It's amazing to see consumer hardware do inference on gigantic models, but that's not the big deal. @danveloper went straight to the Apple metal with Claude help, circumventing all the frameworks. NVIDIA's software moat may be now easily breakable, via ......
Truth Now Measured by Clicks, Not Accuracy
100% — as if it’s been trained to mostly just keep you happy and tell you what you want to hear. Ever since Google’s creation, the right answer (formally known as “truth”) was defined as what the user would click...