
The Andreessen Horowitz (a16z) Podcast discusses tech and culture trends, news, and the future as “software eats the world.” It features industry experts, entrepreneurs, and investors (often a16z partners) exploring topics in startups, VC, and emerging technology markets. Multiple episodes per week cover everything from venture funding insights to deep tech trends.

In this episode, Joe Weisenthal and Tracy Alloway interview David George, head of growth at Andreessen Horowitz, about the massive $5 trillion private tech market and why the most high‑growth companies are staying private longer. George explains that deeper, more liquid private capital, reduced regulatory burdens, and innovative employee liquidity mechanisms like tender offers make staying private attractive, while public markets now favor larger caps and impose costly compliance. He highlights that private‑market giants such as SpaceX, Databricks, Stripe, OpenAI and others represent a power‑law share of this valuation, and that hyper‑growth firms are hard to find among public stocks. The discussion also touches on the shift in compensation dynamics and the evolving outlook for future mega‑IPOs.

In this WSJ Invest Live episode, Andy Serwer interviews a16z general partner Katherine Boyle about the firm’s American Dynamism practice, which she launched to focus on defense and national‑security tech. They explore how openly championing "America" sparked debate in Silicon...

In this episode, a16z partner Jorge Conde interviews Novartis CEO Vasant Narasimhan about reshaping the 250‑year‑old conglomerate into a focused medicines company, a move he estimates will unlock $180 billion of value. Narasimhan outlines Novartis’s three platform pillars—cell and gene therapies,...

In this episode, a16z partner Joel de la Garza talks with Keycard CEO Ian Livingstone about the rapid shift from AI copilots to fully autonomous agents expected in 2026, and why enterprises will be the first adopters. They explore the...