
a16z Podcast
The Andreessen Horowitz (a16z) Podcast discusses tech and culture trends, news, and the future as “software eats the world.” It features industry experts, entrepreneurs, and investors (often a16z partners) exploring topics in startups, VC, and emerging technology markets. Multiple episodes per week cover everything from venture funding insights to deep tech trends.

Building AI Agents for Enterprise Operations
In this episode, Anisha Charya and Olivia Moore interview Happy Robot founders Pablo Palafox and Luis Parra about their voice‑AI platform that powers enterprise agents for logistics and other complex operations. They explain how voice was the initial hook for automating tasks like freight negotiation, but the real breakthrough lies in coordinating fragmented information across systems, handling noisy real‑world calls, and embedding deterministic guardrails to prevent AI hallucinations. The founders detail their technology stack—fine‑tuned LLMs, proxy servers, and tool‑calling workflows—that enables agents to orchestrate multi‑step processes such as tracking shipments, negotiating rates, and large‑scale collections. Their perspective highlights that successful AI deployment in enterprises requires not just smarter models but robust context layers and reliable execution across diverse use cases.

Stablecoins, AI Agents, and The Future of Global Banking
In this episode, a16z partner Angela Strange talks with Dalip Tasman, founder and CEO of Jeeves, about how the company is building a stablecoin‑native financial operating system for global enterprises. Tasman explains Jeeves' rapid growth—10x revenue and 8x volume—driven by...

Marc Rowan on Private Markets, Software Repricing, and Capital Allocation
In this episode, Marc Rowan, co‑founder of Apollo Global Management, discusses the evolution of private markets, the firm’s shift from distressed investing to a trillion‑dollar alternative‑asset powerhouse, and the massive capital needs of AI, robotics, energy infrastructure and data centers....

Why AI Isn’t Killing SaaS Yet
In this episode, hosts Jack Farley and Max Wheatley talk with Ramp lead economist Ara Karazian about the myth of a "SaaSpocalypse" driven by AI. Karazian explains that real business spend data shows seat‑based SaaS contracts still dominate (65‑75% of...

Hugging Face's Clem Delangue on Open Source AI and the LLM Bubble | MTS Live
Clem Delangue, CEO of Hugging Face, discusses the vital role of open‑source AI in fostering innovation and competition, contrasting the U.S.'s recent shift toward closed‑source LLM APIs with China's surge in open‑source contributions. He argues that the current hype around...

The Plan to Make American Crime Obsolete
In this episode, Colonel Jeffrey Glover and Rahul Sidhu discuss how emerging technologies—especially drones, AI-driven analytics, license‑plate readers, and body‑camera insights—are reshaping American law enforcement and public safety. They highlight real‑world deployments that improve response times, de‑escalate incidents, and monitor...

Ben Horowitz - "Your ONLY Job Is Right Product, Right Time"
In this A16Z Speedrun talk, Ben Horowitz stresses that a founder’s sole responsibility is delivering the right product at the right time, and that everything else—hiring, fundraising, storytelling— serves that core goal. He argues that a clear, written "company story"...

Energy, Minerals, and the Physical Stack Behind AI
In this episode, Turner Caldwell of Mariana Minerals and Drew Begalino of Heron Power discuss how America’s AI and industrial future depends on revamping the physical stack of critical minerals, energy generation, and grid infrastructure. They explain their Tesla‑inspired, software‑first...

Marc Andreessen on Builder Culture in the Age of AI
In this episode, Marc Andreessen and host Eric discuss how AI is shifting from hype to core infrastructure, dramatically boosting productivity and spawning a new class of "super‑producers." They examine the paradox of AI fear and hype, citing the Anthropic...

The New Space Race: NASA, Artemis, and the Race to the Moon
In this episode, NASA Administrator Jared Isaacman outlines the agency’s aggressive push to accelerate Artemis moon missions, shifting launch cadence from years to months and rebuilding core in‑house competencies. He emphasizes the strategic importance of a sustained lunar presence for...

Building Blackstone, Backing Costco, with Tony James
In this episode, David Haber interviews Tony James, a veteran of DLJ and Blackstone, about the evolution of modern private markets and the principles behind building enduring firms. James recounts how DLJ grew from a tiny boutique to a top‑five...

Sarah Rogers: Free Speech, AI Diplomacy, and What America Owes Its Allies
In this episode, Undersecretary of State Sarah B. Rogers discusses how public diplomacy now centers on defending free speech and digital freedom abroad, reversing the previous administration’s content‑removal efforts. She argues that a "Western AI stack"—AI built on individualistic, consent‑based,...

Balaji and Taylor Lorenz on AI and Media
In this episode, Balaji Srinivasan and tech journalist Taylor Lorenz discuss how AI is reshaping media, trust, and the economics of information. They argue that AI-generated content makes verification harder, prompting a push for cryptographic truth, decentralized identity, and human‑only...

John and Patrick Collison on Stripe's Growth, Agent Commerce, and the Future of Software
In this episode, Stripe co‑founders John and Patrick Collison discuss Stripe's rapid growth—processing over $1 trillion in payments and expanding 34% year‑over‑year—and the emerging wave of "agentic commerce" powered by AI and stablecoins. They argue that future commerce will require blockchains...

Ben Horowitz on Venture Capital and AI
In this Stanford CS153 talk, Ben Horowitz, co‑founder of Andreessen Horowitz, explains how his firm reinvented venture‑capital structure to better serve entrepreneurs as software reshaped markets. He describes centralizing decision‑making, scaling the firm into small, focused teams, and building a...