a16z Podcast
The Andreessen Horowitz (a16z) Podcast discusses tech and culture trends, news, and the future as “software eats the world.” It features industry experts, entrepreneurs, and investors (often a16z partners) exploring topics in startups, VC, and emerging technology markets. Multiple episodes per week cover everything from venture funding insights to deep tech trends.
Technology, Culture, and the Next AI Interface with Signüll
In this episode, A16Z partner Anish Acharya chats with the enigmatic online commentator known as Signal about the accelerating convergence of technology, culture, and AI personalities. They explore how AI’s growing power—especially through agents and model "personality" development—remains primitive and inaccessible for most users, and argue that making AI cheap, brief, and intuitive is key to broader adoption. Signal reflects on the rapid pace of tech change, the gap between formal knowledge and tacit intuition, and how creators should focus on passion and fun rather than purely technical hype. The conversation also touches on the future of AI-driven relationships, the "stone‑age" state of everyday AI use, and the differing archetypes of modern founders.
Building Agents at Home: Parenting, Work, and Benevolent Neglect
In this episode, former Y Combinator founder and homeschooling mother Jessie Janais explains how she leveraged AI agents to automate household and educational tasks, ultimately allowing her to spend focused time with her four young children while still building tech....
Who Controls AI Acceleration? Vitalik Buterin and Guillaume Verdon Debate
In this episode, A16Z Crypto’s Eddie Lazarin moderates a deep dive into AI acceleration philosophies with Ethereum founder Vitalik Buterin, Extropic CEO Guillaume Verdon, and Shaw Walters. They contrast Effective Accelerationism (EAC), which argues that accelerating AI development is essential...
Alex Blania on Proof of Human and Building World's Identity Network
In this episode, Alex Banya, co‑founder and CEO of World, explains the emerging "Proof of Human" challenge—how to verify that online interactions are truly from unique humans rather than AI bots or agents. He outlines why traditional methods like government...
What Happens When a Public Company Goes All In on AI
In this episode, a16z partner David Haper talks with Owen Jennings, Block’s executive officer, about the company’s bold decision to cut roughly 40% of its workforce and reorganize around AI‑driven small squads. Jennings explains how breakthroughs in large‑language‑model coding tools...
The SpaceX and Tesla Playbook for Hard Tech Startups
In this episode, Erin Price‑Wright talks with Chandler Lujica, CEO of Galadine (next‑generation missile propulsion), and Turner Caldwell, CEO of Mariana Minerals (critical mineral supply chains) about how their time at SpaceX and Tesla shaped the way they build hard‑tech...
Security, Resilience, and the Future of Mobile Infrastructure
The episode explores the massive security breach known as Salt Typhoon, which gave China access to U.S. cellular networks, and discusses how the Navy and a startup called CAPE are building a resilient, secure mobile infrastructure that can operate over...
Submarines and the Future of Defense Manufacturing
In this episode, Vice Admiral Robert Goucher, the Pentagon’s first “submarine czar,” and Chris Power, CEO of Hadrian, discuss the urgent need to rebuild the U.S. submarine fleet and the massive workforce gap threatening that effort. They explain how submarines...
The Missing Power Layer of Modern Warfare
In this episode, Adam Wormuth, CEO of Chariot Defense, and Army CTO Alex Miller discuss the critical "missing power layer" needed for modern, distributed electronic warfare. They explain how today’s soldiers rely on 30‑60 watts continuously, and how existing diesel...
AI, Supply Chains, and the Future of Economic Power
In this episode, Jacob Helberg, Undersecretary of State for Economic Affairs, discusses how AI, hardware, and secure supply chains have become central to U.S. economic and national security. He outlines the administration’s three‑front strategy to win the AI race: superior...
What's Missing Between LLMs and AGI - Vishal Misra & Martin Casado
In this episode, Martin Casado interviews Vishal Misra, a Columbia professor who has built a mathematical model of how large language models (LLMs) operate, treating them as massive sparse matrices that update token probabilities via Bayesian-like inference. Misra explains his...
Emil Michael: Iran, Anthropic and the Future of AI at the Pentagon
Emil Michael, Undersecretary of Defense for Research and Engineering, explains how he streamlined the Pentagon’s technology priorities from 14 vague areas to six, placing applied AI at the top. Within 90 days, AI usage surged from 80,000 to 1.2 million personnel,...
What It Takes to Clear a Million Crimes a Year with Flock Safety's CEO
In this episode, Garrett Langley, CEO of Flock Safety, explains how his company transformed neighborhood security by deploying license‑plate‑reading cameras, AI‑driven analytics, and drones that integrate with 911 calls to create a real‑time crime‑clearance operating system. He recounts the origin...
Chris Dixon: From Quant Trading to Building A16z Crypto
In this episode, Chris Dixon recounts his journey from a self‑taught programmer in the 1980s to a quant developer, serial entrepreneur, and now a General Partner at Andreessen Horowitz leading its crypto practice. He shares insights from founding SiteAdvisor, an...
When Giants Don’t Go Public: Inside the $5 Trillion Private Tech Market
In this episode, Joe Weisenthal and Tracy Alloway interview David George, head of growth at Andreessen Horowitz, about the massive $5 trillion private tech market and why the most high‑growth companies are staying private longer. George explains that deeper, more liquid...