NIH-Funded AI Model Predicts Cancer Survival From Single-Cell Tumor Data
Researchers at Oregon Health & Science University, funded by the NIH, unveiled scSurvival, an AI model that predicts cancer patient survival from single‑cell tumor data. The tool was evaluated on clinical datasets from more than 150 melanoma and liver cancer patients and demonstrated higher accuracy than conventional bulk‑averaging approaches. By assigning survival‑related weights to individual cells, scSurvival also identifies the specific immune and tumor cell populations that drive risk. The study highlights the potential of cellular‑resolution analytics to refine prognostic assessments and therapeutic targeting.
Dr. Jonathan M. Green Selected as CEO of the NIH Clinical Center
Dr. Jonathan M. Green, M.D., MBA, has been appointed CEO of the NIH Clinical Center, the world’s largest hospital dedicated to clinical research, effective May 17, 2026. He will oversee a 200‑bed, 870,000‑square‑foot facility with an annual operating budget of roughly $700 million....
Low-Cost Care Model Reduces Blood Pressure in High-Risk Populations
A NIH‑funded trial tested a scalable, team‑based care model in 36 federally qualified health centers in Louisiana and Mississippi. The intervention, which combined intensive blood‑pressure management, home monitoring, health coaching and provider feedback, lowered systolic blood pressure by more than...
NIH Awards Top Scientific Teams for Innovations Linking Nutrition and Autoimmune Disease
The National Institutes of Health announced 15 winning teams in its Nutrition for Our Immune System Health (NOURISH) Autoimmunity Challenge, each receiving a $10,000 prize. The challenge solicited scalable, patient‑centered ideas that integrate diet, microbiome, and multi‑omics approaches to study...
Dr. Elisabeth Armstrong Named NIH Chief of Staff
The National Institutes of Health announced Dr. Elisabeth Armstrong as its new chief of staff, bringing a blend of public‑sector leadership and private‑sector insight. Previously the director of the FDA’s Office of the Executive Secretariat, she oversaw agency‑wide information flows...
NIH Invests $150 Million in Human-Based Research to Reduce Use of Animal Models
The National Institutes of Health announced a $150 million investment in the new Complement‑ARIE program to develop and standardize human‑focused research tools, known as new approach methodologies (NAMs). The initiative will fund technology development centers, a data hub, and a validation...
Clinical Trial Results Support Use of Weekly Extended-Release Buprenorphine for Treatment of Opioid Use Disorder During Pregnancy
A NIH‑backed multicenter trial of 140 pregnant adults found that weekly injectable extended‑release buprenorphine achieved significantly higher rates of illicit opioid abstinence than daily sublingual buprenorphine, while also reducing serious maternal adverse events. The study, published in JAMA Internal Medicine,...
Researchers Develop AI Tool to Predict Patients at Risk of Intimate Partner Violence
Researchers funded by the NIH have created an AI‑driven clinical decision support tool that predicts intimate partner violence (IPV) risk using both structured health records and unstructured medical notes. In a study of 850 IPV cases and 5,200 matched controls,...
Automated CT Scan Analysis Could Fast-Track Clinical Assessments
NIH‑funded researchers at Stanford introduced Merlin, a foundation model that interprets 3D abdominal CT scans for a broad spectrum of clinical tasks. Trained on more than 15,000 scans paired with radiology reports and nearly one million diagnostic codes, Merlin outperformed specialist...
A Fresh Energy Supply May Shield Nerves From Diabetic or Chemo-Induced Neuropathy
Researchers funded by the NIH discovered that satellite glial cells (SGCs) deliver mitochondria to sensory neurons through tunneling nanotubes, a process essential for neuronal energy supply. In mouse models of diabetes and chemotherapy‑induced neuropathy, this mitochondrial transfer is impaired, leading...
Researchers Achieve the First Minimally Invasive Coronary Artery Bypass
Researchers at NIH and Emory have performed the world’s first minimally invasive coronary artery bypass, called VECTOR, without opening the chest. The technique reroutes blood flow by creating a new coronary ostium using catheter‑based tools introduced through the femoral vessels....
NIH Halts Arm of Clinical Trial Evaluating a Potential Stroke Treatment
The National Institutes of Health halted the low‑dose rivaroxaban arm of the CAPTIVA trial after the Data Safety and Monitoring Board identified a rise in adverse events and concluded the treatment was unlikely to be beneficial. CAPTIVA, a double‑blind, three‑arm...
NIH-Funded Study Clearly Ties Risk of Dementia to Severe CTE
A new NIH‑funded study provides the strongest evidence linking severe chronic traumatic encephalopathy (CTE) to dementia risk. Analyzing 614 donated brains without Alzheimer’s or other common neurodegenerative diseases, researchers found stage IV CTE patients were 4.5 times more likely to have...
NIH Scientists Develop "Digital Twin" Of Eye Cells to Understand and Treat Age-Related Macular Degeneration
NIH researchers have built the first subcellular‑resolution digital twin of human retinal pigment epithelial (RPE) cells, using 3‑D imaging of 1.3 million cells and an AI algorithm called POLARIS. The model maps polarity, organelle size and volume across developmental stages, creating...
NIH Proposes Embryonic Stem Cell Research Shift to Put Patients First
The National Institutes of Health announced a Request for Information aimed at identifying biotechnologies that can replace human embryonic stem cells (hESCs) in research. NIH is temporarily pausing the review and approval of new hESC lines, leaving the existing 503...