
Dr. David Carmouche, Lumeris: Why AI Is Primary Care's Best Chance at Survival
In this episode, Christina Farr talks with Dr. David Carmouche, Chief Medical and Commercial Officer at Lumeris, about the crisis in primary care and how AI could be its lifeline. Carmouche explains that rising administrative burdens, outdated fee‑for‑service payment models, and patient consumerism have eroded the traditional doctor‑patient relationship, leaving PCPs overwhelmed and patients disengaged. He argues that autonomous AI—combined with new payment structures that reward outcomes rather than visits—could enable a single primary‑care physician to effectively manage thousands of patients, restoring efficiency and joy to the profession. Carmouche also highlights ongoing federal and state experiments, such as CMS’s Access Model and state sandbox initiatives, that are testing these innovative payment and care‑delivery frameworks.

How SaaS Is Evolving From Software to AI Solutions | Artera's Guillaume De Zwirek & Dan Goldsmith
In this episode, Guillaume de Zwirek, CEO of Artera, and board member Dan Goldsmith discuss how AI is reshaping SaaS into a hybrid of bespoke services and software, especially in healthcare. They argue that the old engineering‑centric, product‑first mindset is...

Why Price Transparency Took a Decade to Crack | Heather Fernandez, Solv
In this episode, Heather Fernandez, CEO of Solve, discusses the decade‑long struggle to achieve price transparency in U.S. healthcare and how her company is finally cracking the "how much will it cost me?" question using AI-driven ClearPay. She traces her...

Behind Kalshi’s $22B Rise: Betting on Addiction with Dr. Rian Kabir
In this episode of Lifers, host Christina Farr talks with psychiatrist and medical AI specialist Dr. Rian Kabir about the rapid rise of online prediction marketplace Kalshi, now valued at $22 billion. Dr. Kabir explains that, despite legal arguments framing Kalshi...

Building Maven Clinic when No One Believed with CEO Kate Ryder
In this episode of Lifers, CEO Kate Ryder discusses the evolution of Maven Clinic, the first unicorn in women's health, focusing on the challenges of scaling from $200M to $500M in revenue and aligning every part of the business. She...

Dr. Oliver Kharraz on the Decades-Long Journey to Make Scheduling a Doctor's Appointment Easier
In this episode, Christina Farr talks with Oliver Kharraz, CEO of Zocdoc, about the 15‑year quest to simplify doctor appointment scheduling. Kharraz explains how hidden appointment inventory and last‑minute cancellations can be leveraged as a matchmaking clearinghouse, and recounts early...
![[Emergency Pod] Peptides - Part 1 with Sunita Mohanty of Ultralight](/cdn-cgi/image/width=1200,quality=75,format=auto,fit=cover/https://megaphone.imgix.net/podcasts/d0db1eda-2c6f-11ef-958d-9fb4aba9c1ce/image/0bfc12f76c8a92fdb53253e1c884033d.jpg?ixlib=rails-4.3.1&max-w=3000&max-h=3000&fit=crop&auto=format,compress)
[Emergency Pod] Peptides - Part 1 with Sunita Mohanty of Ultralight
In this episode of Lifers, host Christina Farr talks with Sunita Mohanty, CEO and co‑founder of Ultralight, about the booming interest in peptide therapies for wellness and longevity. Sunita explains that while peptides are gaining popularity—driven by anecdotal success, recent...

Is Healthcare Safe From the SaaS Bloodbath? With Omada CEO Sean Duffy and Stephanie Davis
In this episode of Lifers, host Christina Farr talks with Omada Health CEO Sean Duffy and equities analyst Stephanie Davis about whether the current SaaS market downturn, driven by AI hype and tightening valuations, threatens digital health firms. Duffy explains...

President of Microsoft Science Saw ChatGPT Coming (and Now He Predicts How It Will Change Healthcare) | Peter Lee
In this episode, Peter Lee, President of Microsoft Research, recounts the evolution of AI from early neural networks to today’s large language models, describing how Microsoft recognized OpenAI’s potential early on and invested heavily despite industry skepticism. He explains the...

Othman Laraki, Color CEO, on Surviving Three Major Pivots
In this episode, Othman Laraki, CEO of Color, recounts the company’s three major pivots—from a cancer genetics startup to its current health‑tech platform—highlighting the financial, team, and market challenges each transition entailed. He stresses that while technology and product are...