E680 | Oskar Hartmann, Accumulator: From Beast Mode to a New Angel Investing Model
In this episode, Andreas Munk Holm talks with Oskar Hartmann, a serial founder turned super‑angel, about his "beast mode" approach, burnout lessons, and the importance of product‑soul fit. Hartmann explains the new Accumulator model—a share‑pooling mechanism that gives founders and angels liquidity while diversifying risk, aiming to create deca‑ and hectocorn companies in Europe. He also shares insights from his global experience, especially in India, and stresses that community‑driven investing can mitigate adverse selection and concentration risk.
E679 | This Week in European Tech with Dan, Mads & Lomax
In this episode Dan Bowyer, Mads Jensen, and Lomax Ward dissect a range of power shifts across European tech, from OpenAI’s health‑focused ChatGPT and the FDA’s fast‑track AI medical device approvals to Meta’s acquisition of AI‑agent platform Manus and Nvidia’s...
20Growth: The $6.6B Growth Engine Behind ElevenLabs | Why ElevenLabs Do Not Have PMs | The 7 Part Launch Playbook to Crush All Launches with Luke Harries, Head of Growth @ ElevenLabs
In this episode, Luke Harries, Head of Growth at ElevenLabs, breaks down the company’s $6.6 billion growth engine, detailing how a horizontal product strategy and sharded growth teams drive massive scale. He shares a 7‑part launch playbook that routinely generates 700K+...
Howard Lutnick: How America Can Hit 6% GDP Growth in 2026
In this episode, Commerce Secretary Howard Lutnick outlines how strategic trade policies, revamped tech initiatives, and targeted reforms could propel U.S. GDP growth to 5‑6% by 2026. He discusses the legacy of Trump’s tariffs, the evolving US‑Japan trade relationship, stalled...
Data-Driven Science and Leadership
In this episode, Dominik Schumacher, CEO and co‑founder of Tubulis GmbH, explains how the company’s antibody‑drug conjugate (ADC) technology uniquely targets cancer cells, minimizing side effects and enhancing patient outcomes. He details the distinctive chemistry that sets Tubulis’s ADCs apart...
Episode 111: Jimmy Wales
In Episode 111, host discusses the evolution of online knowledge sharing with Wikipedia co‑founder Jimmy Wales, covering the platform’s impact on information accessibility, challenges around misinformation, and the future of open‑source collaboration. Wales shares insights on the balance between community...
Keycard: 2026 Is the Year of Agents
In this episode, a16z partner Joel de la Garza talks with Keycard CEO Ian Livingstone about the rapid shift from AI copilots to fully autonomous agents expected in 2026, and why enterprises will be the first adopters. They explore the...
The $800M Exit that Started with a Single Muffin
In this episode, Katlin Smith recounts how she turned a humble almond‑flour muffin experiment into Simple Mills, a clean‑snack brand that grew into a $800 million exit. She discusses the challenges of scaling a health‑focused food company, the strategic decisions that...
E677 | Michael Brehm, Redstone: One Investment, 200 Ventures — The New Blueprint for European VC Access
In this episode, Michael Brehm of Redstone explains how the firm backs a single investment across 200 European ventures, creating a new model for VC access that spreads risk and capital efficiently. He discusses the rationale behind concentrating capital, the...
VC10X - Gamification of Consumer Apps - Phylicia Koh, GP, Play Ventures
Phylicia Koh, GP at Play Ventures, explains how gaming mechanics are becoming the operating system for consumer apps, with in‑app purchases in non‑gaming sectors now outpacing traditional gaming spend. She outlines Play Ventures' $142 M thesis focused on "playable apps" that...
20VC: $0-$260M in Revenue in Three Years: How We Did It | You Need to Work Weekends to Win — Most Founders Aren't Ambitious Enough | The Revolut Playbook: Speed, Urgency, Extreme Ownership, and Zero Excuses with Alan Chang @ Fuse Energy
Alan Chang, co‑founder and CEO of Fuse Energy, shares how he scaled the company from $2M to $400M in three years by applying the same high‑speed, extreme‑ownership culture he helped build at Revolut. He emphasizes that building a generational business...
VC10X - Inside a $1.5 Billion Japanese Fund’s Big Bet on India - Rajeev Ranka, Partner, Incubate Fund
In this episode, Rajeev Ranka of Japan's Incubate Fund explains their 100‑year investment horizon and how it shapes decisions like backing Captain Fresh during COVID and pivoting it from a domestic brand to a global seafood exporter. He argues that...
VC10X Micro - BigTech Energy War - The Next Battleground for AI Race
The episode explains how the AI boom has shifted the competitive focus from chips to electricity, prompting Big Tech firms to acquire or contract power assets—Google’s $4.75 billion purchase of Intersect Power, Microsoft’s Three Mile Island restart, and Amazon’s nuclear deals. It highlights...
How to Unlock Your Team’s Creative Potential
In this episode, Reid Hoffman talks with former PepsiCo CEO Indra Nooyi about how to cultivate an environment that unlocks a team’s creative potential. Nooyi shares the leadership principles and talent‑development initiatives she implemented at PepsiCo, emphasizing psychological safety, clear...
Resurrecting Dire Wolves Is Just the Beginning for Colossal Biosciences’ Ben Lamm
In this Rapid Response encore, Ben Lamm, co‑founder and CEO of Colossal Biosciences, walks host Bob Safian through the company’s de‑extinction of the dire wolf, explaining the scientific process, the high‑profile investor backing, and the broader implications for conservation, biodiversity,...
Scott Bessent: Fixing the Fed, Tariffs for National Security, Solving Affordability in 2026
Treasury Secretary Scott Bessent outlines how tariffs can be wielded as a national‑security tool, despite legal hurdles, and argues that targeted tariffs could protect critical supply chains. He critiques the Federal Reserve’s past policies that fueled a 15‑year asset bubble,...
Legacy, Innovation, and the Future of ASEAN Agri-Food W/ Ho Ren Hua, CEO of Thai Wah PCL
In this episode, Sarah Chen‑Spellings talks with Ho Ren Hua, CEO of Thai Wah, about transforming a 77‑year‑old family starch business into a regional agri‑food and bio‑materials platform anchored in sustainability. He outlines the “F4” framework (Farm, Factory, Family, Food) and shows how...
The Present and Future of AI in Sales and GTM A Deep Dive with Jason Lemkin and Kyle Norton, CRO at Owner
Jason Lemkin and Owner CRO Kyle Norton discuss how AI agents now outperform average AEs and SDRs, reshaping GTM team structures. They stress that CROs/CMOs must personally train at least one agent within 30 days, choose one or two vendor...
Stefan Roebel: Building Europe’s New Defense Tech Prime
In this episode, Stefan Roebel, co‑founder and CEO of ARX Robotics, discusses how his company evolved from makeshift decoy robots to NATO‑backed modular systems now operating in Ukraine, illustrating the need for Europe to overhaul its slow defence procurement and...
VC10X - Stop Competing with Sequoia: Finding Alpha in Secondaries & Emerging Markets
In this episode, Maxim and Pavel of FinSight Ventures explain their "secondary‑first" approach, using secondary market purchases from employees and liquidity‑seeking funds to secure stakes in high‑growth companies like Anthropic, SpaceX, Stripe and Palantir, and they unveil a $50 million Generative...
Matthew Wilson (Jack & Jill) & Peter Specht (Creandum): AI Recruiting Agents, a $20M Seed & the New GTM Playbook
In this episode, Matthew Wilson of Jack & Jill and investor Peter Specht discuss how AI-driven recruiting agents are reshaping a broken talent market, highlighting the founding insight that voice‑based agents can create a high‑signal two‑sided marketplace. They explain Jack’s...
How Evan Spiegel Is Building the Future of Computing
In this episode, Evan Spiegel discusses Snap's decision to reject a $3 billion Facebook acquisition to preserve its independent culture and vision, and outlines the company's strategic pivot toward augmented‑reality glasses as the next growth frontier. He emphasizes the need for...
We Deployed 20+ AI Agents and Replaced Our Entire Human SDR Team. Here's What Actually Works. (Video + Pod)
In this episode the hosts detail how they replaced their human SDR team with over 20 AI agents, sending 60,000+ hyper‑personalized emails, booking 130+ meetings and generating 15% of SaaStr AI London ticket revenue by targeting low‑priority and ghosted leads....
20Growth: How Wiz Built a $30BN Brand in Enterprise | What Worked vs What Was a Mega Failure: Lessons Learned | Why Marketers Make the Worst CMOs & What To Look for in Growth with Raaz Herzberg
In this episode, Raaz Herzberg, CMO and VP of Product Strategy at Wiz, recounts the company's rapid rise from a ten‑person startup to a $30 billion enterprise brand, highlighting the unconventional marketing tactics and product‑led growth strategies that fueled its success....
VC10X Micro - Why Bond Yields Are Rising Again (And What It Means for Investors)
The episode explains why long‑term government bond yields are rising again in late 2025 despite central‑bank rate cuts, focusing on the 10‑year Treasury as a key benchmark. Higher yields increase the discount rate, pressuring valuations of long‑duration assets such as...
Sergey Jakimov, LongeVC: Impacting Lives Through Longevity & Health Investing
In this episode, Sergey Jakimov, co‑founder of LongeVC, explains the firm’s $1.6 trillion longevity market thesis, its AI‑enhanced deal sourcing, and the strong track record of Fund I (over 3x MOIC with zero write‑offs). He walks through three flagship investments—Insilico Medicine, Turn...
20VC OGs: SpaceX Valued at $800BN & Harvey Raises $160M at an $8BN Price | Airwallex Raises $330M and The Battle with Keith Rabois | Netflix Acquires Warner Brothers | IPO Market Predictions for 2026: Anthropic, Stripe, Databricks and SpaceX
The episode explores SpaceX’s $800 billion valuation and its implications, followed by forward‑looking IPO market forecasts for 2026, including potential listings for Anthropic, Stripe, Databricks, and SpaceX. It examines Netflix’s strategic acquisition of Warner Brothers, highlights major fundraising rounds such as Harvey’s...
Healthcare Predictions for 2026
In this episode, Siobhan Nolan Mangini, Bob Kocher, and Bryan Roberts review their 2026 healthcare forecasts, highlighting where their AI predictions have already proven accurate and outlining upcoming challenges such as inflation pressures and the controversial "TrumpRx" policy. They assess...
Charles Dunn & Ruth McKernan, SV Health Investors: Exit of the Year Winners and Biotech Company Builders
In this episode, Charles Dunn and Ruth McKernan of SV Health Investors discuss their hybrid model of creating biotech companies and making later‑stage venture investments, highlighting how this structure diversifies risk for LPs and enables cross‑stage learning. They showcase recent successes,...
This Week in European Tech with Dan, Mads & Lomax
The panel dissects Europe’s tech landscape, starting with Bending Spoons’ aggressive roll‑up strategy and the broader valuation reset driven by debt‑fuelled M&A and Italy’s PE‑VC hybrid model. They debate Brexit’s lingering economic fallout, the erosion of German automotive dominance, and...
The Pull to Build: Joubin Mirzadegan on Grit and Starting Roadrunner
In this episode, Joubin Mirzadegan discusses how his relentless discipline and frustration with broken infrastructure drove him to leave Kleiner Perkins and become CEO of Roadrunner, now a $7.2 billion company. He shares lessons from an early startup failure, emphasizing that...
What Comes After ChatGPT? The Mother of ImageNet Predicts The Future
Fei‑Fei Li and her former student Justin Johnson discuss their new model Marble, which creates explorable 3D worlds from text or images, highlighting how spatial intelligence differs fundamentally from language and why current world models lack physics understanding. They argue...
20VC: Inside Bending Spoons Acquisition Machine: Evernote, Eventbrite, Vimeo | How Evernote Evaluates Acquisitions and New Product Ideas | How Evernote Mastered Product Launches, User Retention and Monetisation with Federico Simionato
In this episode, Federico Simionato, a product lead at Bending Spoons, walks through the company’s rapid growth from a small game studio to an $11 billion acquisition powerhouse, sharing how they evaluate and test new product ideas and build a coveted...
The Psychology Every Founder Needs Right Now | A16z GP Reveals Secrets to Success
In this episode, a16z GP Anish Acharya explains why consumer tech is resurging, highlighting how AI now enables products to reach 100 million users at unprecedented speed. He outlines the distribution shifts and founder mindsets required for success through 2026, emphasizing...
He Launched a Tiny Ice Cream Factory, Now It’s a National Brand Ft. Alec Jaffe
In this episode, Mike Gelb talks with Alec Jaffe, founder and CEO of Alec’s Ice Cream, about creating a premium, gut‑friendly ice cream brand using A2 dairy and regenerative farming. Alec explains how he built a supply chain with family...
VC10X - Why Fundraising Is Now a Numbers Game (And How to Win) - Braughm Ricke, Founder, Aduro Advisors
In this episode, Braughm Ricke of Aduro Advisors explains how venture capital fundraising has shifted from relationship‑driven to a volume‑based numbers game, driven by data from over 650 firms managing $131 B+. He highlights the growing polarization between well‑capitalized “haves” and...
The $700 Billion AI Productivity Problem No One's Talking About
In this episode, Russ Fradin and a16z General Partner Alex Rampell argue that the $700 billion AI productivity gap stems from a lack of robust measurement infrastructure, similar to what drove the internet ad boom. They explain how companies struggle to...
Building Cloudflare for the Next 50 Years | Co-Founder Cloudfare Michelle Zatlyn
In this episode, co‑founder and President Michelle Zatlyn discusses Cloudflare’s long‑term vision for securing the internet and supporting creators in an AI‑driven landscape. She highlights how the company balances rapid growth with staying close to customer realities, and outlines strategies...
E660 | This Week in European Tech with Dan, Mads, Lomax & Robin
The episode dissects Europe’s tech climate, covering policy moves like EU child‑social‑media bans and UK startup‑friendly budget reforms, while highlighting regulatory friction exemplified by N26’s German battles and VAT compliance woes. Robin Haak provides insider perspective on Germany’s macro challenges—energy...
E658 | Martin Scherrer, Redstone VC: CVC Secondaries Without Burning Bridges
In this episode Martin Scherrer of Redstone VC explains how corporate venture arms can exit their investments through secondary sales or managed runoff without eroding value or relationships. He highlights the importance of treating CVCs as true portfolio managers—using proper...
Future-Proofing Portfolios W/ Chris Rynning (AMYP Ventures) & Anulika Malomo (HarbourVest Global Private Equity)
Chris Rynning and Anulika Malomo discuss how LPs, family offices, and GPs can future‑proof portfolios for 2025 and beyond, focusing on AI risk, liquidity crunches, and the fallout from China’s DeepSeek shock. They highlight the growing reliance on secondaries, new...
Season 14 Finale: The Mad Scientist, The Foxhole, and a $48M Power Move
The finale revisits four of the seven Napa pitches, providing deep‑dive updates on each founder’s progress and highlighting a dramatic $48 million acquisition that reshapes the competitive landscape. Listeners learn how one startup’s “mad scientist” approach to AI drove rapid product...
He Launched a Tiny Ice Cream Factory, Now It’s a National Brand Ft. Alec Jaffe
In this episode, Mike Gelb talks with Alec Jaffe, founder of Alec’s Ice Cream, about creating a premium, gut‑friendly ice cream brand using A2 dairy and regenerative sourcing. Alec explains how he built a farm‑to‑factory supply chain, differentiated real ice...
PE10X - Lessons From $4.7B in Software Growth Equity with Maitlan Cramer, MD Bow River Capital
Maitlan Cramer, Managing Director at Bow River Capital, explains how their "Capital Plus" playbook scales B2B SaaS firms by taking majority-control positions and actively fixing broken processes rather than just providing capital. He stresses choosing a large, healthy market over...
The 2045 Superintelligence Timeline: Epoch AI’s Data-Driven Forecast
Epoch AI researchers discuss a data‑driven timeline for superintelligence, arguing that Anthropic could build the first gigawatt‑scale AI datacenter and that breakthroughs like solving the Riemann hypothesis may arrive within five years. They challenge the notion of "energy bottlenecks," framing...
She Sold Her Startup for $500 Million, Here’s Her Next Idea
In this episode, Brynn Putnam discusses how her personal frustration with screen‑driven family disconnection inspired Board, a face‑to‑face gaming console designed to reunite families, and reflects on her previous ventures like Mirror that also emerged from personal needs. She emphasizes...
20VC: Base44's Maor Shlomo on How Vibe Coding Will Kill SaaS and Salesforce | Why It Is BS that Vibe Coding Platforms Do Not Have Defensibility and Bad Margins | Why He Worries About Google, Not Replit and Lovable | Why Long Anthropic, Not OpenAI?
Maor Shlomo, founder of Base44, argues that AI‑driven "vibe coding" platforms will disrupt traditional SaaS and CRM tools like Salesforce by offering faster, low‑code development with superior user experience. He challenges the notion that these platforms lack defensibility or margins,...
Epstein Files Fallout, Nvidia Risks, Burry's Bad Bet, Google's Breakthrough, Tether's Boom
The episode opens with a deep dive into the fallout from the Epstein files, focusing on the lingering questions about the source of his wealth. It then shifts to market dynamics, highlighting Tether's rapid growth, Michael Burry's contentious bet versus...
The Hot Mic: Should You Start a Venture Fund?
In this Hot Mic episode, three listeners pose their top questions to seasoned venture capitalists, who discuss whether starting a venture fund is advisable, the key criteria they use to evaluate pitches, and the one startup they wish they'd invested...
20VC: Max Altman on The New Seed War: Can Anyone Compete with Sequoia and A16z | Leaving $2BN on the Table with Reddit | Lessons From Backing Rippling at $25M Post | Why Climate Tech Is a Mirage and Disaster
Max Altman discusses the intensifying "seed war" where only giants like Sequoia and a16z can dominate early rounds, highlighting how many founders leave billions on the table by undervaluing deals such as Reddit's. He shares behind‑the‑scenes stories from backing Rippling...