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David Barzilai, MD PhD

David Barzilai, MD PhD

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Clinician focused on prevention/longevity; curates aging science and protocols.

AI Unlocks Treatments for Previously Incurable Diseases
Social•Mar 10, 2026

AI Unlocks Treatments for Previously Incurable Diseases

These diseases were thought to be incurable. Now AI is unlocking new treatments https://t.co/DyXpQQZKf2 https://t.co/rywFdtqS8Q

By David Barzilai, MD PhD
Time-Restricted Eating May Extend Healthy Lifespan
Social•Mar 10, 2026

Time-Restricted Eating May Extend Healthy Lifespan

Time-restricted eating as a potential strategy for healthy lifespan: an evaluation of current evidence https://t.co/wuXCFoZi1f https://t.co/mgFWzcFmSZ

By David Barzilai, MD PhD
Whole‑cell Cycle Simulation Demands Years, GPUs, Six Days
Social•Mar 10, 2026

Whole‑cell Cycle Simulation Demands Years, GPUs, Six Days

Why simulating an entire cell cycle took years, multiple GPUs and six days per run https://t.co/41xr8Bnn4C https://t.co/9LcRqDswYT

By David Barzilai, MD PhD
PCSK9 Drives Vascular Aging, Offers New Therapeutic Targets
Social•Mar 10, 2026

PCSK9 Drives Vascular Aging, Offers New Therapeutic Targets

PCSK9 in Vascular Aging and Age-Related Diseases Comprehensive summary of PCSK9's regulatory functions in vascular aging, highlighting potential therapeutic targets for combating age-related cardiovascular diseases. https://t.co/uo3PaSJLCb https://t.co/w8UZgIduPV

By David Barzilai, MD PhD
Aged Grandmothers Pass Metabolic Shifts to Grand‑Offspring Oocytes
Social•Mar 10, 2026

Aged Grandmothers Pass Metabolic Shifts to Grand‑Offspring Oocytes

Intergenerational Transmission of Metabolic Changes in Oocytes From Aged Mice 👉 “ Our findings indicate a remodelling of lipid homeostasis in oocytes of female mice derived from AMA great-grandmothers and highlight the need to take a closer look at the inheritance...

By David Barzilai, MD PhD
AI‑Driven Health Tools May Extend Lifespan to 100
Social•Mar 9, 2026

AI‑Driven Health Tools May Extend Lifespan to 100

How New Longevity Tech Could Help You Reach 100 Daily biometrics, smart scales and AI companions are quietly rewriting the rules of aging. https://t.co/lAmYntfSP5 https://t.co/YYo4tWkgMg

By David Barzilai, MD PhD
We Must Weigh TPE’s Microplastic Trade‑off Against Benefits
Social•Mar 9, 2026

We Must Weigh TPE’s Microplastic Trade‑off Against Benefits

Real question worth asking: does TPE remove more microplastics than it introduces? I have my doubts. That said, the animal data is compelling and deserves serious translational follow-up. Ultimately, it all comes down to quantifying risk versus benefit at the individual level👨‍⚕️...

By David Barzilai, MD PhD
Arrive Early: Build Reputation, Show Respect, Ensure Reliability
Social•Mar 9, 2026

Arrive Early: Build Reputation, Show Respect, Ensure Reliability

Better 15 minutes early than 5 minutes late. Reliability, respect for others, and your reputation matter more than the small advantage of arriving ‘just in time.’ 🦉

By David Barzilai, MD PhD
Mitochondrial Quality Control Drives Senolytic Resistance
Social•Mar 9, 2026

Mitochondrial Quality Control Drives Senolytic Resistance

Comparative analysis of senolytic drugs reveals mitochondrial determinants of efficacy and resistance "findings suggest that mitochondrial quality control is a key determinant of resistance to ABT263-induced and ARV825-induced senolysis, providing a possible framework for rational combination senotherapies." https://t.co/xB0wFkzIW9

By David Barzilai, MD PhD
Antibiotic‑induced Microbiome Depletion Revives Aging Brain Function
Social•Mar 8, 2026

Antibiotic‑induced Microbiome Depletion Revives Aging Brain Function

Microbiome depletion rejuvenates the aging brain 👉"We confirmed that antibiotic treatment improves vascular density, promotes myelination, enhances neurogenesis, and reduces microglial reactivity. Functionally, microbiome-depleted mice showed improved hippocampal memory performance." https://t.co/XYuJ2kPVbi

By David Barzilai, MD PhD
Lifestyle Choices Link to DNA Methylation Aging Rates
Social•Mar 8, 2026

Lifestyle Choices Link to DNA Methylation Aging Rates

Lifestyle factors and DNA methylation-based aging clocks: cross-sectional and longitudinal associations in the Singapore diet and healthy aging cohort https://t.co/x0zpRxwOXX

By David Barzilai, MD PhD
Key Modifiable Dementia Risks Identified in Norway Seniors
Social•Mar 8, 2026

Key Modifiable Dementia Risks Identified in Norway Seniors

Potentially modifiable risk factors for dementia in Norway (HUNT4 70+): a retrospective cohort study https://t.co/8DUSdzlf4e

By David Barzilai, MD PhD
Proliferation Stress Drives Human Stem Cell Aging
Social•Mar 8, 2026

Proliferation Stress Drives Human Stem Cell Aging

Molecular and phenotypic blueprint of human hematopoiesis links proliferation stress to stem cell aging https://t.co/3mjdKHKcPc

By David Barzilai, MD PhD
Creatine Modestly Boosts Adult Cognitive Performance,
Social•Mar 7, 2026

Creatine Modestly Boosts Adult Cognitive Performance,

The effects of creatine supplementation on cognitive function in adults: a systematic review and meta-analysis https://t.co/tLGUiinPPl

By David Barzilai, MD PhD
Time‑Restricted Feeding Fails to Boost Nutrient Intake in Elite Footballers
Social•Mar 7, 2026

Time‑Restricted Feeding Fails to Boost Nutrient Intake in Elite Footballers

The impact of time-restricted feeding on energy and macronutrient intake among elite Jordanian football players: a randomized controlled trial "TRF did not significantly improve energy or macronutrient intake compared to the standard diet. Both groups exhibited persistent energy and carbohydrate deficits...

By David Barzilai, MD PhD

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