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David Barzilai, MD PhD

David Barzilai, MD PhD

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Clinician focused on prevention/longevity; curates aging science and protocols.

Creatine Boosts Body, Brain, Strength, Sleep in Menopause
Social•Mar 7, 2026

Creatine Boosts Body, Brain, Strength, Sleep in Menopause

Impact of creatine supplementation on menopausal women’s body composition, cognition, estrogen, strength, and sleep https://t.co/8ZqpAr94uG

By David Barzilai, MD PhD
Ferroptosis Links Iron Imbalance to Age‑Related Muscle Loss
Social•Mar 7, 2026

Ferroptosis Links Iron Imbalance to Age‑Related Muscle Loss

Is Ferroptosis the Mechanistic Bridge Connecting Iron Dysregulation to Muscle Wasting and Functional Decline in Aging? https://t.co/Tg5ZSIfZB2 https://t.co/Tl6nluUA0s

By David Barzilai, MD PhD
Intermittent Fasting Offers Minimal Weight Loss Benefit, Evidence Uncertain
Social•Mar 7, 2026

Intermittent Fasting Offers Minimal Weight Loss Benefit, Evidence Uncertain

Intermittent fasting for adults with overweight or obesity "...Compared to regular dietary advice, intermittent fasting may result in little to no difference in weight loss or quality of life. Intermittent fasting may result in little to no difference in adverse events,...

By David Barzilai, MD PhD
Cryotherapy Boosts Metabolism and Hormones, Best for Higher BMI
Social•Mar 7, 2026

Cryotherapy Boosts Metabolism and Hormones, Best for Higher BMI

"A series of WBC sessions improved carbohydrate metabolism and modulated adipokine and sirtuin profiles, with the most pronounced effects observed in individuals with elevated BMI. However, this effect generally may require a longer treatment series." The effect of whole-body cryostimulation treatments...

By David Barzilai, MD PhD
Warmer Temperatures Linked to Higher Adult Obesity
Social•Mar 7, 2026

Warmer Temperatures Linked to Higher Adult Obesity

Ambient Temperature and Adult Obesity: Evidence from U.S. County-Level Panel Data "The results indicate that higher ambient temperatures are associated with higher adult obesity rates, even after accounting for correlated environmental conditions..." https://t.co/ewEuMdqr3O

By David Barzilai, MD PhD
Bright Light Therapy Boosts Glymphatic Flow and Prefrontal Activity
Social•Mar 7, 2026

Bright Light Therapy Boosts Glymphatic Flow and Prefrontal Activity

Bright light therapy influences glymphatic system function in individuals with subthreshold depression: a randomized clinical trial Highlights 👇👨🏻‍⚕️” 🔘 Bright light therapy (BLT) influences glymphatic function in subthreshold depression. 🔘 BLT enhanced brain functional activity of the prefrontal cortex. 🔘 BLT links glymphatic system...

By David Barzilai, MD PhD
Bitter Compounds Protect Brain in Diabetic Cognitive Decline
Social•Mar 7, 2026

Bitter Compounds Protect Brain in Diabetic Cognitive Decline

Bitter Compounds as Multifunctional Agents against Diabetes-associated Cognitive Dysfunction: Bridging Metabolic Regulation and Neuroprotection https://t.co/Xv3xItlP20

By David Barzilai, MD PhD
Naringenin Boosts Brain Longevity by Targeting Aging Hallmarks
Social•Mar 6, 2026

Naringenin Boosts Brain Longevity by Targeting Aging Hallmarks

Targeting aging hallmarks in brain health within the framework of preventive medicine: mechanistic insights into naringenin's role in longevity, synaptic function, and cellular homeostasis https://t.co/JPiEz5VnQe https://t.co/C0EYPRepwy

By David Barzilai, MD PhD
Aged and Alzheimer Brains Show Somatic Retrotransposition
Social•Mar 6, 2026

Aged and Alzheimer Brains Show Somatic Retrotransposition

Retrotransposon Activation in the Aged and Alzheimer’s Disease Brain Examined by Nanopore Long-read DNA Sequencing "...we report somatic retrotransposition events in the aging and demented brain..." https://t.co/zkRCMO1Plh

By David Barzilai, MD PhD
Sleep Masterclass: Expert Tips From Topol and Ju
Social•Mar 6, 2026

Sleep Masterclass: Expert Tips From Topol and Ju

A Master Class on Sleep, with plenty of practical tips Eric Topol with Guest Professor Yo-El Ju https://t.co/sKY9e7Tinq https://t.co/Gofntnw02o

By David Barzilai, MD PhD
Proanthocyanidins Show Promising Neuroprotective Mechanisms
Social•Mar 6, 2026

Proanthocyanidins Show Promising Neuroprotective Mechanisms

Advance in neuroprotective effects of proanthocyanidins (PCs): Structure, absorption, bioactivities, mechanism, and perspectives https://t.co/AMfxcjo4m6 https://t.co/oTMCLW0CKL

By David Barzilai, MD PhD
Healthspan Horizons: Federated AI Platform Makes Longevity Measurable
Social•Mar 6, 2026

Healthspan Horizons: Federated AI Platform Makes Longevity Measurable

Healthspan Horizons just launched out of the Buck Institute's Price Lab. It's a federated, privacy-preserving research platform aimed at making healthspan measurable and actionable through AI and systems science. The Flagship White Paper is worth a read👨‍⚕️ https://t.co/OoxuurRJNE | @BuckInstitute

By David Barzilai, MD PhD
Stem Cells Show Promise for Neurodegenerative Disease Treatment
Social•Mar 6, 2026

Stem Cells Show Promise for Neurodegenerative Disease Treatment

A narrative review on the therapeutic potential of stem cells in neurodegenerative diseases: advances, insights, and challenges 👉"Stem cell therapy offers regenerative potential for neurodegenerative diseases. 👉Mesenchymal stem cells (MSCs), induced pluripotent stem cells, and neural stem cells show promise through neuroprotection...

By David Barzilai, MD PhD
Targeting Autophagy May Extend Healthy Lifespan
Social•Mar 6, 2026

Targeting Autophagy May Extend Healthy Lifespan

Links between autophagy and healthy aging "Identification of autophagy modulators holds promise to improve healthspan..." https://t.co/PJjbfpeYTg https://t.co/tXreB5m4cw

By David Barzilai, MD PhD
Engineered IL-10 Boosts Neurogenesis and Cognition in Aging Brain
Social•Mar 6, 2026

Engineered IL-10 Boosts Neurogenesis and Cognition in Aging Brain

Targeting immune cells in the aged brain reveals that engineered cytokine IL-10 enhances neurogenesis and improves cognition @BrunetLab https://t.co/n9bsJPSJQT https://t.co/9vvH3eEU0e

By David Barzilai, MD PhD
Cranberry-Derived Ergostane Restores Ovarian Function in Mice
Social•Mar 6, 2026

Cranberry-Derived Ergostane Restores Ovarian Function in Mice

Ergostane steroid, as one of the major contributor to cranberry derived extracellular vesicle nanoparticles, restores ovarian function of murine premature ovarian failure https://t.co/CFcjDvzMnU https://t.co/le7VTHjEKa

By David Barzilai, MD PhD
Engineered Brain Cells Clear Dementia Plaques in Mice
Social•Mar 6, 2026

Engineered Brain Cells Clear Dementia Plaques in Mice

Boosted Brain Cells Erase Dementia-Linked Proteins “At nearly six months of age, when untreated mice normally have brains saturated with harmful plaques, brains of treated mice were plaque-free. Meanwhile, older mice with plaque-saturated brains at the time of treatment saw a...

By David Barzilai, MD PhD
Exercise and Enriched Settings Shield Brain Barrier From Depression
Social•Mar 6, 2026

Exercise and Enriched Settings Shield Brain Barrier From Depression

Exercise and enriched environments help protect brain barrier from stress-linked depression, finds study https://t.co/BcXFdEXP3f https://t.co/02j702A4Zq

By David Barzilai, MD PhD

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