David Barzilai, MD PhD

Year-Long Aerobic Exercise Preserves White Matter, Boosts Cognition

Effects of aerobic exercise and cardiorespiratory fitness on white matter free water fraction in older adults: a 1-year randomized controlled trial "These findings suggest that 1 year of aerobic training may reduce [Free Water Fraction] in the CC body and that higher physical fitness preserves white matter microstructure and support cognitive health in older adults." Protocol? 👇 "The program started with a frequency of three exercise sessions per week for 25–30 min per session at the intensity of 75–85% of the maximal heart rate measured during VO2max testing at baseline. Between weeks 11 and 25, participants began alternating between three and four exercise sessions per week for 30–35 min per session. During the weeks in which they performed three exercise sessions per week, a high-intensity exercise session was introduced which comprised 30 min of walking at the intensity of 85–90% of maximal heart rate (e.g., brisk uphill walking). After week 26, participants performed four to five exercise sessions per week for 30–40 min, including two high-intensity sessions..." https://t.co/FrxFgoaIKT