David Barzilai, MD PhD

David Barzilai, MD PhD

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Clinician focused on prevention/longevity; curates aging science and protocols.

APOE Ε2 Variant Boosts Longevity and Cognitive Resilience
SocialJun 17, 2026

APOE Ε2 Variant Boosts Longevity and Cognitive Resilience

Longevity and cognitive resilience in a Colombian family carrying the APOE ε2 variant https://t.co/NiDOqChNNB https://t.co/Pj6hV9t3zA

By David Barzilai, MD PhD
Sleep Decline Reveals Integrated Metabolic, Inflammatory, Circadian Aging
SocialJun 17, 2026

Sleep Decline Reveals Integrated Metabolic, Inflammatory, Circadian Aging

Sleep deterioration as a systems-level readout of aging biology: integrating metabolic, inflammatory and circadian mechanisms https://t.co/6G13bnNuK6 https://t.co/W6JIKN9DFP

By David Barzilai, MD PhD
AHA Outlines Lifelong Brain Health Research Framework
SocialJun 16, 2026

AHA Outlines Lifelong Brain Health Research Framework

Brain Health Across the Life Span: A Framework for Future Studies: A Scientific Statement From the American Heart Association https://t.co/kpiidSR2ev https://t.co/6wmbtm57SO

By David Barzilai, MD PhD
Mouse Cloning Shows Epigenetic Rejuvenation Limits Lifespan
SocialJun 16, 2026

Mouse Cloning Shows Epigenetic Rejuvenation Limits Lifespan

Why Epigenetic Rejuvenation Won't Give Us Radical Life Extension: Lessons from Serial Mouse Cloning Lessons from probably the most important longevity study in a decade By Peter Fedichev PhD @fedichev https://t.co/Y3Tbqs8xhK https://t.co/WsZCYL5Xfe

By David Barzilai, MD PhD
Mammals Need Sex to Remove Cloning‑Induced Genetic Errors
SocialJun 16, 2026

Mammals Need Sex to Remove Cloning‑Induced Genetic Errors

Limitations of serial cloning in mammals “…When re-cloned mice from near the final generation were mated with males, their oocytes could be fertilized, but most embryos degenerated…” [ 🔎 “…a few embryos were normalized by meiosis and fertilization and developed to full...

By David Barzilai, MD PhD
Strength Training May Slow Cellular Aging and Cancer
SocialJun 16, 2026

Strength Training May Slow Cellular Aging and Cancer

Exercise, Cellular Senescence, and Cancer: Novel Perspectives on Functional Aging Through Block Strength Training in Older Adults-A Narrative Review https://t.co/wjkeLxWTRF https://t.co/UDTemTXh4v

By David Barzilai, MD PhD
Cellular Aging Signatures in Blood Predict Disease Risk
SocialJun 16, 2026

Cellular Aging Signatures in Blood Predict Disease Risk

Plasma proteomic signatures of cellular aging predict human disease “🔘 We observed that 20–25% of individuals exhibited accelerated aging in a single cell type and 1–3% in 10 or more cell types. 🔘 Cellular aging signatures were associated with disease status...

By David Barzilai, MD PhD
Aging ECM Drives Senescent Cell Buildup and Persistence
SocialJun 16, 2026

Aging ECM Drives Senescent Cell Buildup and Persistence

The aging extracellular matrix as a missing link in senescent cell accumulation and persistence https://t.co/ENVIiUn0Dl https://t.co/mhznrNkFsX

By David Barzilai, MD PhD
Nanomedicine Targets Senescent Cells to Combat Aging
SocialJun 16, 2026

Nanomedicine Targets Senescent Cells to Combat Aging

Translational nanomedicine strategies for selective senescent cell clearance in aging and age-related diseases: a critical review https://t.co/fxuHAOkKSs

By David Barzilai, MD PhD
Life Bio Achieves First Clinical Milestone for OSK Therapy
SocialJun 16, 2026

Life Bio Achieves First Clinical Milestone for OSK Therapy

Life Bio reaches first clinical milestone for OSK therapy 🏥 “The longevity field has spent much of the past decade debating whether aging can be modified at the level of cellular identity itself. Now, one of the sector’s most closely watched...

By David Barzilai, MD PhD
Extreme Age Phenotypes Uncover Shared Longevity Pathways
SocialJun 16, 2026

Extreme Age Phenotypes Uncover Shared Longevity Pathways

Decoding human longevity: Genetic and molecular insights from accelerated to successful ageing 👉 Extreme phenotypes reveal convergent pathways across ageing trajectories. https://t.co/RcgWPrGuoV https://t.co/CAxiFP4f4a

By David Barzilai, MD PhD
UAE's $8 Trillion Healthy‑Ageing Market Opens Investment Opportunities
SocialJun 15, 2026

UAE's $8 Trillion Healthy‑Ageing Market Opens Investment Opportunities

Dubai Longevity Authority: Investment opportunities in UAE’s $8 trillion healthy ageing market 💫"We firmly believe that every scientific breakthrough should deliver tangible benefits to people's lives, and that serving humanity will always remain the ultimate purpose of every investment in science,...

By David Barzilai, MD PhD
AI Uncovers Peptide Structures for Healthy Aging
SocialJun 15, 2026

AI Uncovers Peptide Structures for Healthy Aging

Dietary geroprotective peptides: structural determinants, AI-driven discovery, and synthetic biology production for healthy ageing https://t.co/ihAsC3PVJM https://t.co/3aogpRk97I

By David Barzilai, MD PhD
Low Vitamin D Fuels Inflammation, Heightens Motoric Cognitive Risk
SocialJun 15, 2026

Low Vitamin D Fuels Inflammation, Heightens Motoric Cognitive Risk

Vitamin D, systemic inflammation, and motoric cognitive risk: exploring the risk factors and mediation pathways https://t.co/0SjbPdiwwR

By David Barzilai, MD PhD
David Barzilai, MD PhD | Pulse