Wearable Health Data Needs Integration; DIY Solutions Lead
Google Health/Fitbit vs Whoop is gonna be a heck of a fight $100-300 a year for these products is tiny price to pay for the massive gains you get from them If only doctors and medical record companies and these devices played nicely together Right now the best option is to simply “roll your own” solution Eightsleep, Function/superpower, Oura/whoop/fitbit, peptides, glps etc Healthcare is the place AI could turn its reputation around
VCs Forecast War’s Impact on Supply Chains
What are top VCs telling their portcos about the war in the middle east? Today on TWiST’s VC roundtable, we got a look at how industry insiders think about the war. When will it end? What are the most important...
VC Concentration Surge Raises Questions for 2026 Founders
Is venture capital dead? Many argue that the concentration of capital, like we’re seeing right now, could mean the end of the industry. 5 firms committed 73% of all LP commits in Q1 this year… What does this mean for...
VC Returns Rarely Beat Indexes, Retail Investing Risky
People think of VC as this gold rush where once you’re on the inside, you’re set, you’re loaded for life. The truth is that most VC funds don’t actually make money, certainly not enough to outperform something like the S&P....
Media Bias Undermines Trust in Safer Self-Driving Cars
Statistically, self-driving cars are safer than human drivers. So why do most people still not trust them? Is it because humans fear this type of technology change? Or is it because of narratives being pushed by the media? Michael Eisenberg...
Pronoun Politics Cost a Team Member’s Tenure
Had someone at one of my companies using pronouns in their communications, and I was like, "dude, you know this looks immature and silly to 90% of our partners." He quit a couple of months later.
J‑Curve Shows Investment Leads
The JCurve is perhaps the most wonderful chart in all of life Invest, invest, invest… harvest, harvest, harvest. American Exceptionalism Manifest https://t.co/WKtJ4gFB1H
Switch to Podcasting for Massive Growth and Ownership
You lose nothing... because no one is watching late-night TV anymore. @StephenAtHome will instantly have a top 100 podcast and get 5-10x the viewership -- if he has the guts to do it he will also own 100% of his...
Quarterly Liquidity Bridges VC Lock‑Up Gap for Retail
Most venture funds lock your money up for 10 years. Historically, the big issue with bringing these types of investments to the masses is that retail investors aren’t willing to have their funds locked up for that long. In comes...
USVC Opens Startup Investing to Everyone with $500
In 2026 you can buy any shitcoin you want. You can bet on Polymarket for how long Trump shakes someone's hand. All perfectly legal. But investing in a startup? Accreditation wall. Apparently retail investors can’t be trusted to invest in...
Blocked Merger Proves Free Market Limits, Spirit Fails
You think you understand free markets better than the free markets operate. You're wrong. Spirit airlines has gone under. Recall that in 2024, Spirit’s merger with Jetblue was blocked. And now here we are… Looking at another bankrupted business that...
Netflix Needs a Dedicated LIVE Tab for Live Shows
It's literally impossible to find a live show like @billsimmons on @netflix -- @reedhastings @sarandos_ted Just put a LIVE tab up top OR when you search for the word "LIVE" show the.... ummm.... live shows?
Anthropic May Overtake Bitcoin Market Cap by Year-End
This Polymarket, “Will Anthropic’s market cap flip BTC by Dec 31?” is hilarious. BTC’s cap is ~$1.6T today. Anthropic is reportedly flirting with $800–900B. Polymarket’s pricing the odds at ~43% which would mean Anthropic keeps ripping, and/ or BTC will...
Open‑source AI Still Censors when Inference Is Centralized
DeepSeek literally just blocked Jason’s response on a sensitive topic in real time… It started answering then the response just vanished. This is why “open source” does not mean free speech when the inference stack is controlled.
Human Drivers Add Security and Concierge Services in Autonomous Era
Actually, for Uber Black, Blacklane and private drivers this is standard (I use all three, all the time). For UberX? Sure, they would need to be convinced. in a world moving to autonomy, the opportunity for humans is to add security,...
Politicians Enable Fentanyl Crisis; Demand Zero Tolerance
San Francisco politicians and their constituents enable this suffering. They are the cause of it, because they can stop it instantly. Today, tomorrow and every one of the last 1,000 days this has happened. Fentanyl is a super drug and...
Slow, Safe Self‑Driving Rollout Essential to Prevent Tragedy
The roll out of self driving cars needs to be extremely thoughtful, slow and vigilant if we have a toddler struck like in this video from China, the whole industry will be put on ice. (This appears to be very real...
Earn While Learning VC: No Tuition, No Degree Required
$0 tuition Get paid to learn venture capital and startup creation at my firm in Austin We are hiring six “associates in training” You’ll start as a researcher and learn fund management, back office functions and the “qualified sorting” of...
Top Broadcaster @WorldWideWob Still Missing From Major Networks
How is @WorldWideWob not on Prime, Peacock or ESPN?! One the great broadcasters of our time — a pure talent. You could build a network around him. https://t.co/CcZtF6AUFs
‘86’ Isn’t a Call for Murder, Just Slang
Oh lordy... here comes the lawfare madness again 🤦 86 when I grew up in the restaurant business meant “to get rid of” something (ie “86 clams” meant to take clams off the menu). I was told it had two origins: 1....
Assessing $25
If this passes, what impact (if any) do you think @RoKhanna’s $25 minimum wage will have on unemployment rate in California? Show your work. https://t.co/kMug9xSbSQ
Five Key Areas for a Balanced, Fulfilling Life
There are five things you can focus on in your life that will help you lead a balanced and fulfilling life. https://t.co/BWmNyPrCL2
Balance Your Day with Sleep, Food, Exercise, Mindfulness, Connection
My “Big 5” for staying sane + sharp: Sleep Nutrition Working out Meditation Socialization Try to hit all 5 in a day, even if it’s just a small thing, don’t let it drop off. When one slips, everything else starts...
China's Golden Share Halts Meta's Manus Deal
China is blocking Meta’s Manus acquisition, and it might just be our news story of the year. If a startup is strategically important, the CCP can just reach through with a “golden share” (a “symbolic” 1% / board seat /...
Founder Loans Are Standard, NYT Misframes Controversy
I’ve invested in 700 private companies Providing liquidity and loans to high performing founders is completely standard. In fact, investors encourage loans and secondary sales for founders to enable them to go for the Gold — which is exactly what...
NYTimes Fuels Class Warfare with Micro‑looting Narrative
The NYTimes focus last week was micro-looting, social murder and meaningless private company transactions designed to ferment class warfare. Disgraziad
From YC Rejection to Military Contracts: Firehawk’s Rise
5 years ago, “defense startup” was a dirty word. Will Edwards says YC kicked them out of the interview when they heard what Firehawk was building. Today, Firehawk has several giant customers within key military agencies, PRINTING rocket propellant and...
Turn a Layoff Into Startup Success and Happiness
If you’re laid off, create or join a startup — that’s the best path to unlimited upside and happiness https://t.co/VbsStEV0EN
Request to Verify Source Behind White Supremacy Spike
.@grok find the original source of this data and fact check it What story was the cause of the spike in “white supremacy” @WSJ @NYTimesPR @washingtonpost @latimes please vet this and check in https://t.co/jiWxeWQ6BB
BitTensor's Incentive Structure Fuels Constant Exploitation
This is BitTensor’s biggest weakness 👇 Users (miners/validators) are incentivized to compete. This means gaming the system, exploiting every possible advantage. Subnets need to be built assuming people are gonna cut corners. Builders have to assume exploitation is the default....
BitTensor’s “Decentralization” Limited to 128 Subnets
If you’ve bought into the BitTensor hype train, you may be surprised to know it’s not quite as decentralized as you think. In fact, there are only 128 subnets on the system, that means only 128 projects can utilize its...
POTUS Pushes Zero‑tolerance on Fentanyl, Lenient Cannabis Reclassification
Reclassification is critical so that we can have a no-tolerance rule for fentanyl and meth, which are deadly, and a reasonable policy on plant medicine and cannabis — which experts believe are far less harmful (and in therapeutic or hospice...
Limited 100 Spots: Join Exclusive Deal Access
We are accepting 100 new members to https://t.co/6leeScCHo6 in Q2 I’ve been lucky enough to invest in great companies like @zipline @uber @RobinhoodApp and @calm over the years… and now I’m sharing access on a deal by deal basis with...
Double Standards: NYT Content Free, Wordle Blocked?
OK… so it’s ok for everyone to republish the nyt and for us to vibecode a free wordle competitor? , @NYTimesPR?
Seeking Objective Legal Vetting of Controversial Lawsuit
.@grok @AskPerplexity please vet this lawsuit and handicap the chances it’s a valid case or lawfare Be objective and truthful above all else Cite your sources
AI Surveillance Prunes Fraud, Elevates True Perform
Studying of teams with AI is the trend of 2026 1. Study your workforce with apis, key loggers and screen recording 2. Find out who isn’t working (fraudsters) and fire them 3. Find out who is simply taking credit for...
Own Your Intelligence with Custom Small Language Models
Your company shouldn’t be using LLMs. It should be using a proprietary small language model purpose-built for your organization. “Own your intelligence,” says Josh Sirota , founder of Eragon AI. Find out why this approach delivers a cheaper, better experience....
Founder Matters More than the Startup Idea
The best early-stage startup investment isn't actually the startup. It's the founder. When Joshua Sirota came through the Launch accelerator after getting rejected by YC, and my team, "I don't know if this startup works. But I know Josh is...
Factory Humanoids Ready Now; Home Robots Five Years Out
Home-based robots are about 5 years away from mass adoption ... but factory-based humanoids are ready for serious work today. Inside Factories (today; $10 an hour) --> Last-Mile Delivery (3 years; $5 an hour) --> Inside Home (5 years; $1...
Announcing “Lookmaxxxing at 50” Startup on All In
On the next episode of All In, @chamath and I will reveal our new startup... "lookmaxxxing at 50" in partnership with @Clavicular0 https://t.co/3KFw5I88pZ
Own Your Intelligence: Embed Data Directly Into Model Weights
The future of AI is about owning your intelligence. When your data is in the weights of an AI model, responses are cheap instant. A frontier model being used by your company shouldn’t have to look up basic facts, it...
Drones Replace Vans for Sparse‑Population Delivery
Did you know 99% of the US has fewer than 500 people per square mile, yet we're still delivering to all of it with a van… A Roman technology. Here’s how Etienne Louvet, CEO of Iona, is fixing this with...
Apple's Cash Soars, Product Innovation Stalls
Apple is an amazing company, that's printed money for a decade... .... but it's been uninspiring on the product front... excited to see if a product-focused CEO will make some bolder bets than the watch and airpods
More Startups, Fewer Staff, Jobs Demand Founder Mindset
1. We will have 10x the number of startups 2. .... with 50% less employees each 3. ... which means a LOT more jobs 4. ... but those jobs require a founder/startup mindset, which most folks simply don't have
Speculating Bitcoin Price without Saylor’s Massive Purchases
.@grok what would the price of $btc be if @saylor had not bought $61b+ / 34k+ bitcoin?
Iran's Swarm Boats Evade US Navy Despite Air Power
Someone educate me as to why the US Navy can't eliminate Iran's “mosquito fleet.” I get these are small, fast speedboats, but can't they be quickly eliminated by helicopters and jets, as well as ship-mounted guns? How many of these...
Recovering Iran's Nuclear Cache Proves Incredibly Complex
great overview of the quagmire of recovering Iran's nuclear material cache -- this wouldn't be a cake walk (so to speak) https://t.co/brALvwpspQ
Call to Examine Judge’s Lenient Record After Fatality
Rest in peace, Larissa Herold 🙏🏼 Austin reporters: perhaps we need to report on this judges last 100 cases and look for similar patterns of insane leniency leading to peaceful citizens being killed?
Join Icon: 3D‑Printed Housing, Infrastructure, Space Projects
If you’re a great builder and you want your work to matter, listen to Jason Ballard. Today, I gave a rare endorsement: Ballard is A+ character, and Icon is doing the kind of work tech should be doing. Dignified housing...
TAO Empowers Builders with Self‑Recruiting, Low‑Cost Compute
“TAO changed my life as a builder.” Seby, the founder of Resi Labs, on why BitTensor is gives builders an unfair advantage. Instead of begging for hiring, compute, and distribution, you plug into a network where incentives recruit the people,...