Spencer Nadolsky, DO
Obesity/lipid specialist physician; clear, evidence-based takes on nutrition, GLP-1s, supplements, and behavior change.
Calling It GLP‑3 Reveals Ignorance of Triple Agonists
If you use the terminology “GLP-3” instead of GLP-1/GIP/Glucagon receptor agonist or at least triple agonist, I’m going to assume you don’t know much about these medicines.
Lifestyle Changes Slash Disease Risk and Boost Longevity
- fewer heart attacks - less liver disease - less kidney disease - less obstructive sleep apnea - less knee pain in osteoarthritis - improved psoriasis - fewer alcoholic beverages consumed - potentially more years lived
GLP‑1 Restores Appetite Control, Overcoming Adverse Environments
The “root cause” is a dysregulated appetite with a terrible environment. The GLP-1 normalizes the dysregulated appetite and allows for navigation of the environment.

Preventing Obesity Beats Losing Weight—Lifestyle Alone Rarely Works
People didn’t lose weight in 1900. They were just thinner. Obesity was prevented. Losing weight isn’t the same thing as preventing it. Losing weight with lifestyle alone unfortunately isn’t effective for the majority of people.