Drug Hunter

Module 2, Section 2: The Druggable Interactome

The Module 2, Section 2 lecture introduces the druggable interactome, compiling key resources that map the human druggable genome, protein expression, kinase families, transcription‑factor proteomics, GPCRs, and ion‑channel complexes. It highlights quantitative estimates—over 3,000 proteins deemed druggable and hundreds of actionable kinases—while linking these datasets to disease relevance. The slide deck cites seminal literature that underpins current target‑identification strategies and points to emerging analytical methods for deeper interactome coverage. Together, these references form a roadmap for systematic target discovery across multiple protein families.