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Community-driven news and discussion focused on rapamycin and related longevity interventions.

[Cybersecurity Thread] ""Soon-to-Be-Released AI Models Could Enable a World-Shaking Cyberattack This Year", Protect Your Healthcare Data
News•Apr 7, 2026

[Cybersecurity Thread] ""Soon-to-Be-Released AI Models Could Enable a World-Shaking Cyberattack This Year", Protect Your Healthcare Data

Project Glasswing warns that emerging AI models could become vectors for massive cyber‑attacks, citing an 86% success rate for hidden prompt‑injection attacks and a 0.1% poisoned‑data threshold that corrupts agents with over 80% certainty. DeepMind identifies six attack layers—perception, reasoning, memory, action, coordination, and supervision—each already demonstrated in proof‑of‑concept form. OpenAI admits prompt injection may never be fully mitigated, even as firms rush to embed agents with email, banking, and code‑execution capabilities. The article urges immediate defensive steps for individuals and enterprises, especially those handling health data and forum platforms like Discourse.

By Rapamycin News
[Cybersecurity Thread] ""Soon-to-Be-Released AI Models Could Enable a World-Shaking Cyberattack This Year", Protect Your Healthcare Data
News•Apr 7, 2026

[Cybersecurity Thread] ""Soon-to-Be-Released AI Models Could Enable a World-Shaking Cyberattack This Year", Protect Your Healthcare Data

Project Glasswing warns that emerging AI agents are vulnerable to hidden prompt injections and memory‑poisoning attacks, with success rates of 86% and over 80% respectively. The research, cited by DeepMind, shows attackers can embed malicious instructions in HTML or contaminated...

By Rapamycin News
Growth Hormone Supplementation Can Restore the Thymus, but What Is Its Effect on Lifespan?
News•Apr 7, 2026

Growth Hormone Supplementation Can Restore the Thymus, but What Is Its Effect on Lifespan?

Recent debates on growth hormone (GH) supplementation highlight its ability to rejuvenate the thymus but raise serious concerns about lifespan effects. Experts from the 2013 Erice workshop and subsequent literature argue that while transient GH can restore immune tissue, chronic...

By Rapamycin News
Lest We "Off" Ourselves (Cautionary Examples)
News•Apr 7, 2026

Lest We "Off" Ourselves (Cautionary Examples)

Investigative videos reveal that wellness influencers Mark Hyman and Jordan Peterson suffered severe sepsis after receiving experimental stem‑cell and regenerative‑medicine injections from Dr. Adil Khan’s unregulated clinics. The series links spinal injections and intravenous therapies to life‑threatening infections, highlighting the...

By Rapamycin News
Parkinson's Disease
News•Apr 7, 2026

Parkinson's Disease

Recent preclinical and early clinical studies explore a range of nutraceuticals and repurposed drugs that target oxidative stress, metal homeostasis, and gut integrity in Parkinson’s disease. Benfotiamine combined with methylcobalamin showed symptomatic improvement in a case series and activates Nrf2...

By Rapamycin News
Vitamin C Re-Evaluated: A Direct Inhibitor of the 'Ferro-Aging' Clock
News•Apr 7, 2026

Vitamin C Re-Evaluated: A Direct Inhibitor of the 'Ferro-Aging' Clock

A 2026 Cell Metabolism study gave aged cynomolgus monkeys 30 mg kg⁻¹ vitamin C daily via drinking water for 40 months, showing direct inhibition of the ACSL4‑driven ferro‑aging clock. Pharmacokinetic data reveal vitamin C’s plasma half‑life ranges from 30 minutes to two hours at high doses,...

By Rapamycin News
New Study Says I Was Wrong About NMN and NR?
News•Apr 7, 2026

New Study Says I Was Wrong About NMN and NR?

Recent human trials show that nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN) raise blood NAD levels similarly, contradicting a small crossover study that claimed NR was superior. Both compounds appear to be metabolized largely by gut microbes into nicotinic acid...

By Rapamycin News
New Study Says I Was Wrong About NMN and NR?
News•Apr 7, 2026

New Study Says I Was Wrong About NMN and NR?

The debate between nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN) is losing relevance after recent trials. A crossover study of six adults showed NR raised blood NAD 2.3‑fold more than NMN, but a larger 65‑participant Nature Metabolism trial found both...

By Rapamycin News
Lactoferrin: A Milk-Derived "Immunoceutical" Reverses the Clock on Inflammaging
News•Apr 7, 2026

Lactoferrin: A Milk-Derived "Immunoceutical" Reverses the Clock on Inflammaging

Recent research highlights lactoferrin’s ability to modulate iron metabolism and reduce age‑related inflammation. A 2026 piglet study showed combined human milk oligosaccharides and lactoferrin enhanced lipid mobilization, antioxidant capacity, and neurodevelopment. A randomized trial in obese children reported three‑month lactoferrin...

By Rapamycin News
AGI/ASI Timelines Thread (AGI/ASI May Solve Longevity if It Doesn't "Kill Us All" First)
News•Apr 7, 2026

AGI/ASI Timelines Thread (AGI/ASI May Solve Longevity if It Doesn't "Kill Us All" First)

OpenAI has dismantled several core safety groups, including the superalignment and AGI‑readiness teams, prompting resignations from senior researchers. The company’s latest Future of Life Institute report card awarded it an F for existential safety, matching most rivals except Anthropic and...

By Rapamycin News
Lactoferrin: A Milk-Derived "Immunoceutical" Reverses the Clock on Inflammaging
News•Apr 7, 2026

Lactoferrin: A Milk-Derived "Immunoceutical" Reverses the Clock on Inflammaging

Recent peer‑reviewed studies reveal that lactoferrin, especially when paired with human milk oligosaccharides, enhances lipid mobilization, antioxidant capacity and neurodevelopment in animal models, while a 2026 randomized trial shows it improves weight, liver enzymes and insulin resistance in obese children....

By Rapamycin News
Lest We "Off" Ourselves (Cautionary Examples)
News•Apr 7, 2026

Lest We "Off" Ourselves (Cautionary Examples)

Investigative videos reveal that wellness influencers Mark Hyman and Jordan Peterson suffered severe sepsis after undergoing experimental stem‑cell and regenerative‑medicine procedures at Dr. Adil Khan’s unregulated clinics. The series links spinal injections and intravenous therapies to bacterial infections, highlighting the...

By Rapamycin News
University of Arizona Launches $12 Million Rapamycin Clinical Trial
News•Apr 7, 2026

University of Arizona Launches $12 Million Rapamycin Clinical Trial

The University of Arizona’s R. Ken Coit College of Pharmacy is launching a double‑blind, randomized Phase 3 clinical trial to test low‑dose rapamycin’s ability to boost resilience and immune function in adults aged 65 and older. The six‑year study, funded by a $12 million...

By Rapamycin News
University of Arizona Launches $12 Million Rapamycin Clinical Trial
News•Apr 7, 2026

University of Arizona Launches $12 Million Rapamycin Clinical Trial

University of Arizona’s R. Ken Coit College of Pharmacy is launching a double‑blind, randomized Phase 3 clinical trial to test low‑dose rapamycin’s ability to improve resilience and immune function in adults 65 and older. The $12 million study is fully funded by...

By Rapamycin News
Dr. Kaeberlein's Optispan Podcast Series - Rapamycin and More
News•Apr 7, 2026

Dr. Kaeberlein's Optispan Podcast Series - Rapamycin and More

AI modeling compares 6 mg rapamycin taken with grapefruit juice versus berberine 1000 mg daily. Grapefruit juice irreversibly destroys intestinal CYP3A4 and P‑gp, boosting rapamycin AUC 3‑4× and Cmax 2.5‑3.5×, effectively tripling the dose for up to three days. Berberine provides reversible...

By Rapamycin News
New Study Says I Was Wrong About NMN and NR?
News•Apr 7, 2026

New Study Says I Was Wrong About NMN and NR?

A recent small crossover study suggested nicotinamide riboside (NR) raised blood NAD 2.3‑fold more than nicotinamide mononucleotide (NMN), but a larger Nature Metabolism trial with 65 participants found both precursors increased NAD similarly. Mechanistic work shows oral NR and NMN...

By Rapamycin News
New Study Says I Was Wrong About NMN and NR?
News•Apr 7, 2026

New Study Says I Was Wrong About NMN and NR?

Recent human trials have shown that nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN) raise circulating NAD levels to a similar extent, contradicting a small Bergen study that suggested NR was superior. Both compounds appear to be metabolized largely by gut...

By Rapamycin News
New Study Says I Was Wrong About NMN and NR?
News•Apr 7, 2026

New Study Says I Was Wrong About NMN and NR?

Recent human trials have reignited the NR‑vs‑NMN debate, with a small six‑person crossover study suggesting NR raises blood NAD 2.3‑fold more than NMN, while a larger 65‑participant Nature Metabolism trial found no meaningful difference between the two. Both studies, however,...

By Rapamycin News
Canagliflozin - Another Top Longevity Drug
News•Apr 7, 2026

Canagliflozin - Another Top Longevity Drug

Canagliflozin and other SGLT‑2 inhibitors are gaining attention as potential longevity agents due to their ability to cut cardiovascular events, renal decline, and COPD exacerbations in patients with type‑2 diabetes. Recent meta‑analyses show reduced emergency‑room visits and lower mortality among...

By Rapamycin News
Life Expectancy in the USA and Around the World
News•Apr 7, 2026

Life Expectancy in the USA and Around the World

The article highlights a surge in avoidable mortality as Europe ages, linking air pollution to cardiovascular risk and noting a sharp decline in the United Kingdom's healthy life expectancy to 61 years. In the United States, liberal states have achieved...

By Rapamycin News

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