New Longevity Rx Platform Offers Proven Anti‑Aging Meds
I just launched a longevity Rx platform. Prescriptions I personally use are there. v1 is live now. Includes access to: + Tadalafil (Cialis) + Metformin + Oral Minoxidil + Tretinoin + Estradiol + Acarbose We’re working with licensed doctors and pharmacies to make these medications accessible. Lots more in v2 coming next week.
Breakthrough Therapies Extend Survival, Renew Hope for Terminal Illnesses
For those of you who have a terminal illness, a chronic condition, or debilitating health issue, there is new reason to have hope. New treatments are arriving that buy more time for the next to arrive. Even for the most...
Jet Lag Adds Years to Biological Age, Study Shows
Jet lag increased my biological age by ~13 years. > as measured by grip strength > pre-travel: 141 lbs, grip age 48, ~98th percentile > post-travel: 125 lbs, grip age 61, ~98th percentile Traveled across 7 time zones, Los Angeles to Australia. Grip strength...
You're Exercising Wrong
The video challenges the “one‑size‑fits‑all” fitness myth, arguing that most people exercise incorrectly and jeopardize longevity. It proposes a holistic framework of five “pillars”—strength, low‑intensity cardio, high‑intensity cardio, mobility/flexibility, and balance—to maximize lifespan and functional health. Evidence is presented that muscle...
Meet Kate Tolo: First Ultra‑Measured Woman for Free Health Data
We now have a female Bryan Johnson. It’s Kate Tolo. She will become the most measured female in history. +$2 million of spend per year + Developing a female-specific protocol + Sharing everything for free To start, she will spend 3 months mapping her baseline....
Brain Holds 3,000× More Microplastics Than Blood
This new perspective study reports that our brains are carrying 3,000x more microplastic than our blood. Microplastic burden of the human brain rose ~50% between 2016 and 2024. The average brain now carries roughly: > 11x the load of the liver > 11x...
Sleep First: The Ultimate Longevity Hack
This is it. Everything learned spending millions on longevity. From: Your Immortal Unc and Auntie. To: Our Immortal nieces and nephews. 0. Sleep is the world's most...
Nature’s Quiet Reveals What Modern Life Obscures
Kate and I spent the weekend forest bathing. A cabin in deep woods, a river feeding the ocean, tides marking the day. We hiked, watched, listened, and smelled. We let the quiet settle. By Sunday morning, my resting heart rate dropped...
Body Like when Sleep
The video delivers concise sleep‑hygiene guidelines, emphasizing physiological cues and environmental controls to improve rest quality. It stresses keeping heart rate low by avoiding heavy meals within four hours of bedtime, eliminating screens an hour before sleep, and engaging in calming...
Phone‑Free Forest Bathing Cuts Resting Heart Rate
48 hrs forest bathing this weekend. No phone. Resting heart rate lowered 10%. It was glorious. Have you done that recently?
Peptides Boost Hormones, Yet Trigger Serious Metabolic Side Effects
People mistakenly believe peptides are only good. Peptides can be bad, too. They can cause adverse effects. Some dangerous. I did a peptide experiment and measured its effects in my body. The results are complicated. I tried a peptide called CJC-1295....
CJC‑1295 Extends Sauna Heat‑Shock Time, Delays Threshold
Bodybuilders use the peptide CJC-1295 to grow muscle. I tried it for two weeks. Unexpectedly, it changed how my body responded to 200°F sauna protocol. First, the good. I spent more total time above the heat shock protein (HSPs) threshold. This...
New Peptide Experiment, Results Coming Soon
The video announces a self‑experiment that stacks two synthetic peptides—Turppatide and CJC-1295 DAC—to see whether their opposing side‑effects neutralize each other while preserving their anabolic benefits. Turppatide is marketed for metabolic optimization but can elevate heart rate and disrupt sleep. CJC-1295...
5-MeO-DMT Boosts Brain Complexity, Rekindles Childlike Curiosity
My brain became 40% more child-like in 3 minutes. This is what it felt like. Me: “What question do we ask them next?” My daughter: “Are they scared of the dark too?” My six year old daughter and I were...
Today's Daily Progress Equals Decades of Past Growth
Progress achieved in 1 day in May 2026 is equal to: > 19 days in 2000 > 1.6 years in 1900 Derived from a geometric mean across 8 metrics: compute per dollar, DNA sequencing throughput per dollar, frontier AI training scale, papers published...