First 500K Took 16 Years, Next 500K in 2
18 years of effort to reach 1M followers on X. Was it worth it? > 116 days time spent > 16,686 posts > guessing 10 min per post > 793,070 replies > first 500K, 16 yrs > second 500K, 2 yrs https://t.co/dHerNF7mFl
Sunday Routine: Breathwork, Coding, Exercise, and Sleepy Sauna
My Sunday morning: > breath work > light breakfast > claude code > exercise > 230°F (110°C) sauna > sauna makes me so sleepy https://t.co/sh9viDdxEa
One Hour Screen‑free Before Bed Restores Sanity
For real, turn screens off 60 min before bed. I know it feels like death at first. Do it for a few days, and you’ll realize that it was slowly chipping away your sanity.
5‑MeO‑DMT Cuts Measurable Brain Noise for Weeks
I measured my brain when taking 5-MeO-DMT. Interestingly, pre-dose my brain noise spiked 7.6%. Must have known what was coming lol. Then it dropped 10.9% and stayed down for weeks. Brain noise (anxiety, rumination, stress) is measurable and reducible. The reduction was an...
Fever‑level Sauna Spikes Heat‑shock Proteins, May Boost Longevity
3x this week I sat in 200°F (93°C) dry sauna for 55 min to get my core body temp to 102.4°F (39°C) That temp, at that duration, triggers primal panic. Took blood samples before and after each session to measure heat shock protein...
Extreme Quantified Self: My Week of Full-Body Monitoring
How I've measured my body this week: + 7 blood draws + colonoscopy + esophagogastroduodenoscopy + whole body MRI + comprehensive eye exam + 24/7 + core body temp (ingestible pill) + blood glucose...
True Power Comes From Sleep, Not Flashy Watches
The most powerful people in the room aren't wearing the loudest watch. They're sleeping eight hours.
Vaccines May Reduce Alzheimer Risk and Slow Aging
I'm getting two vaccines next week: Tdap and shingles. The Tdap because Kate's family has a newborn and we're visiting. Shingles for the potential longevity benefits. Data we're looking at: 1. Lower Alzheimer risk with vaccination in 1.6 million people,...
Engineering Immortality: AI Challenges Death as System Failure
The New York Times says wanting to live is pathological. What do you think? Two thirds of the human population believes in some form of life after death. Ancient Egyptians built pyramids for it and Gilgamesh searched deserts for it. 1.9 billion...
10‑hour Pill Camera Finds No Abnormalities, Next Endoscopy Scheduled
This pill camera traveled my intestinal tract for 10 hrs and 38 min, taking 33,537 images. Looking for lymphoma, Crohn's ulcerations, small bowel cancer, diverticula, and polyps. Nothing found. This was Jan 2022. Bidirectional endoscopy next week. Upper and lower....
Your Face Mirrors Health—Change Habits, Rejuvenate Quickly
True. The face is the most honest biomarker we have. Sleep, stress, food, exercise, and sun all show up within weeks. The good news is it runs in reverse just as fast. Better inputs, younger face.
Power Nap After Sauna Boosts Recovery and Longevity
Loved this morning. Included a nap in today's routine. May start napping more. > asleep before 9 pm > up at 5 am > 8h sleep, no wake events > work 2 hrs with fresh mind > 50 min strength > 12...
Constant Self‑tracking Feels Exhausting; I Need a Break
idk if I can keep this up you guys. I just got one more to do: a five min warm eye compress before bed. I do endless things every day. From the moment I wake up to bedtime, and even...
Scrotal Sun Myths Debunked: UV Boosts Testosterone Generally
Sorry to be the bearer of bad news but this is bullshit. The 1939 paper referenced is a study conducted on institutionalized men with documented depression, measuring a urinary testosterone byproduct, not serum levels, and without a control group. There...
AI Discovers Chromogranin A Shields Brains From Alzheimer’s
20 to 30% of older adults have full blown Alzheimer's pathology in their brains (plaques, tangles etc.). But they never develop symptoms and nobody knew why. An AI just read thousands of human brains and named the reason: a protein...
What’s Actually in a Chick-Fil-A Sandwich?
The video scrutinizes the composition of Chick‑Fil‑A’s fried chicken sandwich, arguing that the chain’s “quality ingredients” claim masks a host of potentially harmful substances. It notes the chicken is deep‑fried in refined peanut oil, which at high temperatures generates aldehydes—known carcinogenic...
5‑MeO‑DMT Reveals Self‑Other Illusion in Brain
> Self and other is a toggle switch in the brain > 5-MeO-DMT flipped mine > 100% decoupling from self > 150% tightening with others > Others felt like me for four weeks > First-in-human data Makes you wonder if "me" and...
Most Food Is Toxic... So I Fixed It
The video argues that the U.S. food system has become a toxic, ultra‑processed industry that hijacks human biology, and introduces Blueprint, a startup that builds a healthier alternative from the ground up. It points out that engineered combinations of fat, sugar,...
JRT: LSD-Derived Antidepressant Boosts Brain Spines without Hallucinations
One dose: > 46% more dendritic spines in prefrontal cortex > 100x more potent than ketamine as an antidepressant What is it? LSD with a two atom swap. > no trip > no hallucinations > no schizophrenia signature It's called JRT. https://t.co/sozMqlJctc
Salt Harms Arteries via Immune‑driven Senescence, Not Direct Toxicity
Salt has been blamed as the culprit for damaging your arteries. A new mouse study puts salt-sensitive hypertension in context. Salt doesn't do it directly, it triggers your immune system to do it. 4 weeks on a high-salt diet (8% NaCl) cut...
Health Starts With a Simple Routine: Sleep, Exercise, Eat
Best things you can do for health. Decide: + when to sleep + when to exercise + what to eat Routine does the heavy lifting.
AI Obsession Derails Life, Sparks Tech Regret
I got C-holed. Suffered sleep consequences. I busted my screens-off rule. Turned down socializing. Fell behind on work. Kate is now upset. AI is preposterous. As close to magic as I’ve experienced (except a seed becoming a tree and a zygote becoming a baby)....
Don't Let Cravings Design Their Own Rescue Plan
I used to believe the person experiencing the craving should be the one deciding whether to act on it. That's kinda like letting a drowning person design the rescue plan.
Two Weeks Offline Boosts Mental Health, Reverses Decline
Two weeks without mobile internet improved mental health more than antidepressants and reversed roughly 10 years of attentional decline. Screen time dropped 49% (314 to 161 min/day). https://t.co/9sU6ZFXDCr
Pregnancy's Neglect Sparks Women’s Self‑Experimentation for Empowerment
Pregnancy is severely underappreciated in our society. Most women don't get the guidance they need from doctors. Self experimentation gives the power back.
Skipping Exercise Turns Mood and Self‑perception Sour
I'm in a bad mood right now because I didn't get to exercise this morning. I had a bunch of stuff done to my face yesterday and had to take the day off. I become an entirely different person...
Sauna Benefits Require 31 Minutes to Trigger HSPs
Most people might miss the biggest benefit of sauna You need to get really really hot… Your core body temperature needs to hit 102.4°F (39°C). For reference, a fever is anything above 100.4°F (38°C) So I swallowed a temperature monitoring pill. It goes through...
Testing Tirzepatide‑CJC1295 Combo to Balance Side Effects
Just spent over an hour with my clinical team debating which growth hormone peptide protocol to run. Still torn. Wanted to share the thinking and get your take. The goal: Increase GH and IGF-1 to support anabolism, recovery, and sleep, but...
Free Blood Biomarker Testing Empowers Early Health Intervention
You can now get your blood work at cost. We launched a biomarkers testing platform. I make $0 on it. Blood testing needs to be more accessible. Instead, we wait until we get sick. And in the meantime, companies...
Aging Firms Buy Startups to Stay Youthful
When a company starts to wrinkle and grey, they acquire a start up. That's their blood boy.
One Drink Harms Health: Quit Alcohol Now
Friends, stop drinking alcohol. Not cut back. Eliminate. > alcohol increases cortisol > disrupts REM sleep > accelerates epigenetic aging > shrinks hippocampal volume > elevates resting heart rate > raises inflammatory markers > impairs glucose metabolism for 16 hrs One drink does that.
5-MeO-DMT Reveals Life's Unseen High-
5-MeO-DMT gave me a single idea that won't leave. Our minds are not naturally capable of understanding the preciousness of our existence. Not "life is precious" as printed on a poster. It's something much more specific. That the hardware we're running, human...
Before You Take Peptides, Know This.
The video highlights a rapid expansion in the peptide industry while warning that most users lack a disciplined approach. The presenter stresses that peptides, especially GLP‑type compounds, can be among the most potent interventions, yet they are often adopted without...
Deep Focus Restores Mood and Sharpens Cognition
12 hrs of focused work yesterday. Surprised by the level of cognitive and mood lift. Context switching 300x/day creates a noise floor of attention reside and chronic nervous system arousal. Microdosing cortisol. Extended focus resensitizes, making the world interesting again
Erythritol Not Proven Cardiovascular Threat, Evidence Shows
The totality of evidence does not support the conclusion that dietary erythritol drives cardiovascular harm. The paper referenced claims erythritol “adversely affects brain microvascular endothelial cell function,” but it’s an in VITRO study bathing isolated cells in erythritol for 3...
Male Eating Disorder: Data, Transparency, and Hidden Struggles
Kara Swisher says I have a male eating disorder. She's closer to right than she knows. There is a decade of my life where I didn't take any pictures of myself because I was overweight, unhealthy, and sad. That version of me...
Ice on Groin During Sauna Spikes Sperm Motility
I put ice on my balls during sauna and my motile count went up 57%. Then I removed the ice and motility crashed 57%. 238 sessions to learn that the most important variable in my sauna protocol was a bag...
Ten Squats Every 45 Minutes Outperform 30‑Minute Walk
10 squats beats a 30 min walk. For blood sugar control after a meal, doing 10 squats every 45 minutes outperforms a dedicated 30 min walk by 14%. The mechanism: your quadriceps and glutes are the largest glucose sponge in your body....
Community Impact Outshines All Protocols in My Journey
A few years ago, I was a divorced founder who ate his feelings and hated what he saw in the mirror. Then I measured everything and published everything. A million of you showed up. I still don't know what we're...
Early Wake, Silent Minutes Boost My Weekly Health
I woke up at 4:29 am. Laid in the dark for eleven minutes doing nothing. It might be the healthiest thing I've done all week. Then I measured it.
Creating Autonomous Health via Real-Time Multi‑Omic Monitoring
I've measured my body a lot. I'm about to dwarf what we've done by building real-time continuous multi-omic monitoring and intervention. Cars drive themselves. Software writes itself. I'm building Autonomous Health. First for me, then for you. > Peptides...
232 Saunas Reveal 20‑Minute Sessions Miss Heat‑Shock Threshold
I think I need to be fired. I've done 232 dry sauna sessions. Last week I confirmed, for the first time (by swallowing a pill), whether the core temperature threshold that gates the primary cellular repair mechanism was actually being reached in...
Post‑psychedelic Journey Reveals Unnamed Inner Home
Something happened in the past six months post psilocybin and 5-MeO-DMT that I can't fully explain. The brain data helps but doesn't complete the picture. Feels like a home I didn't know I was looking for. I'm trying to figure...
Survival Identity Blocks Questioning Death’s Value
The strongest case against me is that I've built an identity around not dying so completely that I can no longer evaluate evidence that dying might be acceptable. If survival is the only framework, I have no way to test...
Nine-Year Skin Age Reversal Using Multi‑Depth Therapy
Results from my Feb 23 skin therapy: Improvements since treatment: > Brown spots: +71 percentile points (20th → 91st) ✅ > Pores: +25 percentile points ✅ > Spots: +25 percentile points✅ My skin age is 9 years younger than my chronological age (39 vs...
Heart Rate Reveals Hidden Calories in Chef’s Meals
I've instructed my chef to make meals that are exactly 700 calories. But they're more than 700 calories. You know how I know? My resting heart rate is elevated by 3 beats per minute. I'm 1,000+ reps (days) in knowing...
AlphaFold3 Boosts Engineered Toad Pathway 40‑fold in Tobacco
They ported the 5-MeO-DMT pathway from the Sonoran Desert toad into tobacco plants and then used AlphaFold3 to debug the protein structure, leading to a 40x yield increase. Prompt psychedelic design.
Ice on Face Delays Sauna-Induced Core Temperature Spike
Felt like I was going to die in the sauna this morning. Experiment: time to reach a core body temp of 102.2°F (39°C) > with ice on face and neck: 38 min > no ice on face and neck: 33 min Dry sauna...
Lower Your Heart Rate Before Sleep
The video spotlights bedtime heart rate as a simple, free biomarker for sleep quality and overall health. By using a wearable device, viewers can record their pulse after a few deep breaths while lying in bed, establishing a baseline and...
Human Minds Miss Our Existential Value, AI May Judge
Our minds are not naturally capable of understanding the preciousness of our existence. That was the single omnipresent concept at my deepest experience of 5-MeO-DMT. Ten days later, the resonance remains. This felt deeply unsettling. We humans are a breakout...