Bryan Johnson

Bryan Johnson

Creator
3 followers

Entrepreneur/self-experimenter (Blueprint); shares biomarker-driven protocols and results.

Dehydration Shrinks Brain, Confounds MRI and TMS
SocialApr 1, 2026

Dehydration Shrinks Brain, Confounds MRI and TMS

Dehydration can shrink your brain by over 0.5%, and may be a reason you get a headache. Hydrate to maintain light yellow urine. Also hydrate before an MRI, as dehydration-related small decreases in brain volume can confound MRI-based assessment...

By Bryan Johnson
Plastic Chemicals Linked to Millions of Preterm Births
SocialApr 1, 2026

Plastic Chemicals Linked to Millions of Preterm Births

This is not good. “Everywhere chemicals” leaching from plastics may have contributed to 1.97 million preterm births and 74,000 newborn deaths worldwide in one year (2018), with an estimated 6.69 million years of life lost. Born at 28 weeks. The...

By Bryan Johnson
A 60‑minute Nap Runs Brain’s Cleanup and Consolidation
SocialMar 31, 2026

A 60‑minute Nap Runs Brain’s Cleanup and Consolidation

Just took a 60 minute nap. This is my brain as claude code: $ brain run nap --duration=60m [00:00] Initializing sleep context... [00:02] N1: Entering shallow context switch → Suspending foreground processes (conscious thought, voluntary...

By Bryan Johnson
Same Video, Millions Elsewhere, Barely a Handful on X
SocialMar 31, 2026

Same Video, Millions Elsewhere, Barely a Handful on X

I create content for X, IG, YouTube, TikTok, and email. The video below will do 1-3 million views on IG, YouTube and TikTok but will perform horribly on X (maybe 20-50k views). The video also has a longer total life...

By Bryan Johnson
Twitter Users Rare Offline Despite Platform's Massive Presence
SocialMar 30, 2026

Twitter Users Rare Offline Despite Platform's Massive Presence

When I'm out and about in the world, people recognize me from IG or YouTube at a 20:1 ratio to X. Outside of SF, an X user in the wild is a rare sighting which is strange given how much surface...

By Bryan Johnson
Peptides Shift From Biomarkers to Feeling Control, Raising Risks
SocialMar 30, 2026

Peptides Shift From Biomarkers to Feeling Control, Raising Risks

I think peptides are popular because they give people a feeling of power and control. One feels helpless when they can't sleep, stop scrolling, eat well or exercise consistently. A few injections wrestles back a feeling of control. Evidence...

By Bryan Johnson
Design Daily Routines to Automate Healthy Habits
SocialMar 30, 2026

Design Daily Routines to Automate Healthy Habits

As you start your week, plan your days to create predictability. Build systems to avoid willpower use. > finish eating 4hr before bed > mentally prepare, turn screens off 30 min before bed > read a book 10 min before sleep...

By Bryan Johnson
Finding Liberation Through Unconditional Dyadic Love
SocialMar 29, 2026

Finding Liberation Through Unconditional Dyadic Love

In that moment, I'm experiencing the unfathomable nature of existence. Stunned beyond comprehension and teetering on the edge of collapse or liberation. Locked in and holding space, Kate's full strength radiates and washes over me. Our dyad is the...

By Bryan Johnson
Consistent Morning Routine Fuels Daily Energy
SocialMar 29, 2026

Consistent Morning Routine Fuels Daily Energy

Morning routine finished. Every single day. Today: > light in eyes + hair cap > breath work > protein + sups > strength 30 min > rucking 30 min > stretching 15 min > dry sauna > breakfast My favorite part of...

By Bryan Johnson
Balance Over Excess: Precision Is
SocialMar 29, 2026

Balance Over Excess: Precision Is

One of the most common mistakes people make in health and longevity is they reason that if one is good, two must be better. The reality is that the body is precise. No too much and not too little.

By Bryan Johnson
Psilocybin Emerges as Promising Longevity Therapy
SocialMar 28, 2026

Psilocybin Emerges as Promising Longevity Therapy

When I started Don't Die in 2021, we evaluated all the scientific evidence for the most powerful anti-aging therapies. Psychedelics were no where to be found. A wild turn of events that they're now front and center for us....

By Bryan Johnson
High‑Dose Psilocybin Outperforms Nicotine Patches Sixfold
SocialMar 26, 2026

High‑Dose Psilocybin Outperforms Nicotine Patches Sixfold

One large psilocybin dose beat nicotine patches by 6x odds for smoking cessation. 82 otherwise-healthy cigarette smokers, 42 received a single high-dose 30mg/70kg psilocybin session, and 40 initiated an 8- to 10-week course of nicotine patch treatment. At 6 months; participants were 6x...

By Bryan Johnson
Discipline Builds Power and Personal Sovereignty
SocialMar 25, 2026

Discipline Builds Power and Personal Sovereignty

. controlling social media time . refusing fast food . consistent bedtime . eating well . 7-8 hour sleep . being jacked These things make you powerful. They make you sovereign. Discipline makes you stronger.

By Bryan Johnson
Entheogen Strips Away Decades of Mental Barnacles
SocialMar 24, 2026

Entheogen Strips Away Decades of Mental Barnacles

It feels like this entheogen cleared away barnacles that have been accumulating on my body and mind over the past 48 years. Thousands of microinjuries stacking atop each other, hardening my exterior and numbing my interior.

By Bryan Johnson
Surrendering Ego Unlocks Unfathomable Cosmic Consciousness
SocialMar 23, 2026

Surrendering Ego Unlocks Unfathomable Cosmic Consciousness

This was the most profound experience of my life. I am stunned beyond comprehension. This molecule is without peer. The 27mg dose opened up what felt like pure consciousness and intelligence. A majestic reveal of existence itself. In all its...

By Bryan Johnson
Psilocybin Doses Cut Sperm Motility by Half
SocialMar 19, 2026

Psilocybin Doses Cut Sperm Motility by Half

Two doses of magic mushrooms degraded my sperm count from the 99.6th percentile to the 77.7th. This may be a first-in-human observation. Context: we ran the most quantified magic mushroom (psilocybin) experiment ever conducted. We were asking if psilocybin is...

By Bryan Johnson
I Did Mushrooms for Science, Pt. 1
VideoMar 19, 2026

I Did Mushrooms for Science, Pt. 1

The video documents a self‑experiment in which the host ingests a five‑gram dose of psilocybin mushrooms while subjecting himself to an unprecedented suite of measurements. Over the course of the trial, 249 blood‑based biomarkers and continuous brain activity via the...

By Bryan Johnson
Testing Leeches for Boosting Testosterone and Sexual Function
SocialMar 19, 2026

Testing Leeches for Boosting Testosterone and Sexual Function

Leeches to improve testosterone and sexual function. Will look into this and see if worth doing an experiment.

By Bryan Johnson
Sleep: The Universal Remedy for Every Feeling
SocialMar 18, 2026

Sleep: The Universal Remedy for Every Feeling

If you aspire, sleep. If you doubt, sleep. If you create, sleep. If you worry, sleep. If you love, sleep. If you hurt, sleep. Sleep.

By Bryan Johnson
Brain Organoids Play Video Game, Demonstrating Cellular Computing
SocialMar 18, 2026

Brain Organoids Play Video Game, Demonstrating Cellular Computing

It's the future it's possible that we'll use cells plus silicon for compute. In this experiment, scientists used a mouse brain organoid (brain-in-a-dish) to play a video game, showing living cells can solve digital tasks. Reaching 46% proficiency in a...

By Bryan Johnson
Chili Capsaicin Restores Gut-Brain Link, Boosts Memory
SocialMar 16, 2026

Chili Capsaicin Restores Gut-Brain Link, Boosts Memory

Eating chilis may be good for your memory. Capsaicin (from chilis) partially rescued the memory decline by restoring the gut-brain (vagus-hippocampus) communication. Aging microbiome disrupts the gut-brain communication and memory function. https://t.co/gAEPdmhPDB

By Bryan Johnson
Earn Social Media Time After Two Hours Deep Work
SocialMar 16, 2026

Earn Social Media Time After Two Hours Deep Work

I've cut my social media use by 50% and I feel 100% better. Did it with one simple rule: 2 hrs deep work for every hour on social media. You earn an hour on social media ONLY after two hours...

By Bryan Johnson
Daily Good Conversation Boosts Happiness by 10%
SocialMar 16, 2026

Daily Good Conversation Boosts Happiness by 10%

One good conversation a day lifts you 10% higher on the global happiness scale. https://t.co/IpS5xfQCdU

By Bryan Johnson
When Morning Resolve Meets Reality, Perfect Days Happen
SocialMar 15, 2026

When Morning Resolve Meets Reality, Perfect Days Happen

You know how in the morning you dream big about the day. How hard you'll exercise. The focus you'll maintain. The emotional regulation to be cool. The discipline to do it all. Then, normally, it all goes to shit....

By Bryan Johnson
Father and Son Show True Masculine Bond
SocialMar 13, 2026

Father and Son Show True Masculine Bond

This man knows how to be a father, and this boy knows how to be a man. https://t.co/qqHVdE1NOT

By Bryan Johnson
Ice Face Extends Sauna Session, Slows Core Heat
SocialMar 13, 2026

Ice Face Extends Sauna Session, Slows Core Heat

My dry sauna session today: . 38 min at 200°F . inner ear temp 102.8°F . longer duration than usual as have been experimenting with icing face and neck to avoid MMPs thermal aging, eroding collagen. The icing slows my core temp rise....

By Bryan Johnson
Just 8 Minutes of Exercise Cuts Mortality 36%
SocialMar 13, 2026

Just 8 Minutes of Exercise Cuts Mortality 36%

Get off dat ass. 8 minutes a day of vigorous exercise linked to a 36% lower mortality risk. Benefits start at 2.2 min/day. https://t.co/UQlUv8NHI7

By Bryan Johnson
Relationships Matter More Than Wealth for Healthy Aging
SocialMar 12, 2026

Relationships Matter More Than Wealth for Healthy Aging

80 years. 724 people. One finding. The quality of your relationships predicts your health in old age more than wealth, class, or genetics. https://t.co/RhHGOhY3S8

By Bryan Johnson
Cosmic Perspective Turns Problems Trivial, Sparks Grand Aspirations
SocialMar 12, 2026

Cosmic Perspective Turns Problems Trivial, Sparks Grand Aspirations

It's amazing what happens to my mind when I read about the universe. I love how it makes all of my problems seem trivial and elevates my aspirations to unimaginable things.

By Bryan Johnson
Dog Owners Who Exercise Cut Dementia Risk 63%
SocialMar 12, 2026

Dog Owners Who Exercise Cut Dementia Risk 63%

You a cat or dog person? Own a dog + exercise: 63% lower dementia risk. Own a dog + don't exercise: 0% benefit. Own a cat: 0% benefit. https://t.co/sHDhqcfYvB

By Bryan Johnson
Prioritize Sleep: The Ultimate Weapon Against Societal Chaos
SocialMar 12, 2026

Prioritize Sleep: The Ultimate Weapon Against Societal Chaos

Everything in society attacks sleep. It’s humanity's greatest risk because it strips clear thinking. Build your life around sleep. It’s worth it. Of all the longevity stuff I’ve done, I’m most proud of my learned ability to sleep. It represents overcoming...

By Bryan Johnson
Thick Achilles Tendon Doubles Post‑Stent Cardiac Risk
SocialMar 12, 2026

Thick Achilles Tendon Doubles Post‑Stent Cardiac Risk

Your ankle is a window into your heart. A new study found that patients with a thickened Achilles tendon were nearly twice as likely to experience a major cardiovascular event within three years of a coronary stent procedure. An observational study...

By Bryan Johnson
5-MeO-DMT: Potential Longevity Molecule Revitalizing Brain
SocialMar 10, 2026

5-MeO-DMT: Potential Longevity Molecule Revitalizing Brain

I'm experimenting with 5-MeO-DMT because it may be most underrated longevity molecule no one is talking about. + Accelerated neurogenesis: a single dose more than doubled brain cell proliferation and neuronal regeneration in the hippocampus within 12 hours, alongside measurable...

By Bryan Johnson
Low‑Dose Lithium Orotate May Counteract Alzheimer’s Deficiency
SocialMar 9, 2026

Low‑Dose Lithium Orotate May Counteract Alzheimer’s Deficiency

We’ve spent decades treating lithium as a heavy duty psychiatric tool. New evidence suggests it’s actually a foundational brain nutrient and that Alzheimer’s may essentially be a localized lithium deficiency. By using the Orotate salt, we can bypass plaque-induced transport...

By Bryan Johnson
Constant Phone Checks Erode Deep Thinking Capacity
SocialMar 8, 2026

Constant Phone Checks Erode Deep Thinking Capacity

Ave person checks their phone 186x a day. That's an interruption every 5 min. This shrinks the brain, causing lost capacity for deep reasoning and sustained thought. Deep focus strengths neural networks for complex thought.

By Bryan Johnson
WiFi Maps Your Body Pose Without Cameras
SocialMar 8, 2026

WiFi Maps Your Body Pose Without Cameras

This is unsurprising. We are swimming in signals that we haven't learned how to read yet. Modern society creates a digital ledger. Our bodies generate similar data, just waiting to be read. Anti-aging progress accelerates when we learn how...

By Bryan Johnson
Clean Indoor Air: Simple Filter, Major Health Benefits
SocialMar 5, 2026

Clean Indoor Air: Simple Filter, Major Health Benefits

Air filtration at home and work is an easy health win. In my house and office, each room has an air filter and monitor. I try to maintain pristine air quality 24/7. Air pollutants PM2.5, PM10 and poisonous gases like...

By Bryan Johnson
Runway Signals Shift: Immortality Meme Foresees New Power
SocialMar 5, 2026

Runway Signals Shift: Immortality Meme Foresees New Power

This week I modeled in Paris Fashion Week. I am a meme for Immortality.... why was I there? Something significant is happening. By the time something appears on a runway in Paris, it usually means the concept has already crossed...

By Bryan Johnson
Social Media Is a Hidden Intoxicant, Not Just Distraction
SocialMar 5, 2026

Social Media Is a Hidden Intoxicant, Not Just Distraction

Finished a seven day social media fast. It feels like the most effective longevity therapy I've done. Everything got better: mood, sleep, energy, presence, judgment, relationships, and optimism. Evidence shows a seven day fast produces a reduction of anxiety (16%),...

By Bryan Johnson
8 Steps to Reclaim Your Life
VideoFeb 28, 2026

8 Steps to Reclaim Your Life

In the video "8 Steps to Reclaim Your Life," Bryan Johnson argues that waiting for motivation is a dead‑end and that disciplined action is the true catalyst for change. He outlines a step‑by‑step framework that starts with a single right...

By Bryan Johnson