Wearables Create Lifelong Health Baselines for Future Goals
Wearables aren’t just for tracking you in real time They’re building your personal baseline The numbers you see today become the targets you’ll aim to return to decades from now https://t.co/S44Yk812Gp
ER-100 Cleared for Trials; Safety Promising, Translation Uncertain
So far, the data suggest ER-100 should be safe in humans, and the FDA has cleared us to move into clinical trials. Translation from primates to humans is never guaranteed If it doesn’t work as hoped, we’ll learn & improve, just...
OSK Reprogramming Restores Adult Heart Regeneration
NEW STUDY: OSK rewinds the clock and pushes adult heart cells into a regenerative state that improves heart repair Why is this such a big deal? Because adult heart cells do not meaningfully divide, which is why the heart heals with scar...
Scientists Save Billions; CRISPR Cures Sickle Cell
You live in luxury. Without scientists, 6 billion of us would not be alive & the rest would live in hell. Remember that Great choices @brkthroughprize 🏆 Congrats to my colleague @Harvard, Stu Orkin, who won the prize for helping cure...
Top Scientist Warns US Dismantling Biomedical Infrastructure
Breakthrough Prize winner Dr. Stu Orkin: We were in a golden age of biomedical science. Universities were operating at high efficiency and speed. They’re disassembling [US] scientific infrastructure. I’m at a total loss to explain why people in leadership would...
Breakthroughs Now Cost Jeans, Not Billions
What once took $2B and an army of scientists was just done in a kitchen for the price of a pair of jeans Most people have no idea how fast science is moving
Future Medicine Targets Aging, Not Just Symptoms
The future of medicine is treating causes, not symptoms. Aging is the main cause of disease
Two Nutritious Meals a Day Suffice for Desk Workers
For people with a desk job, which is 80% of us, two nutritious meals a day usually provide all the calories we need. If you overdo it one day, the next day eat less
NAD+ Rhythms Drive Sleep, Aging; Resetting Delays Decline
NEW PAPER: Ups & downs in NAD+ over 24 h dictates our body's clock & sleep but declines with age. Disrupting the cycle promotes mouse aging & restoring it improves fitness & metabolic function, pointing to "circadian reprogramming" as a...
Stop People‑Pleasing: Upgrade Your Life, Family, Career
If you’re a people pleaser, outgrowing it will be the biggest upgrade you will make to your life, family and career Trust me on this 🚀
Partnering with Epigen
Dr. @M_S_Ringel is a knowledge fountain. COO of @lifebiosciences & a world's expert in epigenetic rejuvenation. Formerly Senior Partner @BCG for 20 years, it's a thrill to be working with him on the trials
Prof. Sinclair’s Aging Research Redefines My Perspective
I get the best emails: Dear Professor Sinclair, I came across your work on aging [and how it might] be modulated or restored. I was perfectly happy with my old way of thinking about aging until you showed up. Thanks for that. Hannah
Reversing Aging Could Halt Chronic Disease Progression
Aging is the primary driver of most chronic diseases. But what if aspects of aging can be reversed? I join @TomBilyeu on Impact Theory to discuss the latest about what we’re learning in the lab and in human clinical trials Full conversation:...
High‑Resolution TORC2 Structure Opens Path to Age‑Related Therapies
Activating TORC2 holds potential in medicine for treating age-related memory & hearing loss. New study out today @MolecularCell reveals the structure of TORC2 in highest-ever resolution - which is good news for drug developers & all of us who age...
Hygiene Breakthroughs Face Ridicule Before Saving Lives
Soap & disinfectants have saved more lives than any therapy Mother deaths before Semmelweis: ~10–15% After Semmelweis (1847):~1–2% Doctors laughed at him. He went to asylum & died from a beating Breakthroughs are ridiculed until they become part of everyday life