David Sinclair, PhD

David Sinclair, PhD

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Harvard geneticist; posts research, analyses, and interviews on aging biology and interventions.

New Team Targets Longevity Gap Amid Funding Shortfall
SocialMar 13, 2026

New Team Targets Longevity Gap Amid Funding Shortfall

Longevity research is being starved of funds just when the US needs to be more competitive. Have assembled a team working on it. Launch date: April 2026 https://t.co/DOgprwaSzv

By David Sinclair, PhD
Biology's Slow Validation: AI May Accelerate Breakthroughs
SocialMar 13, 2026

Biology's Slow Validation: AI May Accelerate Breakthroughs

In my experience, ideas that take seconds to conceive take years to confirm in the lab and 1–2 years to get published in a top journal. This is biology’s Achilles heel Let’s see if AI can fix that https://t.co/3On4DrTcU6

By David Sinclair, PhD
OSK Gene Combo Reverses Joint Damage via Epigenetics
SocialMar 8, 2026

OSK Gene Combo Reverses Joint Damage via Epigenetics

Osteoarthritis & back pain affects millions of people. Instead of managing symptoms, imagine rebuilding joints by making them young New study shows the reprogramming gene combo OSK regrows joints in mice & effect depends on TET2 so it's epigenetic...🧵 https://t.co/AlOIwcEXEQ

By David Sinclair, PhD
Whale Protein Boosts DNA Repair, Slowing Aging
SocialMar 8, 2026

Whale Protein Boosts DNA Repair, Slowing Aging

DNA breaks are a potent accelerator of epigenetic drift, which some researchers think drives aging. Great work by the Gorbunova lab 👏

By David Sinclair, PhD
UT San Antonio Awarded $38B ARPA-H Grant for Drug Trials
SocialMar 6, 2026

UT San Antonio Awarded $38B ARPA-H Grant for Drug Trials

UT San Antonio has been given a $38biin ARPA-H grant to study the health benefit effects of three drugs in humans, namely, rapamycin, dapagliflozin and semaglutide …🧵 https://t.co/fAX14ngoyD

By David Sinclair, PhD
Resveratrol Eases Neuropathic Pain via Mitochondrial Restoration
SocialMar 5, 2026

Resveratrol Eases Neuropathic Pain via Mitochondrial Restoration

Neuropathic pain affects 7-10% of all people globally. New 🐁 study finds resveratrol alleviates neuropathic pain associated with restoration of mitochondrial dynamics 👏 https://t.co/zJ8LvwZ9UP https://t.co/hdCK7UgqBj

By David Sinclair, PhD