Drug Discovery Expands Beyond AI to New Frontiers
The marked expansion of paths and methods for new drug development including and beyond AI @Joseph_C_Wu @james_y_zou @WuXuekun @ScienceMagazine https://t.co/hTJ4Rt181n https://t.co/H3U5BNR1ER
Prediction Markets Threaten Public Health, Says Science Magazine
Prediction markets like @Polymarket are a threat for public health, asserted in a @ScienceMagazine essay https://t.co/Kk2OOVrxHy https://t.co/1pGA9aiBAh
Super‑resolution Microscopy Visualizes Live‑cell Endoplasmic Reticulum
What does the endoplasmic reticulum look like in a live cell, thanks to super-resolution microscopy? @naturemethods https://t.co/HZ0Vf9ZpZa https://t.co/fT95huDwNP
Third‑generation T‑cell Engagers Advance Cancer Immunotherapy
Cancer immunotherapy keeps revving up. Now onto a 3rd generation of T cell engagers https://t.co/h05f8h3i8L https://t.co/PP5XE8WWDr
Anti‑amyloid Drugs Show Trivial, Non‑meaningful Cognitive Benefit
The effect of current anti-amyloid drugs vs Alzheimer's disease is "trivial" for cognitive function or dementia severity, not clinically meaningful, from a systematic @cochranecollab review of 17 trials, >20,000 patients https://t.co/9A6PeZOyAt https://t.co/c1PCOYZxws
New NEJM Review Links Hormone Therapy to Cardiovascular Risk
Sex hormones, clotting disorders, and cardiovascular risk An important new @NEJM review for MHT and testosterone latest data https://t.co/UNqXAwjsKM https://t.co/4ckJsc4YyE
Immune Activation Drives Neurodegenerative Disease Progression
On the path to neurodegenerative diseases, the pivotal role of immune system activation. A new and excellent review @jclinicalinvest https://t.co/4j2OwwHcJQ https://t.co/qCMJT8miXQ
Promolytics: Targeting Cancer‑Promoting Clones to Halt Progression
A new review on tumor promotion and the evolution of cancer with the concept of "promolytics" —drugs that could prevent potentially dangerous clones and/or their progression https://t.co/IFah5gi8ZK @Nature
Training LLMs on AI‑generated Text Creates Hidden Bias
What can happen when LLM models are trained on AI outputs? A potential hidden, bad influence https://t.co/UDGSalz98r https://t.co/RxGtmml55O
Inflammation: The Overlooked Key to Preventing CAD
That's right. Inflammation is the big miss for getting ahead of coronary artery disease https://t.co/KIs1AFxflE My review of this big shift https://t.co/foSaaTYUD4 https://t.co/cCRqSd8axt
Medical AI Flaws Exposed: Bad Chatbot Answers, Unreliable Data
Issues recognized with medical AI models —Problematic responses to 5 chatbots https://t.co/V6IZHOhAm4 —Prediction based on unreliable, open-access datasets https://t.co/PnJ0TrtXK2 https://t.co/Bp8ztckFgV
High Blood Glucose Linked to Cognitive Decline via Lactate Pathway
How do high glucose levels in the blood impair cognition and predict mild cognitive impairment in people with diabetes? @scisignal Elevated plasma lactate and related pathway, with a peptide intervention to potentially address it https://t.co/ai1369HWVU https://t.co/JcszZT2Tt2
Somatic Immune Cell Mutations Linked to Autoimmunity
New evidence that somatic mutations in immune cells can be the basis for autoimmune disease @Nature https://t.co/GvzxLYgvfw
RUNX1 Identified as Key to Rejuvenate Aging T Cells
Discovery of a factor (RUNX1) that pinpoints T cell senescence and restoring its functionality achieves T cell rejuvenation. Significant implications in older adults with loss of immune system protection. https://t.co/X58DvzIUXY @ImmunityCP https://t.co/hzL3zFiPMm
GLP‑1 Receptors Protect Liver in Mouse MASH Model
Adding to the GLP-1 drug weight-loss independent effect benefit : impact on liver sinusoidal endothelial cell GLP-1 receptors for liver protection in mouse MASH model @Cell_Metabolism @DanielJDrucker @ChusaGzlzRellan https://t.co/0A13QYgm05
