You Should Own Your Health Data Amid AI Race
Who owns your health data? It should be you. The AI arms race is making matters worse. feature @NatureMedicine https://t.co/7hKkmTW6fQ
Statins Save Lives, Yet Raise Diabetes and Myopathy Risks
I'm very pro-statins for their incontrovertible benefit vs atherosclerotic buildup and reduction of cardiovascular adverse events. Their benefits greatly overrides the risks. However, I always keep in mind 2 key side-effects: 1. Inducing Type 2 diabetes, uncommon, but more likely with aggressive...
New Nature Papers Hint at AI's Expanding Medical Role
AI in medicine is moving rapidly to take on much broader tasks than ever, some not fully envisioned. It's not proven in real medicine yet, but the results of the 2 new @Nature papers this week foreshadow where we may...
New Research Advances Medical Reasoning Toward Real-World Care
Yes, these new papers I reviewed are pushing toward medical reasoning in order to provide diagnosis to treatment care. Still in the simulation of practice phase, but moving towards tests in a real medical environment.
Aging Impairs Brain’s Waste‑Clearance Glymphatic Flow
Non-invasive imaging of the brain's glymphatic system, responsible for clearing waste products from the brain. Its flow gets impaired with aging, as shown in the mouse model @ScienceAdvances https://t.co/I6gczpjShm
AI Reads Brain Health From Retinal Photos
If you want to know a lot about a person's brain health, it's embedded in a retina photo, deciphered by AI https://t.co/3xN8k8R6CX @LancetDigitalH https://t.co/B4ucfC1Nek
New AI Models Deliver End-to-End Emergency to Outpatient Care
Today @Nature published 2 new AI medical agentic models that take capabilities to a new level, from end-to-end care after presentation to the emergency department and longitudinally through 3 out-patient visits. There's a lot to unpack. Summarized in a new Ground...
Resistance Training Cuts Women's Heart Disease Risk
In 2 large cohorts of women, resistance training was associated with reduction of cardiovascular disease, and additive to aerobic exercise and low sedentary time https://t.co/b8U7DiBf55 https://t.co/90ZZHK0EHB
Heat Shock Proteins Buffer Mutations, Explaining Variable Disease Risk
Why do some people with a pathogenic (disease-causing) mutation get hit and others are resilient? One explanation is heat shock proteins (like HSP90) , molecular chaperones that have a buffering, protective impact. https://t.co/actqJ0ucvI https://t.co/Kex1FgG1ME
Aging Weakens Immunity; Restore Without Autoimmunity
Our immune response loses its integrity and protection as we age. If we're going to promote healthspan, we'll need to counter that loss of function and, at the same time, avoid inducing autoimmune diseases A new @jclinicalinvest review, open-access...
Daraxonrasib's Pancreatic Cancer Success Signals Wider Oncology Wins
The recent impressive drug (daraxonrasib) success vs pancreatic cancer may presage a much broader set of wins. gift link @TheEconomist https://t.co/8bxGbwz6We https://t.co/mBiUIQMyDc
One‑Shot CRISPR Cures Hereditary Angioedema in Phase 3
A life-threatening inherited disease, hereditary angioedema, with striking benefit from one-shot CRISPR genome editing. Phase 3 randomized, double-blind trial results @NEJM today https://t.co/pT4fVgZcNP https://t.co/TveFMeK9ia
Study Shows Cancer Can Be Predicted Five Years Early
What if we could predict cancer 5+ years ahead and prevent it? A new landmark study shows the way https://t.co/vRpESU3j8D
DNMT3A Mutations Drive Hyper‑methylation, Accelerating Age‑related Diseases
Getting to the root of age-related diseases. By studying a rare accelerated aging genetic disorder, gain-of-function mutations of DNMT3A were found to be causal. DNA hyper-methylation was then linked to stem cells dysfunction and multiple age-related diseases (blood, bone, metabolic). Work...
IL‑17/IL7R Identified as Central Immune Disease Drivers
Interleukin-17 (IL-17 and its receptor, IL7R) is emerging as a key mediator in many immune-related diseases. Today @SciImmunology a superb review https://t.co/QjRc9cr9Wl https://t.co/86y5bM46p5