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Ming Tang

Ming Tang

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Bioinformatics director at AstraZeneca; science communicator who teaches genomics (YouTube channel 'Chatomics').

Recent Posts

Sex Chromosomes Cause Mapping Artifacts in Whole‑genome Sequencing
Social•Feb 22, 2026

Sex Chromosomes Cause Mapping Artifacts in Whole‑genome Sequencing

1/ Sex chromosomes are bias magnets in WGS. Early large-scale genomes often showed weird copy-number or coverage patterns on X and Y that looked like biology, but were really mapping artifacts. https://t.co/YnApmtxHqm

By Ming Tang
RNA‑seq Batch Effects Can Fabricate False Biological Results
Social•Feb 21, 2026

RNA‑seq Batch Effects Can Fabricate False Biological Results

1/ RNA‑seq batch effects are one of the easiest ways to fool yourself in genomics. They can create beautiful, completely wrong biology if you’re not careful. https://t.co/VBtySwZHVL

By Ming Tang
Neutrophil Phenotypes and Spatial Patterns Mapped in Colorectal Cancer
Social•Feb 20, 2026

Neutrophil Phenotypes and Spatial Patterns Mapped in Colorectal Cancer

Single-cell integration and multi-modal profiling reveals phenotypes and spatial organization of neutrophils in colorectal cancer https://t.co/0FLusa7vuB https://t.co/8MswWoLhCa

By Ming Tang
Group 3 Medulloblastoma Shows Diverse Lipid Dependencies
Social•Feb 19, 2026

Group 3 Medulloblastoma Shows Diverse Lipid Dependencies

Multiomic integration reveals tumoral heterogeneity of lipid dependence within lethal group 3 medulloblastoma https://t.co/tpjJiRa08t https://t.co/z7aIYerTqO

By Ming Tang
Intronic Reads in Bulk RNA‑seq: Common and Multi‑Faceted
Social•Feb 19, 2026

Intronic Reads in Bulk RNA‑seq: Common and Multi‑Faceted

Why are there intronic reads in your bulk RNA-seq data? You're not alone—it's common, and the reasons are more layered than you think. Let’s break it down. 🧵 https://t.co/SNJnohqHUM

By Ming Tang
V‑plot TF Binding May Be Artifact of Fragmentation
Social•Feb 18, 2026

V‑plot TF Binding May Be Artifact of Fragmentation

🧵 That V-plot showing transcription factor binding? It might be an artifact. New research shows chromatin fragmentation methods create patterns even on naked DNA. Here's what went wrong. https://t.co/79B5c0ulgD

By Ming Tang
Claude Code Fabricates Fake ENSEMBL IDs for Gene Plots
Social•Feb 18, 2026

Claude Code Fabricates Fake ENSEMBL IDs for Gene Plots

1/ Claude Code just hallucinated ENSEMBL IDs for my volcano plot. (it happened last week for real) I asked it to highlight specific genes. The data matrix uses ENSEMBL identifiers. Instead of flagging that it couldn't map the gene symbols, it invented...

By Ming Tang
10 Free Bioinformatics Tools to Save Time & Money
Social•Feb 18, 2026

10 Free Bioinformatics Tools to Save Time & Money

🧵 10 free bioinformatics tools you should know in 2026. These will save you time, money, and headaches. https://t.co/t8amdLE4MX

By Ming Tang
BRD4's Extra‑terminal Domain Drives Recruitment to ASXL1 Targets
Social•Feb 17, 2026

BRD4's Extra‑terminal Domain Drives Recruitment to ASXL1 Targets

Recruitment of BRD4 to the ASXL1 genomic targets depends on the extra-terminal domain of BRD4 https://t.co/sRbcAAMqPx https://t.co/IbD0EM56SS

By Ming Tang
Retrieve Mouse Gene Lengths with Bioconductor TxDb
Social•Feb 17, 2026

Retrieve Mouse Gene Lengths with Bioconductor TxDb

🧵 Need gene lengths for every mouse gene? Bioconductor annotation packages make this simple. Here's how to get gene lengths using TxDb.Mmusculus and https://t.co/FiqDAsSPa0.db. https://t.co/VyE36hp3om

By Ming Tang

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