What's happening: Cell‑free PL‑display platform accelerates peptide screening ten‑fold
Researchers at the Innovation Center of NanoMedicine unveiled PL‑display, a cell‑free system that immobilizes individual peptides on magnetic beads, delivering more than ten‑fold efficiency gains versus traditional cell‑based displays. The method remains functional under high‑temperature, high‑salt and toxic‑protein conditions, broadening screening capabilities.
Also developing:

Hims & Hers reported Q4 results after the bell, with mixed performance, drawing investor focus on its GLP‑1 program and forward guidance. The company posted EPS of $0.08, double expectations, but revenue of $617 million fell short of the $619 million forecast. For Q1, guidance of $600‑$625 million disappointed analysts who had modeled $654 million, reflecting pressure from GLP‑1 price erosion and regulatory scrutiny. Analysts Christine Short highlighted a 30%+ growth in the core sexual‑health and dermatology segments, noting that only a small fraction of the 2.5 million subscribers use GLP‑1. Brian Tanquilut reiterated a “hold” rating, citing the Novo Nordisk patent lawsuit and the fading GLP‑1 halo as near‑term valuation caps, while emphasizing the company’s shift toward a holistic, personalized‑medicine model. The market’s initial sell‑off has softened as investors reassess the pivot away from GLP‑1 dependence. However, ongoing legal liabilities and uncertain GLP‑1 pricing dynamics keep the stock’s upside limited, making execution of the broader telehealth strategy critical for long‑term growth.
Researchers at the Innovation Center of NanoMedicine unveiled PL‑display, a cell‑free platform that immobilizes individual peptides on magnetic beads for rapid screening. The method delivers over ten‑fold efficiency gains versus traditional cell‑based displays and can operate under high‑temperature, high‑salt, or...

GoodRx introduced GoodRx Employer Direct, a new service allowing employers to directly subsidize the manufacturer‑sponsored price of high‑cost brand medications such as GLP‑1 drugs without adding them to health‑plan formularies. The model, first piloted with retailer Hy‑Vee, lets employers contribute...

In this episode, the hosts dissect why investors misunderstand Hims & Hers' (HEMS) gross margin potential, emphasizing that as a compounder without its own API manufacturing, HEMS cannot achieve margins higher than drug manufacturers. They illustrate how HEMS' margin trajectory...

This week’s coverage juxtaposes longevity hype with emerging science, highlighting David Sinclair’s bold claim that aging could be reversed within 10‑20 years, a new Nature paper confirming adult hippocampal neurogenesis, and research showing men lose the Y chromosome as they...

Epic Systems announced its first pharmaceutical customer, Eli Lilly, for the newly launched Epic Discovery platform. The deal marks the inaugural sale of a Health Grid product to a life‑sciences firm, allowing Lilly to streamline clinical trial creation, site identification, activation,...
A phase‑2 trial of relmacabtagene autoleucel (relma‑cel), a CD19‑directed CAR‑T therapy, enrolled 59 Chinese patients with relapsed/refractory mantle‑cell lymphoma after BTK‑inhibitor failure. The study reported a 71.2% overall response rate and a 59.3% complete response rate, with median time to...
A new analysis quantifies the operational and financial benefits of using Genmab’s epcoritamab, a dual‑indication bispecific antibody, for both relapsed/refractory diffuse large B‑cell lymphoma (DLBCL) and follicular lymphoma (FL). In a community‑practice model of 100 patients, the study projects 3,110...
A phase‑2b trial enrolling 94 adults with chronic hand eczema (CHE) without etiologic pre‑selection uncovered a mixed immune signature spanning type 2, type 3 and type 1 pathways. Dupilumab, an IL‑4Rα antagonist, delivered a 59.8% mean improvement in modified Total Lesion Symptom Score...

This week’s Endpoints Weekly highlighted a surge of GLP‑1 developments, including new trial data and expanded indications that reinforce the class’s dominance in obesity and diabetes treatment. The newsletter also released its annual Top 100 venture investors list, showing a notable...
The EMA’s Committee for Medicinal Products for Human Use (CHMP) recommended six new medicines, including three orphan drugs already approved by the FDA—Ojemda for pediatric low‑grade glioma, Palsonify for acromegaly, and Xolremdi for WHIM syndrome. The agency also gave a...
BioCentury’s cookie policy details five categories of cookies—strictly necessary, functional, marketing, advertising, and analytics—each serving distinct purposes on its website. Strictly necessary cookies support authentication, registration, and navigation, while functional cookies enable personalization of services. Marketing and advertising cookies help...

In episode 50 of the Life Sciences Today podcast, host Danny Lieberman sits down with Carol Pesner, CTO and co‑founder of ProtAI, to discuss the company’s AI‑driven approach to drug discovery. ProtAI fuses structural proteomics with advanced artificial intelligence to...

The World Health Organization convened an information meeting to finalize the composition of the 2026‑27 Northern Hemisphere influenza vaccine. Senior officials, including Dr. Chikui Hikawazu and Dr. Maria Van Kokov, highlighted the critical role of the Global Influenza Surveillance and...
Human pluripotent stem cells (hPSCs) are emerging as a transformative platform for Parkinson’s disease, with recent phase I/II trials showing successful engraftment of hESC‑ and iPSC‑derived dopaminergic neurons. Yet extensive data reveal that cultured hPSCs frequently acquire recurrent genetic lesions—most...
Autosomal dominant polycystic kidney disease (ADPKD) remains the most common hereditary cause of chronic kidney disease, imposing substantial morbidity, mortality, and healthcare costs worldwide. Recent advances in molecular genetics and high‑resolution imaging have sharpened diagnostic criteria and enabled more accurate...

Minnesota’s Department of Health reports that hospitals and clinics in the state earned at least $1.34 billion in 2024 from the 340B drug discount program. Participants received $3.045 billion in discounted medicines but paid $1.53 billion plus $165 million in administration fees. The largest...
Researchers at Cornell’s Weill Institute introduced QUASARR‑seq, a high‑throughput assay that measures promoter and enhancer activity simultaneously. The study found that most human regulatory elements can function as both promoters and enhancers, following a unified regulatory logic. A bidirectional feedback...

Cigna announced the acquisition of CarepathRx, a private‑equity‑backed pharmacy that supplies prescription drugs to roughly 10% of U.S. hospitals. The deal expands Cigna’s vertical integration in the pharmaceutical supply chain, complementing its earlier purchase of Express Scripts.

Japanese drugmaker Asahi Kasei announced it will acquire German biotech Aicuris for €780 million, gaining its antiviral therapy pritelivir targeting HSV. The deal expands Asahi Kasei's anti‑infectives portfolio and supports its goal of reaching JPY 300 billion in pharma sales by 2030.

Joseph Wu, a Stanford professor of medicine and radiology, leads the Stanford Cardiovascular Institute in developing patient‑specific cardiac cells derived from a person’s own blood. By reprogramming blood cells into pluripotent stem cells and then coaxing them to become beating...

At MedTech World Middle East 2026, Prof. Christian Scerri unveiled a plan to turn Malta into a living lab for precision oncology, leveraging its single national health system, compact ecosystem, and EU‑aligned regulatory framework. He outlined a roadmap that includes...

At MedTech World Middle East 2026, a panel of GCC health leaders highlighted the region’s rapid shift from a pure healthcare consumer to a burgeoning hub for MedTech, biotech, and digital health innovation. National visions and transformation strategies are driving...

Citi’s research team issued a bearish stance on Dr Reddy’s Laboratories, citing concerns that the company’s generic version of semaglutide may not capture significant market share. In contrast, CLSA upgraded Hindustan Aeronautics Limited (HAL) to a preferred pick, highlighting its strongest...

GlaxoSmithKline (GSK) announced the acquisition of privately held 35Pharma, a developer of a pulmonary arterial hypertension drug. The cash deal is valued at just under $1 billion, expanding GSK’s pipeline in respiratory and immunology.

The podcast examines a new Health Affairs paper that tracks how the Inflation Reduction Act’s Medicare drug‑price negotiation provision has affected biopharmaceutical clinical‑trial activity. Dr. So Young Kang and co‑authors compare industry‑sponsored trial initiations from 2015‑2024, focusing on firms directly hit...

The discussion centers on the emerging complexities of conjugated lipid nanoparticle (LNP) manufacturing, a shift from standard platform processes toward targeted RNA delivery. Sujit explains that adding a biologic ligand to LNPs forces manufacturers to revisit every process parameter—viscosity, shear...

The panel examined the emerging “active” delivery paradigm for lipid nanoparticle (LNP) therapeutics, focusing on the added layers of complexity introduced by ligand‑modified formulations and the need for robust R&D pipelines. Participants contrasted passive LNPs with active, ligand‑decorated versions, highlighting...