Lifespan.io

Lifespan.io

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Nonprofit covering aging research, clinical progress, and longevity biotech.

When Doctors Prescribe Horoscopes: The Trouble With Biological Age Tests
NewsMar 23, 2026

When Doctors Prescribe Horoscopes: The Trouble With Biological Age Tests

Consumer epigenetic "biological age" tests promise a single number that reflects a person’s true health trajectory, but they actually measure DNA methylation patterns correlated with chronological age. Research‑grade clocks can predict mortality risk, yet the kits sold to patients lack...

By Lifespan.io
Using mRNA to Fight Tau Aggregation in Alzheimer’s
NewsMar 19, 2026

Using mRNA to Fight Tau Aggregation in Alzheimer’s

Researchers have engineered a lipid nanoparticle (PLNP) that mimics acetylcholine to deliver TRIM11 mRNA across the blood‑brain barrier and dismantle tau aggregates. In vitro, PLNP achieved 17‑fold higher mRNA uptake than conventional LNPs, and in transgenic Alzheimer’s mice it eliminated...

By Lifespan.io
Xplore Program 2026: A Remote Summer Fellowship in Longevity
NewsMar 12, 2026

Xplore Program 2026: A Remote Summer Fellowship in Longevity

Longevity Xplorer (LongX) has opened applications for its 2026 Xplore Program, a fully remote summer fellowship that bridges the gap between academic interest in aging and hands‑on work in longevity biotech. The nine‑week curriculum combines a month of intensive biology...

By Lifespan.io
Vitalist Bay 2026 Returns to Berkeley May 14–17
NewsMar 12, 2026

Vitalist Bay 2026 Returns to Berkeley May 14–17

Vitalist Bay 2026, the world’s largest longevity festival, returns to Berkeley’s Lighthaven campus from May 14‑17. The four‑day event consolidates six thematic tracks—Biotech, Investors, Replacement, Longevity Science, AI × Bio, and Biostasis—and features more than 60 top researchers, founders, and clinicians as...

By Lifespan.io
The Many Dangers of 7-Ketocholesterol
NewsMar 12, 2026

The Many Dangers of 7-Ketocholesterol

Researchers led by Matthew O’Connor have published a comprehensive review of 7‑ketocholesterol (7KC), an oxidized cholesterol formed by reactive oxygen species. The paper details how 7KC accumulates in atherosclerotic plaques, transforms macrophages into inflammatory foam cells, and exerts neurotoxic effects...

By Lifespan.io
Fat Composition Affects T Cell-Mediated Immunity
NewsMar 6, 2026

Fat Composition Affects T Cell-Mediated Immunity

Scientists discovered that the ratio of polyunsaturated to monounsaturated fatty acids in the diet determines T‑cell susceptibility to ferroptosis, a form of iron‑dependent cell death. Mice fed diets with low PUFA/MUFA ratios showed higher ferroptosis resistance, leading to stronger humoral...

By Lifespan.io