
Cellbricks Secures $10M
Berlin‑based Celicks announced a $10 million financing round aimed at accelerating its proprietary 3D bioprinting platform for vascularized tissue implants. The capital will fund the transition of its lead programs from pre‑clinical studies into early‑stage clinical trials, positioning the startup at the forefront of regenerative‑medicine research. Celicks’ technology prints living tissue with built‑in blood‑vessel networks, addressing the long‑standing bottleneck of vascularization that has limited the viability of engineered organs. By creating functional, perfusable constructs, the company hopes to offer an alternative to donor grafts for organs such as kidneys, livers, and endocrine glands, which are critical in both standard and longevity‑focused medicine. The founder emphasized that “functional tissue replacement is a genuine bottleneck in longevity medicine,” noting that even with anti‑aging interventions, organ failure remains inevitable without viable substitutes. Successful vascularization could therefore shift the trajectory of age‑related organ decline and expand therapeutic options beyond scarce donor organs. If Celicks validates its approach in humans, the implications are profound: reduced reliance on organ donation, accelerated drug development pipelines that require human‑like tissue models, and a new market segment for personalized regenerative therapies. Investors and healthcare systems alike will watch closely as the company moves toward clinical validation.

Eli Lilly’s Longevity Bet
Eli Lilly is quietly reshaping its R&D agenda, moving from a narrow GLP‑1 obesity play toward a broader longevity strategy. The company’s recent moves signal an ambition to become a “big farmer” of age‑related therapeutics, even if the term does not...

Early Brain Screening Expands
Premas, a neuro‑tech firm, has announced a partnership with Health is One to roll out its early‑brain‑screening platform across the health‑system network. The initiative focuses on detecting neurodegenerative disease risk factors before patients exhibit any clinical signs. The screening leverages proprietary...
Curve Bio Strengthens Clinical Push with CMO Hire
Curve Biosciences, the whole‑body intelligence company, announced the appointment of hepatology expert Dr. Amit Singal as chief medical officer. The hire follows a $40 million financing round and signals the firm’s shift from platform development to clinical implementation, starting with liver...
Occupational Health Meets Longevity
Occupational health is evolving from a compliance‑focused function to a preventive longevity platform, aiming to influence how employees age. Executives are urged to prioritize five key areas, including midlife interventions, data‑driven health monitoring, and navigating privacy challenges. Employers see longevity...

Can Aging Be Treated Like a Disease? | Longevity News Roundup — Week 14, 2026
The Longevity Technology Unlocked episode spotlights four converging developments: PMAZ’s partnership with Health is One to roll out an early‑brain‑screening platform, Eli Lilly’s expanding multi‑pathway longevity portfolio, Berlin‑based Cell Bricks securing $10 million for vascularized bioprinted tissue implants, and coordinated global rallies...
Prediabetes May Need a Tailored Treatment Rethink
Researchers presented new data on 662 U.S. adults aged 18‑40 with prediabetes, revealing that the average five‑year risk of progressing to type 2 diabetes is 7.5%. The risk climbs to 10.9% for those meeting GLP‑1 receptor agonist (GLP‑1RA) weight‑loss criteria, 15.1%...
Superpower Partners with Grail to Add Galleri Cancer Screening
Superpower, a technology‑driven health benefits platform, announced a partnership with Grail to incorporate the Galleri multi‑cancer blood test into its member offerings. Galleri screens for more than 50 cancer types using DNA methylation signatures and has received FDA clearance for...
Well Health Partners with AliveCor for Cardiologist Review
Well Health has teamed with AliveCor to embed Canadian‑registered cardiologists into the Kardia app’s AI‑driven ECG workflow. Canadian users can now request a Clinician Review, receiving a written physician interpretation within 24 hours. The service leverages Health Canada‑cleared AI algorithms...
Designs for Health Launches NeuroCalm Peptide for Gut-Brain Support
Designs for Health has introduced NeuroCalm Peptide, a once‑daily capsule formulated to support the gut‑brain axis. The product combines the milk‑derived peptide Lactium with heat‑treated Lactobacillus gasseri CP2305, a postbiotic shown to influence stress markers. Clinical data cited by the...
Annovis Wins US Patent for Buntanetap in Brain Infection Injuries
Annovis Bio has been granted a United States patent for its compound Buntanetap, specifically covering its use in treating brain infection‑related injuries. The patent expands the drug's previously explored Alzheimer’s indication to a novel therapeutic area. This intellectual‑property win bolsters...
SpectraCell Packages Longevity, Early Disease Detection in One Kit
SpectraCell Laboratories introduced Baseline Nexus, a bundled diagnostic kit that merges four flagship tests—micronutrient profiling, lipoprotein particle analysis, telomere length measurement, and MTHFR genotyping—into a single service. The package aims to reveal hidden nutrient deficiencies, cardiovascular risk, biological aging, and...
Rhythm Posts First FDA Approval for Acquired Hypothalamic Obesity
Rhythm Pharmaceuticals announced FDA approval of IMCIVREE (setmelanotide) as the first therapy for acquired hypothalamic obesity, covering adults and children aged four and older. The decision follows the Phase 3 TRANSCEND trial, which demonstrated an 18.4% mean BMI reduction versus placebo...
Annovis Publishes Historical Review of Buntanetap
Annovis released a historical review of its investigational drug Buntanetap in The Scientist, charting its evolution from a 19th‑century execution poison to a modern candidate for Alzheimer’s and Parkinson’s disease. The article details discovery, mechanism elucidation, chemical optimization, and progression...
Humanaut to Open Dallas Clinic, Launches Founding Membership Presale
Humanaut announced the opening of its first flagship clinic in Dallas, Texas, alongside a founding membership presale. The clinic will deliver metabolic profiling, continuous glucose monitoring, and AI‑driven health coaching under a $5,000 annual membership. The presale targets $10 million to...
Agentis, Ultrahuman Tie Wearables to Longevity Quotient
Agentis Longevity and Ultrahuman announced a strategic partnership to fuse Ultrahuman’s real‑time wearable and continuous glucose monitoring data with Agentis’ proprietary Longevity Quotient (LQ) score. The combined platform will deliver a continuous health score that translates biosensor readings into actionable...
I-Lumen Receives FDA IDE to Start US I-SIGHT2 Enrollment
I‑Lumen announced that the U.S. Food and Drug Administration has granted an Investigational Device Exemption (IDE) for its i‑SIGHT2 clinical study. The clearance allows the company to begin enrolling participants in the United States to evaluate its breath‑based metabolic monitoring...
Kailera Plots IPO to Fuel Obesity Pipeline
Kailera Therapeutics, after raising $1 billion across a $400 million Series A and $600 million Series B, is preparing an IPO to fund its obesity drug pipeline. Its lead candidate, ribupatide, has delivered up to 23.6% weight loss in Phase 3 injectable trials and 12.1% loss...
20/20 BioLabs Expands Longevity Test with Kidney Risk Tech
20/20 BioLabs announced an exclusive U.S. license with South Korea’s ROKIT Healthcare to embed its chronic kidney disease (CKD) prediction algorithm into the company’s OneTest for Longevity platform. The addition expands the test beyond inflammation biomarkers to provide early kidney...
Enlivex Clears Pivotal FDA Hurdle in Knee Osteoarthritis
Enlivex has secured FDA Investigational New Drug (IND) clearance to launch a global Phase 2b trial of its immunotherapy Allocetra for moderate‑to‑severe age‑related knee osteoarthritis. The study will be randomized, double‑blind, and placebo‑controlled, building on promising Phase 1/2a data from 134 patients....
Anavex Updates Regulatory Strategy for Blarcamesine
Anavex Life Sciences has withdrawn its European Union marketing authorization application for blarcamesine and will collect additional data while maintaining dialogue with the European Medicines Agency. The company has concurrently submitted new data to the U.S. FDA to explore a...
Insilico Medicine, Lilly Partner on AI-Driven Drug Discovery Deal
Insilico Medicine and Eli Lilly have entered a partnership to use Insilico’s AI‑driven Pharma.AI platform for discovering new oral therapeutics across several disease areas. Lilly receives an exclusive worldwide license to develop, manufacture and commercialize the preclinical candidates, while Insilico secures...
New Data Show TrenibotE Safety in Repeat Treatments
Allergan Aesthetics presented new Phase 3 data on its investigational neurotoxin TrenibotE at the 2026 American Academy of Dermatology meeting. The open‑label study evaluated up to three repeat glabellar line treatments, confirming a consistent safety profile, no neutralizing antibodies, rapid onset...
Can Medicine Outrun Aging? Gerontologist Says Odds Are Improving
Longevity Escape Velocity (LEV) founder Aubrey de Grey discussed the concept of outpacing aging on the Longevity Technology Unlocked podcast. He described LEV as repairing molecular damage to rejuvenate individuals, buying decades for further research, and highlighted mouse studies combining...
AI-Built Intrabodies Target Alzheimer’s Within
University of Essex researchers used artificial intelligence to redesign antibody fragments, creating "intrabodies" that remain stable inside human cells. By adjusting electrical charge, they converted 672 antibodies into intracellularly functional molecules that bind disease‑causing proteins linked to Alzheimer’s, Parkinson’s, Huntington’s...
Subtle Antiaging Injectables Become Allergan’s Next Bet
At AMWC 2026, Allergan Aesthetics announced a strategic pivot toward “undetectable” hyaluronic‑acid injectables, emphasizing subtle, personalized maintenance rather than dramatic transformation. The company released a consumer study of 12,000 respondents showing over 70% prefer natural‑looking, reversible results. Allergan frames this...
Diabetes Eye Damage Linked to Higher Dementia Risk
New research published in the American Journal of Ophthalmology tracked nearly 770,000 older adults and found that type 2 diabetes patients with worsening diabetic retinopathy face a markedly higher risk of dementia. Those with the most severe retinal disease had...
Alterity Receives Positive FDA Feedback on ATH434 Phase 3 Program
Alterity Therapeutics received positive written feedback from the U.S. Food and Drug Administration after a Type C meeting on its planned Phase 3 program for ATH434 in Multiple System Atrophy. The agency endorsed the company’s clinical pharmacology and non‑clinical development strategy and...
Private Clinics Face Longevity Learning Curve
Longevity medicine is moving from niche research into private clinics, where providers are experimenting with layered diagnostics such as genomics, imaging and deep blood panels. The Longevity Show’s new blog outlines the challenges these clinics face, including the lack of...
PREMAZ Expands Early Brain Screening Through Health Is One
PREMAZ, a Cambridge‑backed digital cognitive assessment, has partnered with UK wellness provider Health is One to embed early brain‑health screening into everyday well‑being services. The 10‑15 minute test focuses on "memory precision," detecting subtle declines that traditional tests miss. By...
Global Rallies Call for Aging to Be Treated
Fund Longevity is staging coordinated rallies in 14 cities to pressure governments into funding geroscience and recognizing aging as a treatable medical condition. The demonstrations underscore a widening gap: private capital is pouring billions into senolytics, cellular reprogramming and AI‑driven...
Lilly Races to Become First Longevity Big Pharma
Eli Lilly has signed a deal with AI‑focused biotech Insilico Medicine valued up to $2.75 billion, with $115 million paid upfront and the remainder tied to milestones. The agreement grants Lilly an exclusive worldwide license to several preclinical oral candidates and access...
Allergan Aesthetics Highlights Undetectable Era for HA Injectables
Allergan Aesthetics, an AbbVie subsidiary, announced the "undetectable era" for hyaluronic acid (HA) injectables at the Aesthetic & Anti-Aging Medicine World Congress 2026 in Monaco. The company unveiled its global research study, "Layered Beauty: The New Aesthetic Mindset," which highlights...
Insilico, Tenacia Expand AI-Driven CNS Collaboration
Insilico Medicine and Tenacia Biotechnology have broadened their AI‑driven collaboration to create additional small‑molecule therapies for central nervous system disorders. Building on a March 2025 program that combined Insilico’s Pharma.AI platform with Tenacia’s proprietary data, the partners will use generative...
New AI Research Reshapes Neuroprotective Drug Discovery Funding
BCC Research’s new Pulse report, “AI Impact on Neuroprotective Agents,” outlines how artificial intelligence is reshaping the discovery, development, and delivery of neuroprotective therapies. The study projects a 4.5% CAGR for the North American market through 2030 and documents hundreds...
Scalable Biotech Manufacturing Targets $14B Cell Therapy Market
Research forecasts the global cell‑therapy manufacturing market to exceed $7 billion in 2026 and reach $14 billion by 2035. The FDA has introduced new manufacturing flexibility to accelerate approval timelines for cell and gene therapies, addressing a capacity bottleneck that analysts expect...

Mortality Trends in Gen X & Millennials
The video highlights a new longitudinal study that tracks cause‑of‑death data from 1979 through 2023, revealing that people born between 1970 and 1985 – the tail end of Generation X and the early Millennials – are experiencing higher mortality rates...

Are We Managing Women’s Health All Wrong?
The Longevity Technology Unlocked episode challenges the prevailing male‑centric approach to health by spotlighting women’s unique hormonal cycles, metabolic needs, and social biology. Hosts Dr. Nina Patrick, Dr. Laura Briden, and Dr. Molly Malof argue that conventional hormonal birth control...

Peptides Target “Undruggable” Diseases
Santa Cruz‑based company specializing in unnatural macrocyclic peptide therapeutics announced a $45 million Series B round and a $1.7 billion collaboration with Novartis. The partnership targets cardiovascular proteins that have eluded conventional small‑molecule and antibody approaches. The firm positions macrocyclic peptides between traditional small...

Focus on What Counts
The video "Focus on What Counts" outlines a practical framework for applying the 80/20 rule to personal and professional priorities, urging viewers to distill their objectives into a “focus five” each quarter. The speaker explains how to rank the five items,...

How Can You Turn Your Stress Into Advantage?
The Longevity Technology Unlocked episode tackles how stress can be reframed from a purely damaging force into a lever for vitality, drawing on neuroscience, eastern practices, and emerging wearables. Hosts Dr. Nina Patrick and Phil Newman interview Dr. Pedram Sojai,...
MBX Biosciences Reports 2025 Results and Advances Endocrine Pipeline
MBX Biosciences released its fourth‑quarter and full‑year 2025 results, reporting a net loss of $87 million, up from $61.9 million in 2024, as R&D spending climbed to $79.2 million. The company confirmed that its lead candidate canvuparatide for chronic hypoparathyroidism cleared a Phase 2...
Pretzel Therapeutics Presents PX578 Data Supporting POLG Disease Treatment
Pretzel Therapeutics presented preclinical data for its investigational small‑molecule PX578 at the 2026 MDA Clinical and Scientific Conference. The drug is designed to activate the mitochondrial DNA polymerase gamma (POLG) and restore mitochondrial DNA levels in patients with mitochondrial DNA...
Revive Expands Access to Physical Therapy via Orbit Telehealth Partnership
Revive Health announced a partnership with Orbit Telehealth to deliver virtual physical‑therapy services nationwide. The collaboration integrates Revive’s evidence‑based PT protocols with Orbit’s HIPAA‑compliant video platform, enabling clinicians to treat patients remotely. Launching in Q3 2024, the joint offering aims...
Clene Reports Full Year 2025 Results with ALS Drug Progress
Clene Inc reported FY2025 results, cutting its net loss to $26.2 million and holding $5.2 million in cash after a $28 million oversubscribed direct offering. Revenue stayed minimal at $200,000 as the company concentrates on its lead candidate, CNM‑Au8, which showed significant biomarker...
Serotonin Centers Unveils Medical Longevity Model for Fitness Industry
Serotonin Centers announced the Serotonin Partner Program, a medical longevity model for U.S. fitness facilities. The turnkey platform lets gyms add medically supervised services—weight loss, hormone optimization, peptide and NAD+ therapies, IV metabolic support—within dedicated longevity suites. Serotonin funds, staffs,...
Theriva Biologics Reports 2025 Results and Pipeline Progress
Theriva Biologics closed 2025 with $13.1 million in cash, rising to $15.2 million by February 2026, enough to fund operations into the first quarter of 2027. The company reported a net loss of $25.3 million, a modest improvement as R&D spend fell while...

MindImmune Lands ADDF Funding to Harness the Immune System Against Alzheimer’s
MindImmune Therapeutics secured a $5 million investment from the Alzheimer’s Drug Discovery Foundation to advance its lead candidate, MITI‑101, which targets peripheral immune pathways implicated in Alzheimer’s neuroinflammation. Unlike conventional amyloid‑ or tau‑focused approaches, the Cambridge‑based biotech aims to block CD11c‑positive...

The Mouth-Body Connection: Why Oral Health Matters for Longevity
The Longevity.Technology UNLOCKED episode highlights the mouth as a pivotal gateway to overall health, linking nasal breathing, oral microbiome, and dental habits to inflammation, sleep quality, and metabolic function. Clinicians Dr. Aoife Stack and Dr. James Goolnik argue that chronic...

Forever Young Explores the Longevity Revolution
The documentary "Forever Young" arrives as the longevity field moves from lab breakthroughs to public policy and everyday life. Featuring top geroscientists from the Buck Institute, Harvard and Stanford, the film argues that lifestyle and environment outweigh genetic destiny in...