GLP‑1 Weight Loss Drugs Lower HRV, Raise Heart Rate
Reducing body weight with GLP-1 agonists isn't a free lunch: negative impacts on HRV, RHR GLP-1 receptor stimulation depresses heart rate variability and inhibits neurotransmission to cardiac vagal neurons https://t.co/4QNy141TtK
Senolytics Fail to Reset Senescence DNA Methylation Marks
DNA Methylation Signatures of Cellular Senescence Are Not Reversed by Senolytic Treatment https://t.co/uemETuWkqI H/T @NataliaMitin
Higher Plasma Choline and Betaine Linked to Better Cognition
Plasma free choline, betaine and cognitive performance: the Hordaland Health Study | British Journal of Nutrition | Cambridge Core - https://t.co/3xnGTbju80
Blood and Fat Markers Forecast Heart Disease Risk
Neutrophil-to-Lymphocyte Ratio, Bone Marrow, and Visceral Fat Metabolism as Predictors of Future Cardiovascular Disease in an Asymptomatic Healthy Population https://t.co/Oq1a3fH5qa
Immune‑Inflammatory Balance Linked to Extreme Longevity
Immune-Inflammatory Response in Lifespan—What Role Does It Play in Extreme Longevity? A Sicilian Semi- and Supercentenarians Study https://t.co/UPfK7vrIUT #mdpibiology
Rejuvenated CD4 T Cells Promote Longevity, Infections Accelerate Senescence
Rejuvenated CD4 T cells--> longevity https://t.co/FH5XTQc3zl On the other hand, infection-->increased senescent T cells, shorter lifespan? https://t.co/wtsDnmIdnh
Epigenetic Aging Rate Outperforms 13 Biomarkers in Mortality Prediction
Comparing fourteen consensus biomarkers of aging: epigenetic pace of aging as the strongest predictor of mortality in BASE-II https://t.co/q9jmoubgex
Blood‑based ECM Protein Clock Predicts Biological Age and Disease
An Extracellular Matrix Aging Clock Based on Circulating Matrisome Proteins Predicts Biological Aging and Disease https://t.co/3VOwhGCz5S
Wheat Bran Plus Resistant Starch Improves Fecal Health Markers
Combining wheat bran with resistant starch has more beneficial effects on fecal indexes than does wheat bran alone https://t.co/c5q4PlNB2l
Certain Fibers Boost Colonic Sugar Fermentation in Obesity
Ha, it may seem like an esoteric subject, but I'm hot on the trail of something Specific dietary fibers steer toward distal colonic saccharolytic fermentation using the microbiota of individuals with overweight/obesity https://t.co/6b8y6du2On
Mitochondrial Transplantation Reverses Cell Degeneration
In terms of my top bets for rejuvenation-based therapies, mitochondrial transplanation has entered the chat Cell-type-targeted mitochondrial transplantation rescues cell degeneration https://t.co/izvDaRk7kz
Bergamottin Reduces Cancer‑related Cachexia via Multiple Pathways
A Novel Role of Bergamottin in Attenuating Cancer Associated Cachexia by Diverse Molecular Mechanisms https://t.co/pr3d4kg0hB #mdpicancers
Natural Compounds Boost Gut Butyrate, Increase Muscle Mass
Computational Screening and Experimental Validation of Natural Compounds that Enhance Butyrate Production in Gut Bacteria and Promote Muscle Cell Mass https://t.co/YgZdtWly4n
EMF‑Controlled Gene Switch Reverses Aging In Vivo
EMF-inducible gene switch gene switch enables in vivo rejuvenation by reversing aging phenotypes Electromagnetic field-inducible in vivo gene switch for remote spatiotemporal control of gene expression https://t.co/yeIDzXChWV
Grapefruit Compound Bergamottin Blocks STAT3, Triggers Tumor Cell Death
Bergamottin, a natural furanocoumarin obtained from grapefruit juice induces chemosensitization and apoptosis through the inhibition of STAT3 signaling pathway in tumor cells https://t.co/cLRxHMFBCJ