Senescent immune cells protect against damage, inflammation and disease 🤯 In mice, p16-expressing immune cells delay age-related organ deterioration and preserve tissue homeostasis. More evidence of the physiological roles of senescent cells? https://t.co/UtBKDF00P1
Aging may or may not be classified as a disease, but that’s largely semantics. What matters is that aging is a malleable, targetable biological process, and slowing human aging would result in massive health benefits.
Great to see a new work showing that C1ORF112 is upregulated in tumor tissues and that it promotes breast cancer proliferation. We computationally predicted C1ORF112 to be related to cancer back in 2012, and we were the first to study and...
The incredible study using "Rivers of telomeres" to rejuvenate tissues and extend lifespan in mice is now undergoing open peer-review. I did a review, pointing out issues with the methods and the lifespan curves. They're looking for more reviewers. https://t.co/KOiR4F85sT

Aging underpins most chronic diseases and remains the biggest challenge to human health. Thank you @carninci for the opportunity to present @humantechnopole on aging, genomics and AI approaches to identify longevity targets and drugs. https://t.co/ysDGHfJeY0
A combination of senolytics causes neuropathology in mice 👀 Dasatinib and quercetin trigger oligodendrocyte dysfunction and white matter injury in the CNS. Senolytics under more scrutiny? https://t.co/aDosJxeyxS

There are definitely worse places to discuss frailty, ageing, and using AI to discover drugs that preserve health. Kick off meeting of @EU_Commission UNION Marie Curie programme. https://t.co/BwvoPYj3KC

“If nobody builds it, everyone dies” Nick Bostrom’s latest piece on artificial superintelligence makes the point that, given we are all on course for dying in (by and large) the next few decades, developing a transformative technology like AGI is worth...